The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
for Metastatic Breast Cancer
73 locations incl. Chandler
Sponsor: American Society of Clinical Oncology
Sex: All·Age: 65+
Code: NCT06377852·Phase 3·Recruiting
Breast oncology Clinical Trials in Methuen, MA
As of June 2026, 4 paid clinical trials are recruiting for Breast oncology in Methuen, Massachusetts. Breast oncology research tests new hormone therapies, HER2-targeted agents, PARP inhibitors, antibody-drug conjugates, and immunotherapy combinations across early-stage and metastatic disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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4 clinical trials for Breast oncology
·Clear filters·↓ Download CSVA Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
for Breast Cancer
165 locations incl. Daphne
Sponsor: Stemline Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06492616·Phase 3·Recruiting
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
for Triple Negative Breast Cancer
184 locations incl. Birmingham
Sponsor: Gilead Sciences
Sex: All·Age: 18+
Code: NCT05633654·Phase 3·Recruiting
ATEMPT 2.0: Adjuvant T-DM1 vs TH
for Breast Cancer
53 locations incl. San Francisco
Sponsor: Dana-Farber Cancer Institute
Sex: All·Age: 18+
Code: NCT04893109·Phase 2·Recruiting
About research studies in Methuen
Methuen has approximately 23 recruiting research studies across a wide range of therapeutic areas. Massachusetts is a global epicenter of biomedical research, anchored by Harvard-affiliated hospitals (MGH, Brigham and Women's, Dana-Farber), Boston Children's Hospital, and the Kendall Square biotech corridor in Cambridge.
Top Research Study Locations in Methuen
Researchers run research studies in Methuen, MA at 12 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Dana Farber-Merrimack Valley | Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma | 7 |
| ActivMed Practices and Research | Alzheimer's Disease, Chronic Low-back Pain, Diabetic Neuropathic Pain | 2 |
| Activmed Practices & Research, Llc - Methuen | Depression, Major Depressive Disorder, Major Depressive Disorder (MDD) | 2 |
| Dana-Farber Cancer Instiute - Merrimack Valley | Breast Cancer, Gastrointestinal Cancer, HER2-positive Breast Cancer | 2 |
| ActivMed Practices & Research | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension | 1 |
| ActivMed Practices & Research, Inc. | Cognitive Function, Contrast Media, Motor Function | 1 |
| Dana Farber Cancer Institute - Merrimack Valley | Breast Cancer | 1 |
| Dana Farber Cancer Institute at Merrimack Valley | B-cell Malignancy, Low-grade, Hematological Malignancies, IgG Monoclonal Gammopathy of Uncertain Significance | 1 |
| Dana-Farber Cancer Institude at Merrimack Valley | Triple Negative Breast Cancer | 1 |
| Dana-Farber Cancer Institute - Merrimack Valley | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
| Dana-Farber Cancer Institute Merrimack Valley | Metastatic Breast Cancer | 1 |
| Dana-Farber Cancer Instiute Merrimack Valley | EGFR Gene Mutation, Lung Cancer | 1 |
Active & Upcoming Studies in Methuen (2026)
Recruiting trials in Methuen grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (15 active studies)
- EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations · Dana-Farber Cancer Institute
- Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer · Phase 3 · Alliance for Clinical Trials in Oncology
Mental health & behavior (1 active study)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
Diabetes & metabolic (1 active study)
Neurology & pain (1 active study)
- A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain · Phase 2 · Eli Lilly and Company
Cardiovascular (1 active study)
Common conditions studied in Methuen
- Breast Cancer (2 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Major Depressive Disorder (2 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.
- Stage IIIB Lung Cancer AJCC v8 (2 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Advanced Esophageal Adenocarcinoma (1 active study). Recruiting Advanced Esophageal Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Gastric Adenocarcinoma (1 active study). Recruiting Advanced Gastric Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Gastroesophageal Junction Adenocarcinoma (1 active study). Recruiting Advanced Gastroesophageal Junction Adenocarcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Methuen
- Alliance for Clinical Trials in Oncology
- Dana-Farber Cancer Institute
- National Cancer Institute (NCI)
- American Society of Clinical Oncology
- Axsome Therapeutics, Inc.
Local regulations and guidelines
Clinical trials in Massachusetts are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Massachusetts trials follow additional state privacy requirements enforced under 201 CMR 17.00 and oversight from the Massachusetts Department of Public Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Methuen. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Methuen
Hipa.ai aggregates every recruiting study in Methuen from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Methuen?
There are approximately 23 recruiting clinical trials in Methuen, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Methuen pay participants?
Most recruiting trials in Methuen compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Methuen?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Methuen?
The most common conditions under active study in Methuen include Breast Cancer (2), Major Depressive Disorder (2), Stage IIIB Lung Cancer AJCC v8 (2), Advanced Esophageal Adenocarcinoma (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Methuen?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Methuen on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Methuen?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Methuen?
Recruiting research sites in Methuen include Dana Farber-Merrimack Valley, ActivMed Practices and Research, Activmed Practices & Research, Llc - Methuen, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Methuen right now?
The largest active categories in Methuen are Cancer & tumors (15), Mental health & behavior (1), Diabetes & metabolic (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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