Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,602 clinical trials

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Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

for Hormone Receptor-positive Breast Cancer

7 locations incl. New Haven

Sponsor: Ellipses Pharma

Sex: Female·Age: 18+

Code: NCT05573126·Phase 1, Phase 2·Recruiting

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Changes of Soft Tissue Grafting: A Randomized Study

for Gingival Recession

1 location in Boston

Sponsor: Tufts University

Sex: All·Age: 18+

Code: NCT05633511·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

Training in Evidence-based Treatments in Psycho-Oncology

for Distress, Emotional

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05674357·Recruiting

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

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Cognitive Processing Therapy (CPT) Memory Support (MS) Study

for PTSD

1 location in Jamaica Plain

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT05310097·Recruiting

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A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

18 locations incl. Loma Linda

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05592626·Phase 1, Phase 2·Recruiting

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AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

13 locations incl. Little Rock

Sponsor: REGENXBIO Inc.

Sex: Male·Age: 1+

Code: NCT05693142·Phase 2, Phase 3·Recruiting

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The Actuate-CBC Study

for Telemedicine

4 locations incl. Orange

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05917652·Recruiting

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

12 locations incl. Orange

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting

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Three-dimensional (3D) Printed Hemodialysis Vascular Model

for Hemodialysis Access Failure

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05096416·Not Yet Recruiting

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

for Non Small Cell Lung Cancer

4 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 15+

Code: NCT05265429·Recruiting

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Testing Effects of Melatonin on Uterine Contractions in Women

for Pregnant Women

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05358834·Recruiting

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Investigating Hereditary Risk In Thoracic Cancers (INHERIT)

for Lung Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05587439·Recruiting

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The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

for Glioblastoma

2 locations incl. San Francisco

Sponsor: Jasper Gerritsen

Sex: All·Age: 18 - 90

Code: NCT06146725·Recruiting

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The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)

for Glioblastoma

2 locations incl. San Francisco

Sponsor: Jasper Gerritsen

Sex: All·Age: 18 - 90

Code: NCT06146738·Recruiting

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The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

for Glioblastoma, IDH-wildtype

2 locations incl. San Francisco

Sponsor: Erasmus Medical Center

Sex: All·Age: Up to 90

Code: NCT06273176·Recruiting

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The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

for Glioblastoma

2 locations incl. San Francisco

Sponsor: Jasper Gerritsen

Sex: All·Age: 18 - 90

Code: NCT06283927·Recruiting

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Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

for Schizophrenia Spectrum and Other Psychotic Disorders

6 locations incl. Hartford

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 40

Code: NCT06740383·Recruiting

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JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

for Patellar Dislocation, Recurrent

16 locations incl. Redwood City

Sponsor: Hospital for Special Surgery, New York

Sex: All·Age: 10 - 35

Code: NCT06883396·Recruiting

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Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

for Hematologic Malignancy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05646576·Recruiting

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Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

for Hereditary Angioedema

13 locations incl. Birmingham

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT05396105·Phase 2, Phase 3·Enrolling By Invitation

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

for Obesity

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 9 - 12·Accepts healthy volunteers

Code: NCT05464186·Recruiting

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

30 locations incl. La Jolla

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting

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Metastatic Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

9 locations incl. Santa Monica

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT05653388·Recruiting

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Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies

for Castrate Resistant Prostate Cancer

6 locations incl. Phoenix

Sponsor: Epigenetix, Inc.

Sex: All·Age: 18+

Code: NCT05488548·Phase 1·Recruiting

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Impella ECP Study (ECP Study) and Impella ECP Continued Access Protocol

for High-Risk Percutaneous Coronary Intervention

32 locations incl. Phoenix

Sponsor: Abiomed Inc.

Sex: All·Age: 18 - 90

Code: NCT05334784·Enrolling By Invitation

Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

68 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting

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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

for Ulcerative Colitis

20 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT05287126·Phase 2·Recruiting

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Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

for Primary Aldosteronism

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 85

Code: NCT05030545·Phase 4·Recruiting

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Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF IV

for Atrial Fibrillation

2 locations incl. Jacksonville

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT05236556·Enrolling By Invitation

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

for Alzheimer Disease

1 location in Cambridge

Sponsor: Massachusetts Institute of Technology

Sex: All·Age: 65 - 100·Accepts healthy volunteers

Code: NCT05655195·Recruiting

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Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

68 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

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Multimodal Musical Stimulation for Healthy Neurocognitive Aging

for Aging

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 18 - 95·Accepts healthy volunteers

Code: NCT06229093·Recruiting

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Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for High Grade Epithelial Ovarian Cancer

37 locations incl. Phoenix

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05579366·Phase 1, Phase 2·Recruiting

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BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

for Clinical Stage III Cutaneous Melanoma AJCC v8

Drug: Cabozantinib

222 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05136196·Phase 2·Recruiting

Apply to this trial