Paid Clinical Trials in Maryland

Maryland has 2,889 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,889 clinical trials

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A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

for Immunodeficiency

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT05027945·Phase 2·Recruiting

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Divided or Single Exposure (DOSE) Study

for Opioid Use Disorder

1 location in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 100

Code: NCT05459402·Phase 2, Phase 3·Recruiting

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

30 locations incl. Beverly Hills

Sponsor: Fore Biotherapeutics

Sex: All·Age: 10+

Code: NCT05503797·Phase 2·Recruiting

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

101 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting

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Orexin s Role in the Neurobiology of Substance Use Disorder

for Nicotine Dependence

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05630781·Recruiting

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A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

for Primary Generalized Tonic-Clonic Seizures

59 locations incl. Mobile

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05667142·Phase 3·Recruiting

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Home Exercise for Individuals with Neurodegenerative Disease

for Neurodegenerative Diseases

1 location in Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 5 - 75·Accepts healthy volunteers

Code: NCT05443906·Recruiting

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Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

4 locations incl. Baltimore

Sponsor: Imunon

Sex: Female·Age: 18+

Code: NCT05739981·Phase 1, Phase 2·Recruiting

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A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)

61 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT05519475·Phase 2·Recruiting

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Pilot/Pivotal Study of DBS+Rehab After Stroke

for Stroke

10 locations incl. Phoenix

Sponsor: Enspire DBS Therapy, Inc.

Sex: All·Age: 21+

Code: NCT05701280·Recruiting

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A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

for Adult Growth Hormone Deficiency

29 locations incl. Phoenix

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05718570·Enrolling By Invitation

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

for AMCI - Amnestic Mild Cognitive Impairment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 55+

Code: NCT05282550·Phase 2·Recruiting

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Defining Neurobiological Links Between Substance Use and Mental Illness

for Major Depressive Disorder

1 location in Baltimore

Sponsor: National Institute on Drug Abuse (NIDA)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT05538910·Recruiting

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Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

for Normal Physiology

1 location in Bethesda

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05604534·Recruiting

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Study of Healthy Cohort for Early Detection of Cancer

for Healthy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05193305·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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Study of Neoadjuvant PARP Inhibition Followed by Radical Prostatectomy in Patients With Unfavorable Intermediate-Risk or High-Risk Prostate Cancer With Select HRR Gene Alterations

for Prostate Cancer

6 locations incl. La Jolla

Sponsor: Rana McKay, MD

Sex: Male·Age: 18+

Code: NCT05498272·Phase 2·Recruiting

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Coronary Microvascular Disease (CMD) Registry

for Coronary Microvascular Dysfunction

3 locations incl. Washington D.C.

Sponsor: Medstar Health Research Institute

Sex: All·Age: 18+

Code: NCT05960474·Recruiting

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

785 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting

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Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

for Arrhythmogenic Right Ventricular Cardiomyopathy

8 locations incl. San Francisco

Sponsor: Tenaya Therapeutics

Sex: All·Age: 14 - 65

Code: NCT06311708·Recruiting

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MYLUNG Consortium Part 3: Observational Study

for Carcinoma, Non-Small-Cell Lung

17 locations incl. Daphne

Sponsor: US Oncology Research

Sex: All·Age: 18+

Code: NCT05885698·Recruiting

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Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

for Solid Tumor

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT05585684·Recruiting

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Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

for HIV

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 120·Accepts healthy volunteers

Code: NCT05470491·Phase 1, Phase 2·Recruiting

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Study of Gastric Motility in Eosinophilic Gastritis

for Eosinophilic Gastritis

3 locations incl. Chicago

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 18 - 59

Code: NCT05229432·Recruiting

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Prebiotic Treatment in People With Schizophrenia

for Schizophrenia

1 location in Catonsville

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 60

Code: NCT05527210·Recruiting

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Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for Barretts Esophagus With Dysplasia

23 locations incl. Los Angeles

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05753748·Recruiting

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A Study to See Iftolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old withAutosomal Recessive Polycystic Kidney Disease (ARPKD)

for Autosomal Recessive Polycystic Kidney (ARPKD)

12 locations incl. Washington D.C.

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 28 Days - 18

Code: NCT04782258·Phase 3·Recruiting

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Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

for Insulin Receptor Mutation

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 18 - 70

Code: NCT05470504·Phase 2·Recruiting

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A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

for Movement Disorders

4 locations incl. Baltimore

Sponsor: InSightec

Sex: All·Age: 30 - 99

Code: NCT05539196·Recruiting

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ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

for H3 K27M

67 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: All ages

Code: NCT05580562·Phase 3·Recruiting

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Gender Related Coping and Survivorship for Genitourinary Cancers

for Bladder Cancer

2 locations incl. Washington D.C.

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT05649306·Recruiting

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Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis

for Post-ERCP Acute Pancreatitis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05252754·Phase 3·Recruiting

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Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata

for Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (Apeced)

Drug: Ruxolitinib

1 location in Bethesda

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 - 75·Accepts healthy volunteers

Code: NCT05398809·Phase 2·Recruiting

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

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Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

for HER2-negative Breast Cancer

3 locations incl. Bethesda

Sponsor: The Methodist Hospital Research Institute

Sex: All·Age: 18+

Code: NCT05660083·Phase 2·Recruiting

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Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies

for Myelodysplastic Syndromes

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05588154·Recruiting

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Risk Indicators of Sarcoidosis Evolution-Unified Protocol

for Sarcoidosis, Pulmonary

2 locations incl. Baltimore

Sponsor: University of California, San Francisco

Sex: All·Age: 19+

Code: NCT05567133·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. San Francisco

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

Imaging and Biopsy of People With HIV-1 Undergoing Analytic Treatment Interruption

for HIV

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 100

Code: NCT05419024·Phase 2·Recruiting

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Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers

for Diabetic Foot

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05579743·Recruiting

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