Clinical Trials at Icahn School of Medicine at Mount Sinai

As of June 2026, 269 paid clinical trials are recruiting at Icahn School of Medicine at Mount Sinai, located at 1 GUSTAVE L LEVY PLACE, NEW YORK, NY 10029, phone (212) 241-9065 in New York, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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269 clinical trials at Icahn School of Medicine at Mount Sinai

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MAGIC Ruxolitinib for aGVHD

for Acute Graft-versus-host Disease

Drug: Ruxolitinib

14 locations incl. Duarte

Sponsor: John Levine

Sex: All·Age: 18+

Code: NCT06936566·Phase 2·Recruiting

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Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

for Crohn Disease (CD)

3 locations incl. Beverly Hills

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 80

Code: NCT06976853·Phase 2·Recruiting

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Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen

for Prostate Cancer

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Male·Age: 18+

Code: NCT07141121·Recruiting

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A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy (IgAN)

28 locations incl. Little Rock

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT06935357·Phase 3·Recruiting

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SeizEAR Safety Study

for Epilepsy

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07088835·Recruiting

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Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

for Small Cell Lung Cancer Metastatic or Locally Advanced

20 locations incl. Huntsville

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07080242·Phase 1·Recruiting

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T1D Pregnancy & Me

for Diabetes Mellitus, Type 1

10 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+

Code: NCT06959316·Recruiting

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Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

for Long COVID-19

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06960928·Phase 3·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

51 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting

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A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis

35 locations incl. Chandler

Sponsor: Boston Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06920043·Phase 2·Recruiting

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Improving Medication Management in World Trade Center Responders

for Polypharmacy

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 50+

Code: NCT07022990·Recruiting

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

5 locations incl. Duarte

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

20 locations incl. Tucson

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting

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The Pivotal Study of RapidPulseTM Aspiration System

for Acute Ischemic Stroke

18 locations incl. Torrance

Sponsor: RapidPulse, Inc

Sex: All·Age: 18 - 80

Code: NCT06029491·Recruiting

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Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

for Ovarian Cancer

Drug: Bevacizumab

28 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT06819007·Phase 3·Recruiting

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

6 locations incl. Boston

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

55 locations incl. Birmingham

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting

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A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

9 locations incl. Orlando

Sponsor: NextCure, Inc.

Sex: All·Age: 18+

Code: NCT06792552·Phase 1·Recruiting

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A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

Drug: Monalizumab

4 locations incl. Tampa

Sponsor: John Sfakianos

Sex: All·Age: 18+

Code: NCT06503614·Phase 2·Recruiting

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Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)

for Small Cell Lung Cancer

1 location in New York

Sponsor: Oncology Center of Biochemical Education And Research

Sex: All·Age: 18 - 85

Code: NCT06717243·Recruiting

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A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

19 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

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Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

for Major Depressive Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 90

Code: NCT06559826·Phase 2·Recruiting

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Treatment of Focal Ventricular Tachycardias Using a Pulsed Field Ablation From a Point Ablation Catheter Short Title FOCUS-PFA

for Focal Ventricular Arrhythmias

1 location in New York

Sponsor: Vivek Reddy

Sex: All·Age: 18+

Code: NCT06747013·Enrolling By Invitation

Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

20 locations incl. Birmingham

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06560021·Enrolling By Invitation

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

for IgA Nephropathy

37 locations incl. Birmingham

Sponsor: Calliditas Therapeutics AB

Sex: All·Age: 18+

Code: NCT06712407·Phase 4·Recruiting

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Cocaine Cue-reactivity Incubation Study

for Cocaine Use Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 65

Code: NCT07091877·Recruiting

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Building Community Resilience Program

for Resilience, Psychological

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06771167·Recruiting

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A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

for B-cell Malignancy

18 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06634589·Phase 1, Phase 2·Recruiting

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Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

54 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

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Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

for Lymphoma

Drug: Epcoritamab

3 locations incl. Stanford

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06510361·Phase 2·Recruiting

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Cognitive Reappraisal Training for Borderline Personality (BPD)

for Borderline Personality Disorder

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 55

Code: NCT06772831·Recruiting

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LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

for Metabolic Dysfunction Associated Steatohepatitis

Drug: Survodutide

125 locations incl. Peoria

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06632457·Phase 3·Recruiting

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Behavioral Therapy for Crohn's Disease

for Crohn's Disease

2 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18 - 65

Code: NCT06512597·Recruiting

Apply to this trial

tVNS in Long COVID-19

for Long COVID

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 21 - 70

Code: NCT06585254·Recruiting

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Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing

for Diabetic Foot Ulcers (DFUs)

3 locations incl. Coconut Creek

Sponsor: Reprise Biomedical, Inc.

Sex: All·Age: 18+

Code: NCT06939686·Recruiting

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A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)

for Primary Myelofibrosis

13 locations incl. Palo Alto

Sponsor: Ajax Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06343805·Phase 1·Recruiting

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A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

35 locations incl. California City

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting

Apply to this trial