Brain Outcomes With Lifestyle Change in Down Syndromefor Down Syndrome1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 18 - 64Code: NCT05985486·RecruitingApply to this trial
Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMITfor Duchenne Muscular Dystrophy25 locations incl. PhoenixSponsor: Catalyst Pharmaceuticals, Inc.Sex: Male·Age: 2+Code: NCT06564974·RecruitingApply to this trial
Rural Alliance for Diabetes Preventionfor PreDiabetes1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 18+Code: NCT06252038·RecruitingApply to this trial
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulatorsfor Cystic Fibrosis68 locations incl. BirminghamSponsor: Nicole HamblettSex: All·Age: 12+Code: NCT06504589·RecruitingApply to this trial
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosisfor Metabolic Dysfunction Associated Steatohepatitis (MASH)Drug: Survodutide165 locations incl. BirminghamSponsor: Boehringer IngelheimSex: All·Age: 18+Code: NCT06632444·Phase 3·RecruitingApply to this trial
A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)for Cystic Fibrosis4 locations incl. Kansas CitySponsor: Spirovant Sciences, Inc.Sex: All·Age: 18 - 65Code: NCT06526923·Phase 1, Phase 2·RecruitingApply to this trial
Fast Induced Remodeling in Heart Failure With Preserved Ejection Fractionfor Heart Failure With Preserved Ejection Fraction8 locations incl. NaplesSponsor: Medtronic Cardiac Rhythm and Heart FailureSex: All·Age: 18+Code: NCT05839730·RecruitingApply to this trial
PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.for Androgen Axis SuppressionDrug: Apalutamide5 locations incl. ChicagoSponsor: M.D. Anderson Cancer CenterSex: Male·Age: 18+Code: NCT06274047·Phase 3·RecruitingApply to this trial
Blood Flow Restriction Following ACLR w/Quad Autograftfor Autografts1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 14 - 40Code: NCT06636045·Enrolling By Invitation
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)for Kidney Disease, ChronicDrug: Empagliflozin41 locations incl. HuntsvilleSponsor: Boehringer IngelheimSex: All·Age: 18+Code: NCT06531824·Phase 3·RecruitingApply to this trial
A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)for Chronic Inflammatory Demyelinating PolyneuropathyDrug: riliprubart29 locations incl. HomewoodSponsor: SanofiSex: All·Age: 18+Code: NCT06290141·Phase 3·RecruitingApply to this trial
Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetesfor Osteoarthritis, Knee1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 40+Code: NCT06478186·Phase 4·RecruitingApply to this trial
Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosisfor Multiple Sclerosis1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 18 - 65Code: NCT06428006·Phase 2·RecruitingApply to this trial
A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)for Generalized Myasthenia GravisDrug: Telitacicept20 locations incl. Los AngelesSponsor: Vor BiopharmaSex: All·Age: 18+Code: NCT06456580·Phase 3·RecruitingApply to this trial
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Workfor Chronic Inflammatory Demyelinating PolyradiculoneuropathyDrug: riliprubart27 locations incl. HomewoodSponsor: SanofiSex: All·Age: 18+Code: NCT06290128·Phase 3·RecruitingApply to this trial
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Painfor Degenerative Disc Disease39 locations incl. PhoenixSponsor: Mesoblast, Ltd.Sex: All·Age: 18+Code: NCT06325566·Phase 3·RecruitingApply to this trial
Continuation Protocol for Obstructive Sleep Apnea (OSA)for OSA93 locations incl. BirminghamSponsor: ApnimedSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06566820·Phase 3·Enrolling By Invitation
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosisfor Systemic Sclerosis10 locations incl. New HavenSponsor: Cabaletta BioSex: All·Age: 18 - 75Code: NCT06328777·Phase 1, Phase 2·RecruitingApply to this trial
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorderfor Methamphetamine-dependence11 locations incl. Little RockSponsor: National Institute on Drug Abuse (NIDA)Sex: All·Age: 18 - 65Code: NCT06233799·Phase 3·RecruitingApply to this trial
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)for Ulcerative ColitisDrug: Tofacitinib40 locations incl. DothanSponsor: TakedaSex: All·Age: 18 - 65Code: NCT06095128·Phase 4·RecruitingApply to this trial
Effect of Adult Spinal Deformity Surgery on Functional Reachfor Scoliosis1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06258161·RecruitingApply to this trial
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)for Crohn's DiseaseDrug: Tulisokibart87 locations incl. DothanSponsor: Merck Sharp & Dohme LLCSex: All·Age: 16 - 80Code: NCT06430801·Phase 3·RecruitingApply to this trial
Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis.for Cystic Fibrosis1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 12+Code: NCT06364176·Phase 2·RecruitingApply to this trial
Health Outcomes of Parents With Cystic Fibrosis-Aim 2for Cystic Fibrosis18 locations incl. BirminghamSponsor: University of PittsburghSex: All·Age: 18+Code: NCT06296394·RecruitingApply to this trial
Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Devicefor Degenerative Conditions of the Lumbar Spine6 locations incl. NewnanSponsor: Spinal Simplicity LLCSex: All·Age: 18+Code: NCT06355791·RecruitingApply to this trial
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancerfor Non-small Cell Lung Cancer22 locations incl. BirminghamSponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)Sex: All·Age: 18+Code: NCT06343402·Phase 1·RecruitingApply to this trial
VE303 for Prevention of Recurrent Clostridioides Difficile Infectionfor Clostridium Difficile84 locations incl. HuntsvilleSponsor: Vedanta Biosciences, Inc.Sex: All·Age: 12+Code: NCT06237452·Phase 3·RecruitingApply to this trial
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trialfor Acute Ischemic Stroke51 locations incl. MobileSponsor: Mercy Health OhioSex: All·Age: 18 - 79Code: NCT05611242·Phase 3·RecruitingApply to this trial
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilastfor Idiopathic Pulmonary FibrosisDrug: Nerandomilast58 locations incl. BirminghamSponsor: Boehringer IngelheimSex: All·Age: 18+Code: NCT06238622·Phase 3·RecruitingApply to this trial
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Diseasefor Crohn's DiseaseDrug: Ustekinumab45 locations incl. DothanSponsor: TakedaSex: All·Age: 18 - 70Code: NCT06045754·Phase 4·RecruitingApply to this trial
IMPRoving Outcomes in Vascular DisEase - Aortic Dissectionfor Type B Aortic Dissection61 locations incl. BirminghamSponsor: Duke UniversitySex: All·Age: 21+Code: NCT06087029·RecruitingApply to this trial
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adultsfor Brain Aging1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 65 - 85·Accepts healthy volunteersCode: NCT06137339·RecruitingApply to this trial
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)for Multiple Sclerosis17 locations incl. BirminghamSponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanySex: All·Age: 18 - 60Code: NCT06220201·Phase 1·RecruitingApply to this trial
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Diseasefor Crohn's DiseaseDrug: TAK-27929 locations incl. Los AngelesSponsor: TakedaSex: All·Age: 18 - 75Code: NCT06233461·Phase 2·RecruitingApply to this trial
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Agingfor Exercise Training1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 45 - 65·Accepts healthy volunteersCode: NCT06123182·RecruitingApply to this trial
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosusfor Systemic Lupus Erythematosus21 locations incl. OrangeSponsor: Cabaletta BioSex: All·Age: 18 - 65Code: NCT06121297·Phase 1, Phase 2·RecruitingApply to this trial
HIT-Stroke Trial 2for Stroke3 locations incl. NewarkSponsor: University of CincinnatiSex: All·Age: 30 - 85Code: NCT06268041·RecruitingApply to this trial
An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophyfor Duchenne Muscular Dystrophy25 locations incl. Little RockSponsor: Sarepta Therapeutics, Inc.Sex: Male·Age: 4+Code: NCT06270719·Enrolling By Invitation
To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivorsfor Stroke1 location in Kansas CitySponsor: University of Kansas Medical CenterSex: All·Age: 18 - 80Code: NCT06247553·RecruitingApply to this trial
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenTfor Hypertension70 locations incl. ScottsdaleSponsor: Orchestra BioMed, IncSex: All·Age: 18+Code: NCT06059638·RecruitingApply to this trial