Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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855303-RNA Biomarker Validation

for Fractures, Bone

7 locations incl. Sacramento

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06872775·Enrolling By Invitation

An International Observational Study of Adults With Acute Infection

for Infectious Disease

18 locations incl. Tucson

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting

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Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT

for Refractory Ventricular Tachycardia

5 locations incl. Birmingham

Sponsor: Thermedical, Inc.

Sex: All·Age: 18+

Code: NCT05337241·Recruiting

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Comparison of Body Composition Changes With Weight Loss Interventions

for Obesity

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 21 - 65

Code: NCT07115069·Recruiting

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VoiceLove: An App-Based COMMunication Tool Designed to Address DeliriUm and Improve Family ENgagement and PatIent/Family SatisfaCtion in CriticAlly Ill PaTiEnts (COMMUNICATE)

for Critical Illness

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06923462·Recruiting

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

32 locations incl. Scottsdale

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting

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Endoscopic Gastroenterostomy Versus Surgical Gastrojejunostomy

for Malignant Gastric Outlet Obstruction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06567691·Enrolling By Invitation

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

for Renal Cell Carcinoma

7 locations incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 120

Code: NCT07049926·Phase 1, Phase 2·Recruiting

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A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

for High-risk Myelodysplastic Syndrome

11 locations incl. Duarte

Sponsor: Crossbow Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06994676·Phase 1·Recruiting

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

31 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting

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XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

for Heart Transplant

14 locations incl. La Jolla

Sponsor: XVIVO Perfusion

Sex: All·Age: 18+

Code: NCT06895070·Recruiting

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PRECIDENTD Engagement Methods for Sites

for Stakeholder Engagement

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07053046·Enrolling By Invitation

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

for Type 1 Diabetes Mellitus

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06609356·EARLY_Phase 1·Recruiting

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Study With Phage for CF Subjects With Pseudomonas Lung Infection

for Chronic Pseudomonas Aeruginosa Infection

14 locations incl. Birmingham

Sponsor: BiomX Ltd

Sex: All·Age: 18+

Code: NCT06998043·Phase 2·Recruiting

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Effect of Rose Odor Exposure on Ictal Apnea

for Epilepsy

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07116421·EARLY_Phase 1·Recruiting

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Comparison of Two Over the Counter Intravaginal Devices for the Treatment of Stress Urinary Incontinence

for Stress Urinary Incontinence in Women

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 21+

Code: NCT06698627·Enrolling By Invitation

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

12 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting

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A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

for Heart Failure

29 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 40 - 84

Code: NCT06979362·Phase 2·Recruiting

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

66 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting

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Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Drug: Empagliflozin

3 locations incl. Baltimore

Sponsor: Gustavo A Heresi, MD, MS

Sex: All·Age: 18+

Code: NCT06992440·Phase 2·Enrolling By Invitation

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for Parkinsons Disease (PD)

31 locations incl. Sun City

Sponsor: BlueRock Therapeutics

Sex: All·Age: 45 - 75

Code: NCT06944522·Phase 3·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting

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Project PAIR: Parent-implemented Articulation Intervention With Recast

for Hearing Impaired Children

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 4 - 10

Code: NCT06936696·Recruiting

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Attentional Mechanisms in SCD

for Subjective Cognitive Decline

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06002477·EARLY_Phase 1·Recruiting

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Neural Basis of Human Working Memory

for Memory Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07617506·Recruiting

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Real-World Data Collection of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis When Used in Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) to Treat Aortoiliac Occlusive Disease

for Aortoiliac Occlusive Disease

19 locations incl. Fresno

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 100

Code: NCT06872905·Recruiting

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Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

21 locations incl. Little Rock

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

15 locations incl. Huntsville

Sponsor: Biogen

Sex: All·Age: 18 - 80

Code: NCT06962800·Phase 3·Recruiting

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A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)

for Stress Urinary Incontinence (SUI)

13 locations incl. Los Angeles

Sponsor: UroMems SAS

Sex: Male·Age: 22+

Code: NCT06968741·Recruiting

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

50 locations incl. Glendale

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819891·Phase 3·Recruiting

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

18 locations incl. Phoenix

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

23 locations incl. Duarte

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting

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Tube Size Randomized Trial During Emergency Tracheal Intubation

for Acute Respiratory Failure

7 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06939361·Enrolling By Invitation

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

6 locations incl. Scottsdale

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting

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Tirzepatide in PWS, HO and GNSO

for Prader-Willi Syndrome

Drug: Tirzepatide

3 locations incl. Saint Paul

Sponsor: Grace Kim

Sex: All·Age: 18 - 26

Code: NCT06901245·Phase 4·Recruiting

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Atomoxetine in Melanocortin Obesity Syndrome

for Melanocortin Obesity Syndrome

2 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 6+

Code: NCT06899178·Phase 2·Not Yet Recruiting

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

for Hematuria - Cause Not Known

15 locations incl. Homewood

Sponsor: Pacific Edge Limited

Sex: All·Age: 18 - 88

Code: NCT06394869·Recruiting

Apply to this trial