Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trial

for Gram-negative Bacteremia

11 locations incl. San Francisco

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06080698·Recruiting

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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

for Multiple Myeloma

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06121843·Phase 1·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

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A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

8 locations incl. San Carlos

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting

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SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia With FLT3/ITD Mutation

4 locations incl. Chapel Hill

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT06222580·Phase 1·Recruiting

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An Observational Study of Patients With Chronic Liver Disease

for Chronic Liver Disease

10 locations incl. Los Angeles

Sponsor: Target PharmaSolutions, Inc.

Sex: All·Age: 18+

Code: NCT05744713·Enrolling By Invitation

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

28 locations incl. Berkeley

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting

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Effect of Zinc on Glucose Homeostasis

for Prediabetic State

1 location in Lancaster

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 80

Code: NCT05835037·Phase 4·Recruiting

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A Global Prospective Observational Registry of Patients With Pompe Disease

for Pompe Disease

15 locations incl. Little Rock

Sponsor: Amicus Therapeutics

Sex: All·Age: All ages

Code: NCT06121011·Recruiting

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

21 locations incl. Orange

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting

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Study of Biodistribution, Metabolism, Excretion and Brain Uptake11C-M503

for Tauopathies

3 locations incl. New Haven

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT06303921·EARLY_Phase 1·Recruiting

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Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling

for Healthy

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05855525·Recruiting

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Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in West Reading

Sponsor: The Reading Hospital and Medical Center

Sex: All·Age: 18+

Code: NCT05893927·Recruiting

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Getting Out of the House: Using Behavioral Activation to Increase Community Participation

for Major Depressive Disorder

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06336616·Recruiting

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Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

for Differentiated Thyroid Cancer

5 locations incl. San Francisco

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 99

Code: NCT05783323·Phase 2·Recruiting

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An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents

for Overweight and Obesity

1 location in Philadelphia

Sponsor: Drexel University

Sex: Female·Age: 14 - 19·Accepts healthy volunteers

Code: NCT06147973·Recruiting

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Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting

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Tocilizumab in Lung Transplantation

for Lung Transplant

Drug: Tocilizumab

21 locations incl. Phoenix

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75

Code: NCT06033196·Phase 2·Recruiting

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A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

for Congenital Myasthenic Syndrome

6 locations incl. Sacramento

Sponsor: argenx

Sex: All·Age: 2+

Code: NCT06078553·Recruiting

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Multimodal Fetal and Placental Imaging and Biomarkers of Clinical Outcomes in Opioid Use Disorder

for Opioid Use Disorder

2 locations incl. Indianapolis

Sponsor: Indiana University

Sex: Female·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06415994·Enrolling By Invitation

Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

12 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

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Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

12 locations incl. Birmingham

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting

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A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

30 locations incl. Daphne

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06095505·Phase 2·Recruiting

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Preserving Geriatric Muscle With an Osteoporosis Medication

for Osteoporosis

1 location in Pittsburgh

Sponsor: Susan L. Greenspan

Sex: All·Age: 65+

Code: NCT06118905·Phase 4·Recruiting

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MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for Multiple Myeloma

Drug: Elranatamab

100 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06152575·Phase 3·Recruiting

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A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

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Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors

for Chronic Lymphocytic Leukemia

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 22+

Code: NCT06211413·Enrolling By Invitation

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

for Ductal Carcinoma in Situ

1 location in Pittsburgh

Sponsor: Finn, Olivera, PhD

Sex: Female·Age: 18+

Code: NCT06218303·Phase 1·Recruiting

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An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy

for Duchenne Muscular Dystrophy

25 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 4+

Code: NCT06270719·Enrolling By Invitation

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

for Metastatic Dedifferentiated Liposarcoma

Drug: Peposertib

16 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05711615·Phase 1·Recruiting

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Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

for Rhinoplasty

1 location in Hershey

Sponsor: Jessyka Lighthall

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05964868·Phase 3·Enrolling By Invitation

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: National Jewish Health

Sex: All·Age: 6+

Code: NCT06262282·Enrolling By Invitation

Nerve Transfer to Improve Function in High Level Tetraplegia

for Cervical Spinal Cord Injury

9 locations incl. Stanford

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06288763·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

491 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

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Project OASIS: Optimizing Approaches to Select Implementation Strategies

for Cirrhosis

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06061328·Enrolling By Invitation

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

for Esophageal Cancer

10 locations incl. Boston

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06123338·Phase 2·Recruiting

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A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

for Cystic Fibrosis

13 locations incl. Birmingham

Sponsor: ReCode Therapeutics

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06237335·Phase 2·Recruiting

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

6 locations incl. Los Angeles

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting

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Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

19 locations incl. La Mesa

Sponsor: Cumberland Pharmaceuticals

Sex: All·Age: 40+

Code: NCT05571059·Phase 2·Recruiting

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