Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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A Study Of Senyo Health With Comorbid Alcohol Use Disorder Treatment In Bipolar Patients

for Bipolar Disorder

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07556861·Not Yet Recruiting

PrP-targeting siRNA Safety & Mechanism Study

for Prion Disease

5 locations incl. Boston

Sponsor: Broad Institute of MIT and Harvard

Sex: All·Age: 18+

Code: NCT07444580·Phase 1·Recruiting

Apply to this trial

Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

9 locations incl. Encino

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Not Yet Recruiting

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for Locally Advanced Pancreatic Adenocarcinoma

274 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06998940·Phase 3·Recruiting

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

12 locations incl. Los Angeles

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting

Apply to this trial

Glucose and Activity Tracking for Sedentary Behavior Interventions in Older People With Type 2 Diabetes (TRACK T2D)

for Diabetes Mellitus, Type 2

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 55+

Code: NCT07524205·Recruiting

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

14 locations incl. Sacramento

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting

Apply to this trial

A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

15 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

Apply to this trial

Adapt NK for High Risk Myeloid Diseases as Bridge to Allo HSCT

for Relapsed Adult AML

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT07591649·Phase 1, Phase 2·Recruiting

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A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for Solid Tumors

Drug: Adagrasib

17 locations incl. Phoenix

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07415031·Phase 2·Recruiting

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Project REACH: A Comprehensive Telehealth Intervention at Syringe Service Programs to Engage People Who Use Drugs

for Substance Use

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07433712·Recruiting

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MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

for Sepsis

3 locations incl. Rochester

Sponsor: Health Discovery Labs

Sex: All·Age: 18 - 85

Code: NCT07362862·Recruiting

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

10 locations incl. Birmingham

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting

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Establishing the Preliminary Utility of a Novel Pediatric Manual Mobile Standing Wheelchair

for Spina Bifida

1 location in Saint Paul

Sponsor: Optimal Mobility, Inc

Sex: All·Age: 8 - 17

Code: NCT07290556·Not Yet Recruiting

Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

16 locations incl. Orange

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting

Apply to this trial

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

Horizon Two: HR NDMM (MMRC-100)

for High Risk Newly Diagnosed Multiple Myeloma

7 locations incl. Atlanta

Sponsor: Multiple Myeloma Research Consortium

Sex: All·Age: 18+

Code: NCT07053436·Phase 2·Recruiting

Apply to this trial

Radiation Therapy (RT) for Parkinson's Disease (PD)

for Parkinson's Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 45 - 70

Code: NCT07218952·Enrolling By Invitation

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

23 locations incl. Duarte

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting

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MCG In Long QT Syndrome

for Atrial Fibrillation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07270211·Not Yet Recruiting

A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

for Hearing Loss, Bilateral Sensorineural

11 locations incl. Englewood

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT07287124·Recruiting

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Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

for Malignant Digestive System Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07456852·Phase 1, Phase 2·Recruiting

Apply to this trial

FET PET/CT Imaging To Localize Pituitary Adenomas In Cushing Disease

for Cushing Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07460232·EARLY_Phase 1·Recruiting

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Mindfulness-Based Stress Reduction for Emotional Recovery After Stroke

for Chronic Stroke Patients

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 18+

Code: NCT07491861·Recruiting

Apply to this trial

ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

for Dravet Syndrome

3 locations incl. Ann Arbor

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 2 - 12

Code: NCT07531745·Phase 1, Phase 2·Recruiting

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A Study Of Synthetic THC And Sleep

for Obstructive Sleep Apnea

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 70

Code: NCT07570953·Phase 2, Phase 3·Not Yet Recruiting

Axelopran for Advanced Cancer in Patients Receiving Opioids

for Breast Cancer

2 locations incl. Saint Louis Park

Sponsor: HealthPartners Institute

Sex: All·Age: 18+

Code: NCT07354919·Phase 2·Recruiting

Apply to this trial

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

for Anaplastic Oligodendroglioma

Drug: Retifanlimab

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07468136·Phase 1, Phase 2·Not Yet Recruiting

First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma

for Astrocytoma

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT07560865·Phase 1·Recruiting

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VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma

for Advanced Clear Cell Renal Cell Carcinoma

Drug: Ipilimumab

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07510334·Phase 2·Recruiting

Apply to this trial

The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study

for Relapsing Remitting Multiple Sclerosis

6 locations incl. Atlanta

Sponsor: SetPoint Medical Corporation

Sex: All·Age: 22 - 50

Code: NCT06796504·Recruiting

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A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

for Lymphoma, Non-Hodgkin's

Drug: LY4584180

21 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07226843·Phase 1·Recruiting

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A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

for Retinitis Pigmentosa

2 locations incl. Boston

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT06891885·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

for Smoking Cessation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07487818·Phase 2, Phase 3·Not Yet Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

for Macular Degeneration

9 locations incl. Mountain View

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 50+

Code: NCT07496567·Phase 2, Phase 3·Recruiting

Apply to this trial

Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass

for Weight Regain

9 locations incl. Irvine

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07015424·Recruiting

Apply to this trial

A Study Of Milk Consumption In Metabolic Syndrome

for Metabolic Syndrome

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 70

Code: NCT07401888·Recruiting

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

15 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting

Apply to this trial

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

for Urinary Retention Postoperative

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 35+

Code: NCT07174349·Phase 4·Recruiting

Apply to this trial