Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,663 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,663 clinical trials

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Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF)

for Cystic Fibrosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05998629·Recruiting

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

117 locations incl. Goodyear

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

13 locations incl. San Francisco

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting

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Digital Assessment of Speech and Fine Motor Control in ALS

for Amyotrophic Lateral Sclerosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06315673·Recruiting

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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Point of Care Ultrasound for the Detection of Esophageal Food Bolus

for Esophageal Foreign Body

1 location in York

Sponsor: WellSpan Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06507670·Recruiting

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An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care (SUPPORT)

for Opioid Use Disorder

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06576323·Recruiting

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Group Coaching Study for Life Goals

for Students

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07083713·Enrolling By Invitation

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

for Trauma

15 locations incl. Tucson

Sponsor: Jason Sperry

Sex: All·Age: 18 - 90

Code: NCT05958342·Phase 2·Recruiting

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Global Paradise System US Post Approval Study

for Hypertension

39 locations incl. Sacramento

Sponsor: ReCor Medical, Inc.

Sex: All·Age: 18+

Code: NCT06297291·Recruiting

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A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

for Atrial Fibrillation

43 locations incl. Phoenix

Sponsor: Biosense Webster, Inc.

Sex: All·Age: 18 - 80

Code: NCT06455098·Recruiting

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Pain Control After Lumbar Spine Fusion

for Spine Fusion

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06484192·Phase 4·Enrolling By Invitation

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

for Systemic Lupus Erythematosus

10 locations incl. Los Angeles

Sponsor: NYU Langone Health

Sex: All·Age: 60+

Code: NCT05799378·Phase 3·Recruiting

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

101 locations incl. Phoenix

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting

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TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

for Cancer

31 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT06207032·Recruiting

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Implementing the NYU Electronic Patient Visit Assessment (ePVA) for Head and Neck Cancer In Rural and Urban Populations

for Head and Neck Cancer

5 locations incl. Kansas City

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT06030011·Recruiting

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

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Virtual Peer Coaching in Manual Wheelchair Skills

for Wheelchair

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06295146·Recruiting

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Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for Transthyretin Amyloidosis

30 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06465810·Recruiting

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A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

61 locations incl. Mobile

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06496178·Phase 3·Recruiting

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Community Resiliency Collective Efficacy Intervention

for Violence, Physical

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT05768217·Recruiting

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

33 locations incl. Tucson

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

372 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06203600·Phase 2, Phase 3·Recruiting

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Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for Triple-Negative Breast Cancer

88 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06393374·Phase 3·Recruiting

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Criterion-learning Naming Treatment For Addressing Comprehension Deficits in Aphasia

for Aphasia

1 location in Elkins Park

Sponsor: Albert Einstein Healthcare Network

Sex: All·Age: 18 - 89

Code: NCT07179458·Enrolling By Invitation

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

for Polymyositis, Dermatomyositis

43 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06455449·Phase 3·Recruiting

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Early Intervention to Promote Cardiovascular Health of Mothers and Children

for Cardiovascular Health

9 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06272045·Recruiting

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A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

for Glioblastoma

Drug: Niraparib

32 locations incl. Birmingham

Sponsor: Ivy Brain Tumor Center

Sex: All·Age: 18+

Code: NCT06388733·Phase 3·Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

for Large B-cell Lymphoma

60 locations incl. Gilbert

Sponsor: Allogene Therapeutics

Sex: All·Age: 18+

Code: NCT06500273·Phase 2·Recruiting

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Ex Onc SLED: a Study Utilizing a Weighted Sled for Horizontal Resistance Training

for Cancer

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 20 - 89

Code: NCT06610396·Recruiting

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A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

for Sickle Cell Disease

16 locations incl. Oakland

Sponsor: Editas Medicine, Inc.

Sex: All·Age: 12 - 50

Code: NCT06363760·Enrolling By Invitation

Liposomal Bupivacaine With Dexamethasone for Foot Surgery

for Foot Surgery

1 location in Philadelphia

Sponsor: Rothman Institute Orthopaedics

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06465992·Phase 4·Enrolling By Invitation

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

60 locations incl. Scottsdale

Sponsor: vTv Therapeutics

Sex: All·Age: 18+

Code: NCT06334133·Phase 3·Recruiting

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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

83 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting

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Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

for Chordoma of Spine

2 locations incl. Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06463262·Recruiting

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AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

for Mesial Temporal Lobe Epilepsy

18 locations incl. Birmingham

Sponsor: UniQure Biopharma B.V.

Sex: All·Age: 18 - 75

Code: NCT06063850·Phase 1, Phase 2·Recruiting

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A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for Ulcerative Colitis

Drug: Tofacitinib

40 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06095128·Phase 4·Recruiting

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APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

for Pre-Eclampsia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18 - 45

Code: NCT06408181·Phase 3·Recruiting

Apply to this trial