Clinical Trials at University of Minnesota

As of June 2026, 327 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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327 clinical trials at University of Minnesota

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PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

47 locations incl. Phoenix

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting

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A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

for Hematologic Malignancy

17 locations incl. Duarte

Sponsor: CRISPR Therapeutics AG

Sex: All·Age: 18+

Code: NCT06208878·Enrolling By Invitation

Trigeminal Evoked Responses to Improve Rhizotomy

for Trigeminal Neuralgia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05738096·EARLY_Phase 1·Recruiting

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A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

for Prostatic Neoplasms

11 locations incl. Aurora

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT06095089·Phase 1·Recruiting

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IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

for NHL

12 locations incl. Los Angeles

Sponsor: Indapta Therapeutics, INC.

Sex: All·Age: 18+

Code: NCT06119685·Phase 1, Phase 2·Recruiting

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An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant

for Chronic Kidney Disease (CKD)

9 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT05106387·Recruiting

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Feasibility of Transcranial Focused Ultrasound to Measure Brain Tumor

for Cranial Neurosurgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05755399·Recruiting

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

22 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting

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The Teaspoon Study - Telefitting Spinal Cord Stimulation for Pain

for Spinal Cord Injuries

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT05741788·Recruiting

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Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

for Hidradenitis Suppurativa

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06058520·EARLY_Phase 1·Recruiting

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Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

for Obesity

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75

Code: NCT06226077·Phase 1, Phase 2·Recruiting

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Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

for Hearing

2 locations incl. Minneapolis

Sponsor: Marquette University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06465979·Recruiting

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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

for Refractory Epilepsy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05493722·EARLY_Phase 1·Recruiting

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Coordinated Reset Deep Brain Stimulation for Essential Tremor

for Essential Tremor

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05897775·Phase 1·Recruiting

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SMART Exercise for PAD

for Peripheral Arterial Disease

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT06032065·Phase 3·Recruiting

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Listening Effort in Cochlear Implant Users

for Auditory Perception

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06516575·Recruiting

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

37 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting

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Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

for Sepsis

10 locations incl. Gainesville

Sponsor: University of Minnesota

Sex: All·Age: 65+

Code: NCT05758246·Phase 2·Recruiting

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Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease

for Gaucher Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05843552·Recruiting

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

44 locations incl. Phoenix

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Sleep-specific DBS Therapy in Parkinson's Disease

for Deep Brain Stimulation

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05962489·Recruiting

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ASSESSING THE GAY MALE EXPERIENCE WITH ANAL CANCER PREVENTION STRATEGIES

for Anal Cancer

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT05628194·Recruiting

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Evaluation of the SCALED (SCaling AcceptabLE cDs)

for Traumatic Brain Injury

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05628207·Recruiting

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The Ailliance Post-Market Clinical Study

for Spinal Deformity

22 locations incl. Tucson

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting

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Neuroplasticity in RBD

for REM Sleep Behavior Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT05471960·Recruiting

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Molecular Epidemiology of Pediatric Germ Cell Tumors

for Germ Cell Tumor

1 location in Minneapolis

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT05564026·Recruiting

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ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I

for Mucopolysaccharidosis IH/S

2 locations incl. Oakland

Sponsor: Immusoft of CA, Inc.

Sex: All·Age: 10+

Code: NCT05682144·Phase 1·Recruiting

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Circuit-Based Deep Brain Stimulation for Parkinson's Disease P1A2&3 Catalyst

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 21+

Code: NCT05658302·Recruiting

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A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

for Neonatal Seizure

2 locations incl. San Diego

Sponsor: University of California, San Diego

Sex: All·Age: Up to 1 Month

Code: NCT05610085·Phase 2·Recruiting

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Cognitive and Affective Processes Online

for Depression

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05736471·Recruiting

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Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy

for Intracranial Pressure Increase

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 4+·Accepts healthy volunteers

Code: NCT04046523·Recruiting

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BEETroot Juice to Reverse Functional Impairment in PAD

for Peripheral Artery Disease

4 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 50+

Code: NCT05624125·Recruiting

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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

for Gaucher Disease, Type 3

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 80

Code: NCT05586243·Recruiting

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Udall Project 2 Aim 2A&C

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: All ages

Code: NCT05656586·Recruiting

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Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

for Bladder Carcinoma in Situ (CIS)

6 locations incl. Gilbert

Sponsor: Fidia Farmaceutici s.p.a.

Sex: All·Age: 18+

Code: NCT05024773·Phase 3·Recruiting

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

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Maternal Stress, Milk Composition, and Preterm Neurodevelopment

for Prematurity

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 28 Weeks - 34 Weeks

Code: NCT05537454·Recruiting

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CIFASD 5 tDCS and Cognitive Training

for Fetal Alcohol Spectrum Disorders

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 8 - 17

Code: NCT05456321·Recruiting

Apply to this trial