Paid Clinical Trials in Oklahoma

Oklahoma has 836 paid clinical trials enrolling now across cities including Oklahoma City, Tulsa and Edmond. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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836 clinical trials

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Antibiotic Prophylaxis to Prevent Obesity-Related Induction Complications in Nulliparae at Term 2.0

for Obesity in Pregnancy

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: Female·Age: 15 - 45

Code: NCT06488781·Phase 2·Recruiting

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

49 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting

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Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy

for Cancer Weight Loss

25 locations incl. Tucson

Sponsor: Endevica Bio

Sex: All·Age: 18+

Code: NCT06937177·Phase 2·Recruiting

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Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

40 locations incl. Ames

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06232044·Phase 1, Phase 2·Recruiting

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Dose-Dependent Effects of Low-Intensity Focused Ultrasound

for Healthy Controls

1 location in Tulsa

Sponsor: Laureate Institute for Brain Research, Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07099950·Recruiting

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A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

for Multiple Sclerosis

8 locations incl. Boston

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18 - 55

Code: NCT06735248·Phase 2·Recruiting

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Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

40 locations incl. Huntsville

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06966401·Phase 3·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

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A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

for Ovarian Cancer Recurrent

8 locations incl. New Haven

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06843447·Phase 1, Phase 2·Recruiting

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The Interaction of Body Composition, Sex Hormones and Exercise in Men

for Normal-weight Obesity

1 location in Stillwater

Sponsor: Oklahoma State University

Sex: Male·Age: 18 - 79·Accepts healthy volunteers

Code: NCT06970457·Recruiting

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Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies

for Cancer

8 locations incl. Fort Smith

Sponsor: Elephas

Sex: All·Age: 18+

Code: NCT07327489·Recruiting

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Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

for Hypertriglyceridemia

Drug: Plozasiran

76 locations incl. Bakersfield

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06822790·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

for Ovarian Cancer

30 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06824467·Phase 3·Recruiting

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Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

for Lung Non-Small Cell Carcinoma

243 locations incl. Jonesboro

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06498635·Phase 3·Recruiting

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Community Intervention to Improve CVD Risk Factor Control in Young American Indians

for Cholesterol, Elevated

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 39

Code: NCT06230705·Not Yet Recruiting

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

for Eosinophilic Asthma

34 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 12 - 75

Code: NCT06750289·Phase 3·Recruiting

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A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

for Type 2 Diabetes

Drug: Semaglutide

25 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06897475·Phase 2·Recruiting

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Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for Metastatic Head and Neck Squamous Cell Carcinoma

177 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06589804·Phase 3·Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

60 locations incl. Tucson

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

55 locations incl. Bakersfield

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

for Chronic Obstructive Pulmonary Disease (COPD)

68 locations incl. Cullman

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06878261·Phase 3·Recruiting

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

76 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting

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Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

for Bacterial Conjunctivitis

38 locations incl. Little Rock

Sponsor: Baxis Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT06911424·Phase 3·Recruiting

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

27 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for Chronic Obstructive Pulmonary Disease (COPD)

67 locations incl. Foley

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06883305·Phase 3·Recruiting

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An Open-Label Study of Azetukalner in Major Depressive Disorder

for Major Depressive Disorder

63 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06922110·Phase 3·Enrolling By Invitation

Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

31 locations incl. Tucson

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting

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Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

for Clear Cell Renal Cell Carcinoma

414 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06661720·Phase 3·Recruiting

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

194 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

658 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting

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Remote Physical Activity Programming to Improve Outcomes in Cancer Survivors With and Without Type 2 Diabetes

for Cancer Survivorship

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+

Code: NCT06725953·Recruiting

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52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

for Hypogonadism, Male

20 locations incl. Los Angeles

Sponsor: Halozyme Therapeutics

Sex: Male·Age: 12 - 17

Code: NCT06689085·Phase 3·Recruiting

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A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

for Psoriatic Arthritis

Drug: Tirzepatide

53 locations incl. Avondale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06864026·Phase 4·Recruiting

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Karma Ambispective Study

for Subjects Treated With Karma Fixation System as Part of Their Spine Surgery

4 locations incl. Gilbert

Sponsor: Spinal Elements

Sex: All·Age: 18+

Code: NCT07207187·Enrolling By Invitation

Efficacy of a Smartphone-Based JITAI to Reduce Drinking Among Adults Experiencing Homelessness

for Alcohol Misuse

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06821295·Phase 2, Phase 3·Recruiting

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

58 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting

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Efficacy and Safety Assessment of Experimental Bleaching Agents

for Tooth Discoloration

1 location in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06802614·Not Yet Recruiting

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

108 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06855498·Phase 3·Recruiting

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

190 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting

Apply to this trial