Clinical Trials at University of Minnesota

As of June 2026, 327 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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327 clinical trials at University of Minnesota

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Multi-level Predictors of Structural Racism and Discrimination and Associations With Health and Well-being Across the Life Course in Diverse Families

for Racially/Ethnically Diverse Families From Urban Settings

2 locations incl. Athens

Sponsor: University of Colorado, Denver

Sex: All·Age: 8 - 18

Code: NCT05744973·Recruiting

Apply to this trial

Maternal Probiotic Supplementation for Improved Outcomes in Infants of Diabetic Mothers

for Infant of Diabetic Mother

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 21 - 45

Code: NCT05467150·Recruiting

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

Diabetes in African Youth

for type1diabetes

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 4 - 26

Code: NCT05454176·Phase 4·Recruiting

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North American Prodromal Synucleinopathy Consortium Stage 2

for REM Sleep Behavior Disorder

8 locations incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05826457·Enrolling By Invitation

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

for Acute Coronary Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05426083·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

for B-Cell Non-Hodgkin Lymphoma

25 locations incl. Clovis

Sponsor: ADC Therapeutics S.A.

Sex: All·Age: 18+

Code: NCT04970901·Phase 1·Recruiting

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

32 locations incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting

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BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

for Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

6 locations incl. Duarte

Sponsor: PeproMene Bio, Inc.

Sex: All·Age: 18+

Code: NCT05370430·Phase 1·Recruiting

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Intracranial Stimulation Mapping In Epilepsy

for Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05290610·Recruiting

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A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

for FSGS

54 locations incl. Birmingham

Sponsor: Dimerix Bioscience Pty Ltd

Sex: All·Age: 12 - 80

Code: NCT05183646·Phase 3·Recruiting

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Transdiagnostic Cognitive Biomarkers

for Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04864080·Recruiting

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Community-based Exercise Following Revascularization for PAD

for Peripheral Artery Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 40 - 90

Code: NCT04252950·Recruiting

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Trigeminal Neuralgia Electrophysiology

for Trigeminal Neuralgia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05269472·Recruiting

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Neurobiological and Psychological Maintenance Mechanisms Associated With Anticipatory Reward in Bulimia Nervosa

for Bulimia Nervosa

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT04917068·Recruiting

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Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

for Alcohol Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT05062369·Recruiting

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Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05068908·Recruiting

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The Cardiovascular Impact of Hot Flushes

for Hot Flashes

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 40 - 70·Accepts healthy volunteers

Code: NCT05251324·Recruiting

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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

25 locations incl. Birmingham

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting

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Visual Remapping to Aid Reading With Field Loss

for Age-related Macular Degeneration

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT03848663·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT05197920·Recruiting

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The COCOA-PAD II Trial

for Peripheral Artery Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 55+

Code: NCT04794530·Phase 3·Recruiting

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First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

9 locations incl. Fullerton

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting

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A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer

for Endometrial Cancer

21 locations incl. Duarte

Sponsor: Alliance Foundation Trials, LLC.

Sex: Female·Age: 18+

Code: NCT04486352·Phase 1, Phase 2·Recruiting

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PCS in Severe Treatment Resistant Depression

for Treatment Resistant Depression

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22 - 70

Code: NCT04124341·Recruiting

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

9 locations incl. San Francisco

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Improving Spinal Cord Stimulation With ECAPS

for Chronic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT04938245·Recruiting

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Stimulation of the Larynx to Treat Unexplained Chronic Cough

for Cough

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 88

Code: NCT05273190·Recruiting

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Poke and a Placebo

for Anesthesia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT04497220·Recruiting

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Vertical Sleeve Gastrectomy and Lifestyle Modification for the Treatment of Non-Alcoholic Steatohepatitis

for NASH - Nonalcoholic Steatohepatitis

4 locations incl. San Francisco

Sponsor: University of Minnesota

Sex: All·Age: 30 - 70

Code: NCT03587831·Recruiting

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

57 locations incl. Long Beach

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting

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Multiple Objective Particle Swarm Optimization Postural Instability Gait Disorder

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 89

Code: NCT05893186·EARLY_Phase 1·Recruiting

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

46 locations incl. Gilbert

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

49 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting

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Evaluation of a Mixed Meal Test for Diagnosis and Characterization and Type 3c Diabetes Mellitus Secondary to Pancreatic Cancer and Chronic Pancreatitis (DETECT)

for Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 30 - 84

Code: NCT03460769·Recruiting

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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

for Pulmonary Arterial Hypertension

12 locations incl. La Jolla

Sponsor: Aria CV, Inc

Sex: All·Age: 18+

Code: NCT04555161·Recruiting

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Neuroplasticity in Parkinson's Disease

for Parkinson

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT05286736·Recruiting

Apply to this trial