Supporting Use of AC Through Provider Profiling of Oral AC Therapy for AF IV
Part of paid clinical trials in Jacksonville, Florida.
- Sponsor
- University of Massachusetts, Worcester
- Study ID
- NCT05236556
- Status
- Enrolling By Invitation
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Best practice advisory (BPA) — BEHAVIORALFor patients who are not on oral anticoagulation (AC) but have elevated stroke risk, the practice advisory will "fire," which is to say it will be active in the providers workflow during outpatient encounters with a patient's primary care provider (PCP) or cardiology provider.
Study Details
Six million Americans live with atrial fibrillation (AF), a heart rhythm abnormality that is a major risk factor for stroke and only half of those AF patients receive oral anticoagulation (AC). Within the context of an ongoing collaboration between two large learning health systems, the investigators propose to study the impact of a shared clinical decision support tool embedded within the electronic health record designed to enhance guideline-based AC prescription. The hypothesis the investigators are testing is that the number of AC starts in patients seen by intervention providers will be higher than in patients seen by control providers. Additionally, the investigators are testing the hypothesis that the risk of not persisting on AC will be higher in the patients of control providers compared with patients of intervention providers.
Key Dates
- Start date
- Dec 15, 2022
- Status verified
- Mar 2026
- Primary completion
- Dec 31, 2027
- Completion
- Jun 30, 2028
Study Design
- Enrollment
- 5,094 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: InterventionReceive best practice advisory (BPA)
- No Intervention: ControlDoes not receive best practice advisory (BPA)
Primary Outcome Measure
Initiation of Oral Anticoagulation (AC) Use [ Time Frame: 12 months ]
Locations (2)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Florida College of Medicine - Jacksonville | Jacksonville | Florida | 32209 | - |
| UMass Chan Medical School | Worcester | Massachusetts | 01655 | - |
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