Paid Clinical Trials in Massachusetts

Massachusetts has 3,587 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,587 clinical trials

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Wearable Spine Assessment in Adults With and Without Low Back or Neck Pain

for Low Back Pain

1 location in Newton

Sponsor: Ashkan Vaziri

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07643207·Not Yet Recruiting

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

for HIV-1-infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06987318·Phase 1·Not Yet Recruiting

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria

for Proteinuric Renal Disease

Drug: Sparsentan

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07224776·Phase 1·Not Yet Recruiting

A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder

for Borderline Personality Disorder (BPD)

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18+

Code: NCT07460947·Phase 1, Phase 2·Recruiting

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Determination 2 - Isatuximab, Iberdomide, Bortezomib and Dexamethasone Induction, Followed by Risk- and Response-Adapted Consolidation and Maintenance Therapy, in Transplant-Eligible Patients With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Iberdomide

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT07624513·Phase 3·Not Yet Recruiting

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for Advanced Clear Cell Renal Cell Carcinoma

41 locations incl. Fayetteville

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT07383441·Phase 3·Recruiting

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A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement

for FGFR2 Gene Fusion/Rearrangement

Drug: Lirafugratinib

7 locations incl. Phoenix

Sponsor: Elevar Therapeutics

Sex: All·Age: 18+

Code: NCT07359820·Phase 2·Recruiting

Apply to this trial

GBPDC: Gut-Brain in PD Consortium Master Protocol

for Parkinson Disease (PD)

7 locations incl. Stanford

Sponsor: Duke University

Sex: All·Age: 21 - 80·Accepts healthy volunteers

Code: NCT07567794·Not Yet Recruiting

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

for Persistent Corneal Epithelial Defect

18 locations incl. Huntington Beach

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 18+

Code: NCT07519902·Phase 3·Recruiting

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A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies

for HIV

4 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60

Code: NCT07569029·Phase 1·Not Yet Recruiting

Effects of taVNS on Fibromyalgia Pain

for Fibromyalgia, Pain

1 location in Cambridge

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18+

Code: NCT06193317·Not Yet Recruiting

Impact of a Virtual Reality-based Mindfulness Program on Clinician Wellness

for Wellness, Psychological

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06246539·Not Yet Recruiting

Prediction Augmented Screening Initiative

for Lung Cancer

4 locations incl. Bedford

Sponsor: VA Office of Research and Development

Sex: All·Age: 50 - 80

Code: NCT06538636·Not Yet Recruiting

Subconjunctival Humira for Boston Keratoprosthesis

for Penetrating Keratoplasty

1 location in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 18+

Code: NCT06926478·Phase 1·Not Yet Recruiting

Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

for Atrial Fibrillation

1 location in Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT06953726·Phase 4·Not Yet Recruiting

A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

for Myopia

12 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 5 - 11

Code: NCT07095894·Phase 3·Recruiting

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A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: Up to 18

Code: NCT07192952·Phase 3·Recruiting

Apply to this trial

Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure

for Heart Failure

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 85

Code: NCT07337577·Not Yet Recruiting

Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?

for Amyotrophic Lateral Sclerosis (ALS)

7 locations incl. Scottsdale

Sponsor: Trustees of Dartmouth College

Sex: All·Age: 18+

Code: NCT07454733·Not Yet Recruiting

Readiness Outcomes Affecting Return to Sport 3.0

for ACL Reconstruction

1 location in Waltham

Sponsor: Boston Children's Hospital

Sex: All·Age: 8 - 25

Code: NCT07476430·Not Yet Recruiting

Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy

for Achilles Injuries Tendon

1 location in Cambridge

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 65

Code: NCT07483320·Not Yet Recruiting

A Study of JZP3507 (ONC206) in Recurrent Grade 2 or 3 Meningioma

for Meningioma

Drug: JZP3507

5 locations incl. San Francisco

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07533942·Phase 2·Not Yet Recruiting

PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels

for Amyloidogenic Transthyretin (ATTR) Amyloidosis

3 locations incl. Boston

Sponsor: Lorena Saelices

Sex: All·Age: All ages

Code: NCT07538518·Not Yet Recruiting

Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth

for Dyslipidemia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 2 - 17

Code: NCT07545005·Not Yet Recruiting

Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence

for Prostate Cancer

6 locations incl. San Diego

Sponsor: Blue Earth Diagnostics

Sex: Male·Age: 18+

Code: NCT07569926·Phase 4·Not Yet Recruiting

Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 79

Code: NCT07577661·Phase 1, Phase 2·Not Yet Recruiting

HIPS Feasibility Randomized Controlled Trial

for Hip Pain Chronic

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07586397·Not Yet Recruiting

Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea

for Rosacea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07600424·Not Yet Recruiting

PROspect Registry :Post Market Clinical Follow-up Study

for Breast Surgery

1 location in Boston

Sponsor: Stryker Endoscopy

Sex: All·Age: 18+

Code: NCT07631468·Not Yet Recruiting

Uterine Transplant in Absolute Uterine Infertility (AUIF)

for Female Infertility

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 40

Code: NCT02741102·Phase 2, Phase 3·Recruiting

Apply to this trial

Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)

for Infertility of Uterine Origin

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT04026893·Recruiting

Apply to this trial

Early Intervention

for Breast Cancer

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT05326165·Not Yet Recruiting

Integrated Smartphone Technology to Alleviate Malignant Pain (I-STAMP) Testing

for Advanced Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 21+

Code: NCT06117709·Not Yet Recruiting

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

for Prostate Cancer (Adenocarcinoma)

2 locations incl. Boston

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 18+

Code: NCT06844383·Phase 2·Recruiting

Apply to this trial

REducing pSychological diSTress To Optimize Recovery of Elderly ICU Survivors and Caregivers (RESTORE-ICU)

for Relationship, Family

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06867367·Not Yet Recruiting

Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD

for NMOSD

Drug: Inebilizumab

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07010302·Phase 4·Not Yet Recruiting

A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship

for Lymphoma

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07013435·Not Yet Recruiting

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

for Breast Neoplasms

25 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07287098·Phase 2·Not Yet Recruiting

The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Injury

for Caregiver Distress

3 locations incl. Baltimore

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07331324·Not Yet Recruiting

Vitamin D and Type 2 Diabetes - Treat-To-Target

for Prediabetes

1 location in Boston

Sponsor: Tufts Medical Center

Sex: All·Age: 30 - 74

Code: NCT07448974·Phase 3·Not Yet Recruiting