Brain disorders Clinical Trials in New York, NY

As of June 2026, 135 paid clinical trials are recruiting for Brain disorders in New York, New York. Brain disorder trials span neurodegenerative diseases, stroke, traumatic brain injury, and neuromuscular conditions — testing both pharmacologic and rehabilitative approaches to slow progression and improve function. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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135 clinical trials for Brain disorders

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Mobile Cognitive Behavioral Therapy for Stroke

for Anxiety

1 location in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 40 - 79

Code: NCT06689878·Recruiting

Apply to this trial

Resilient Together for Dementia (RT-D)

for Dementia

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06619327·Recruiting

Apply to this trial

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

for Alzheimer Disease

40 locations incl. Phoenix

Sponsor: Lighthouse Pharmaceuticals, Inc.

Sex: All·Age: 55 - 80

Code: NCT06847321·Phase 2·Recruiting

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

41 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting

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Evaluation of the Abbott i-STAT TBI Biomarker Test

for Traumatic Brain Injury

3 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT06766435·Recruiting

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

for Aphasia

1 location in New York

Sponsor: City University of New York

Sex: All·Age: 21 - 80·Accepts healthy volunteers

Code: NCT04142866·Recruiting

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Genetic and Environmental Risk Factors for Hemorrhagic Stroke

for Stroke

7 locations incl. Chicago

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00682695·Recruiting

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A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

for Parkinson's Disease

2 locations incl. Lexington

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 40 - 72

Code: NCT06753331·Phase 1, Phase 2·Recruiting

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Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

for Mild Cognitive Impairment (MCI)

4 locations incl. Miami

Sponsor: Columbia University

Sex: All·Age: 55 - 89

Code: NCT06601933·Phase 2·Recruiting

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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05552157·Phase 2, Phase 3·Recruiting

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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06647498·Phase 2, Phase 3·Recruiting

Apply to this trial

Cognition and Imaging With Tigertriever

for Stroke

3 locations incl. Los Angeles

Sponsor: Rapid Medical

Sex: All·Age: 18 - 75

Code: NCT05531461·Recruiting

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Personalized Antisense Oligonucleotide for Participants With CHCHD10 ALS

for Amyotrophic Lateral Sclerosis

1 location in New York

Sponsor: n-Lorem Foundation

Sex: All·Age: 18+

Code: NCT07095686·Phase 1, Phase 2·Enrolling By Invitation

SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes

for Stroke

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 75

Code: NCT06397937·Recruiting

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Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease

for Parkinson Disease

1 location in New York

Sponsor: Teachers College, Columbia University

Sex: All·Age: 50 - 80

Code: NCT06540989·EARLY_Phase 1·Recruiting

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Early Age-Related Hearing Loss Investigation (EARHLI)

for Alzheimer Disease

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 55 - 75

Code: NCT06174038·Recruiting

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

Apply to this trial

PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

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Prediction of Anxiety and Memory State

for Anxiety

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 18 - 55

Code: NCT06551090·Recruiting

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A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

87 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting

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A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

20 locations incl. Los Angeles

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting

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Task Specific Training for Advanced Multiple Sclerosis

for Multiple Sclerosis

1 location in New York

Sponsor: Hunter College of City University of New York

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06506929·Recruiting

Apply to this trial

Eccentric Exercise and Fatigue in Multiple Sclerosis

for Multiple Sclerosis

1 location in New York

Sponsor: Hunter College of City University of New York

Sex: All·Age: 18 - 75

Code: NCT06505421·Recruiting

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Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

for Mild Cognitive Impairment

1 location in New York

Sponsor: Columbia University

Sex: All·Age: 55+

Code: NCT05655325·Recruiting

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Study of ALTO-101 in Patients With Schizophrenia

for Schizophrenia

14 locations incl. Garden Grove

Sponsor: Alto Neuroscience

Sex: All·Age: 21 - 55

Code: NCT06502964·Phase 2·Recruiting

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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

13 locations incl. Irvine

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting

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The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

for Obstructive Sleep Apnea

4 locations incl. Tucson

Sponsor: California Pacific Medical Center Research Institute

Sex: All·Age: 55 - 85

Code: NCT05988385·Recruiting

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MENTOR Wellness Program

for Traumatic Brain Injury

1 location in New York

Sponsor: NYU Langone Health

Sex: All·Age: 18 - 70

Code: NCT06148324·Recruiting

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A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

for Multiple Sclerosis

17 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18 - 60

Code: NCT06220201·Phase 1·Recruiting

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

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Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care

for Epilepsy

2 locations incl. New York

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06346262·Phase 4·Recruiting

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Evaluating the Efficacy of the Pain Identification and Communication Toolkit

for Caregiver Burden

1 location in New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 21+

Code: NCT06168604·Recruiting

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

51 locations incl. Birmingham

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting

Apply to this trial

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

25 locations incl. Phoenix

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting

Apply to this trial

Effect of Cooling on Balance Performance in Multiple Sclerosis

for Multiple Sclerosis

1 location in New York

Sponsor: Hunter College of City University of New York

Sex: All·Age: 18 - 75

Code: NCT06094855·Recruiting

Apply to this trial

CTSN Embolic Protection Trial

for Delirium

24 locations incl. North Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting

Apply to this trial

Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients

for Mild Cognitive Impairment

2 locations incl. Menands

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 55+

Code: NCT05016219·Recruiting

Apply to this trial

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

for Epilepsy

4 locations incl. Miami

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04419272·Phase 4·Recruiting

Apply to this trial

Community-based Implementation of Online EmReg

for Traumatic Brain Injury

1 location in New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05933629·Recruiting

Apply to this trial

Conditions in Brain disorders (New York, NY)

Stroke· 31 Parkinson's disease· 20 Alzheimer's disease· 18 Mild cognitive impairment (MCI)· 17 Multiple sclerosis· 16 Dementia· 11 Epilepsy· 11 ALS (amyotrophic lateral sclerosis)· 10 Traumatic brain injury (TBI)· 8 Cognitive impairment / decline· 5 Myasthenia gravis· 4 Aphasia· 2 Huntington disease· 1