Paid Clinical Trials in Maryland

Maryland has 2,900 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,899 clinical trials

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Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

for Locally Advanced Malignant Solid Neoplasm

Drug: Durvalumab

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03907475·Phase 2·Recruiting

Apply to this trial

Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

for Overactive Bladder

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04020510·Phase 4·Recruiting

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Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

for Clinical Stage I Esophageal Adenocarcinoma AJCC v8

95 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03801876·Phase 3·Recruiting

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Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 85

Code: NCT03986034·Phase 2·Recruiting

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Nicotinic Receptor Genetic Variation and Alcohol Reward

for Alcohol Drinking

1 location in Bethesda

Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT03294460·Phase 1·Recruiting

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Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder

for Opioid-Related Disorders

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 21 - 60·Accepts healthy volunteers

Code: NCT03745339·Recruiting

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Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations

for Renal Cell Carcinoma

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 120

Code: NCT03786796·Phase 2·Recruiting

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Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy

for Neovascular Age-related Macular Degeneration

9 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT03999801·Phase 2·Enrolling By Invitation

Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma

for Salivary Gland Carcinoma

7 locations incl. Chicago

Sponsor: Manish Patel

Sex: All·Age: 18+

Code: NCT03942653·Phase 2·Recruiting

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

49 locations incl. Duarte

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting

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Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

579 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting

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Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery

for Pituitary Neoplasm

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 85

Code: NCT03678389·Recruiting

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Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

275 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03739814·Phase 2·Recruiting

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Collection of Bone Marrow Aspirate From Normal Volunteers

for Normal Aging

1 location in Baltimore

Sponsor: National Institute on Aging (NIA)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT03949647·Recruiting

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A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

for Amputation

4 locations incl. Bethesda

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03882073·Recruiting

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The Johns Hopkins Heartburn Center Registry

for Gastroesophageal Reflux Disease

9 locations incl. Orange

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03853772·Enrolling By Invitation

Sensory-Motor Rehabilitation Post Stroke

for Acute Stroke

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 80

Code: NCT02369770·Recruiting

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Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis

for Milk and/or Peanut Allergy

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 21

Code: NCT03835767·Phase 2·Recruiting

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Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

for Peripheral T-cell Lymphomas

2 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT03922724·Phase 2·Recruiting

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Safety and Immunogenicity of Ad4-HIV Envelope Vaccine Vectors in Healthy Volunteers

for Healthy Volunteer

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03878121·Phase 1·Recruiting

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Children and Adults With Chordoma

for Chordoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+

Code: NCT03910465·Recruiting

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An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample

for Stress Disorders, Post-Traumatic

3 locations incl. Honolulu

Sponsor: U.S. Army Medical Research and Development Command

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04180930·Recruiting

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Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

for Locally Advanced Pancreatic Cancer

2 locations incl. Washington D.C.

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 75

Code: NCT03652428·Phase 1, Phase 2·Recruiting

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An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

for Hyperkalaemia

14 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 0 - 18

Code: NCT03813407·Phase 3·Recruiting

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Longitudinal Studies of Patient With FPDMM

for Inherited Hematological Diseases

1 location in Bethesda

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Day - 100·Accepts healthy volunteers

Code: NCT03854318·Recruiting

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Men at High Genetic Risk for Prostate Cancer

for Prostatic Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 30 - 75

Code: NCT03805919·Recruiting

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Study of Endocrine-Related Conditions and Physiology

for Endocrine Disease

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 90

Code: NCT03867448·Recruiting

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Perception, Sensation, Cognition and Action in Humans

for Normal Physiology

2 locations incl. Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 13 - 65·Accepts healthy volunteers

Code: NCT03407066·Recruiting

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Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

13 locations incl. Phoenix

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting

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Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1

for Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+

Code: NCT03830229·Recruiting

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

18 locations incl. Gilbert

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting

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Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

for Cushing Disease

1 location in Bethesda

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sex: All·Age: 2 - 90·Accepts healthy volunteers

Code: NCT03831958·Recruiting

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Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

for Severe Aplastic Anemia (SAA)

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 4 - 75

Code: NCT03520647·Phase 2·Recruiting

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

1229 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting

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Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank

for Pain

2 locations incl. San Diego

Sponsor: Defense and Veterans Center for Integrative Pain Management

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT04004286·Recruiting

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Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System

for Pleural Effusion

5 locations incl. Arlington Heights

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT03831386·Recruiting

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Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

for Malignant Solid Tumors

3 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT03739827·Recruiting

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Study of NEO-201 in Solid Tumors Expansion Cohorts

for Non Small Cell Lung Cancer

2 locations incl. Bethesda

Sponsor: Precision Biologics, Inc

Sex: All·Age: 18+

Code: NCT03476681·Phase 1, Phase 2·Recruiting

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Vaginal Cuff Brachytherapy Fractionation Study

for Endometrial Cancer

3 locations incl. Baltimore

Sponsor: Kara Romano, MD

Sex: Female·Age: 18+

Code: NCT03785288·Phase 3·Recruiting

Apply to this trial

A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or Casimersen in Routine Clinical Practice

for Duchenne Muscular Dystrophy

20 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06606340·Enrolling By Invitation