As of June 2026, 45 paid clinical trials are recruiting for Oncology in O'Fallon, Illinois. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
O'Fallon has approximately 121 recruiting research studies across a wide range of therapeutic areas. Illinois's research base includes Northwestern Medicine, Rush University Medical Center, University of Chicago Medicine, and Ann & Robert H. Lurie Children's Hospital, covering oncology, cardiology, and pediatric specialties.
Researchers run research studies in O'Fallon, IL at 20 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cancer Care Center of O'Fallon | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Malignant Solid Neoplasm | 87 |
| HSHS Saint Elizabeth's Hospital | Stage IV Lung Cancer AJCC v8, Breast Cancer, Prostate Adenocarcinoma | 50 |
| Cancer Care Specialists of Illinois | Breast Neoplasms, Cancer, Cancer of the Prostate | 4 |
| Cancer Care Specialists of Central Illinois | Breast Cancer, Multiple Myeloma, Squamous Cell Carcinoma of Head and Neck | 3 |
| Gateway Clinical Trials | Diabetic Foot Ulcer, Chronic Wound, Open Wound | 2 |
| HSHS St. Elizabeth's Hospital | Myasthenia Gravis | 2 |
| A53 | Myasthaenia Gravis | 1 |
| Cancer Care Specialist of Illinois | Breast Cancer, Early Stage Breast Cancer, HER2 + Breast Cancer | 1 |
| Cancer Care Specialists For Illinois | HR+/HER2- Breast Cancer | 1 |
| Cancer Care Specialists of Illinois - Cancer Care Center of O'Fallon | Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma | 1 |
| Clincial Research | Non-healing Wound, Venous Insufficiency of Leg, Venous Leg Ulcer | 1 |
| Clinical Res Ctr of S Illinois | Chronic Spontaneous Urticaria (CSU) | 1 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC) | 1 |
| HSHS Medical Group | New Onset Generalized Myasthenia Gravis (gMG) | 1 |
| HSHS St. Elizabeths Hospital | Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) | 1 |
| Hospital Sisters Health System (HSHS) - St Elizabeth's Hospital | Congenital Myasthenic Syndrome | 1 |
| Local Institution - 0324 | Breast Neoplasms | 1 |
| Prairie Cardiovascular | Heart Failure With Reduced Ejection Fraction, Hypertension, Pulmonary | 1 |
| Prairie Education and Research Cooperative and HSHS Medical Group | Myasthenia Gravis | 1 |
| Prairie Education and Research Cooperative-St. Elizabeth's | Concentric Hypertrophy, Heart Failure With Preserved Ejection Fraction | 1 |
Recruiting trials in O'Fallon grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Illinois are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Illinois studies must also comply with the Illinois Personal Information Protection Act (PIPA) and Biometric Information Privacy Act (BIPA) where applicable.
Hipa.ai aggregates every recruiting study in O'Fallon from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 121 recruiting clinical trials in O'Fallon, Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in O'Fallon compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in O'Fallon include Stage IV Lung Cancer AJCC v8 (8), Breast Cancer (6), Acute Myeloid Leukemia (5), Malignant Solid Neoplasm (5), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in O'Fallon on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in O'Fallon include Cancer Care Center of O'Fallon, HSHS Saint Elizabeth's Hospital, Cancer Care Specialists of Illinois, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in O'Fallon are Cancer & tumors (93), Mental health & behavior (2), Cardiovascular (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.