Clinical Trials at University of Iowa

As of June 2026, 210 paid clinical trials are recruiting at University of Iowa, located at 200 HAWKINS DR, IOWA CITY, IA 52242, phone (319) 356-1616 in Iowa City, Iowa. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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210 clinical trials at University of Iowa

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Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

for COPD Acute Exacerbation

22 locations incl. Birmingham

Sponsor: Connect Biopharm LLC

Sex: All·Age: 40 - 80

Code: NCT06940154·Phase 2·Recruiting

Apply to this trial

Rademikibart Add-on Treatment of an Acute Asthma Exacerbation (Seabreeze STAT Asthma)

for Asthma Acute

18 locations incl. Palo Alto

Sponsor: Connect Biopharm LLC

Sex: All·Age: 12 - 75

Code: NCT06940141·Phase 2·Recruiting

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

11 locations incl. Birmingham

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting

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A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease

for Fabry Disease

6 locations incl. Phoenix

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 2 - 17

Code: NCT06328608·Phase 2, Phase 3·Recruiting

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A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

for Colon Adenocarcinoma

Drug: Calderasib

26 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06997497·Phase 3·Recruiting

Apply to this trial

SMBP Study: Improving High Blood Pressure in Older Adults With Multiple Chronic Diseases

for Hypertension

2 locations incl. Iowa City

Sponsor: Korey Kennelty

Sex: All·Age: 65+

Code: NCT06932029·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

15 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06994806·Phase 1·Recruiting

Apply to this trial

Effect of Custom Dynamic Orthoses on Forefoot Loading

for Lower Extremity Injuries

2 locations incl. Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 65

Code: NCT06710119·Recruiting

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Neonatal Platelet Transfusion Threshold Trial

for Thrombocytopenia

20 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 1 Hour - 48 Hours·Accepts healthy volunteers

Code: NCT06676904·Recruiting

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Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

for Post-ligation Cardiac Syndrome

19 locations incl. Birmingham

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 3 Months

Code: NCT06679855·Phase 3·Recruiting

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A Study to Evaluate Del-brax (Also Referred to as AOC 1020) in Participants With FSHD

for Facioscapulohumeral Muscular Dystrophy

14 locations incl. Orange

Sponsor: Avidity Biosciences, Inc.

Sex: All·Age: 16 - 70

Code: NCT07038200·Phase 3·Recruiting

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ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

for Autosomal Dominant Polycystic Kidney Disease

35 locations incl. Garden Grove

Sponsor: Calico Life Sciences LLC

Sex: All·Age: 18 - 55

Code: NCT06902558·Phase 2·Recruiting

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Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

for Leber Congenital Amaurosis 10

5 locations incl. San Francisco

Sponsor: Laboratoires Thea

Sex: All·Age: 6+

Code: NCT06891443·Phase 3·Recruiting

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Motor Outcomes to Validate Evaluations in Pediatric FSHD (MOVE Peds)

for Muscular Dystrophy, Facioscapulohumeral

6 locations incl. Palo Alto

Sponsor: University of Kansas Medical Center

Sex: All·Age: 5 - 17

Code: NCT06847282·Recruiting

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Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

for Sensorineural Hearing Loss

3 locations incl. Englewood

Sponsor: Cochlear

Sex: All·Age: 18+

Code: NCT06936449·Recruiting

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A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

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Chronic Lung Allograft Dysfunction MRI Study

for Chronic Lung Allograft Dysfunction Lung MRI (CLAD)

1 location in Iowa City

Sponsor: Sean Fain

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06406777·Phase 1, Phase 2·Recruiting

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Barriers and Facilitators to OTC Hearing Aids Success

for Hearing Loss, Sensorineural

2 locations incl. Iowa City

Sponsor: Yu-Hsiang Wu

Sex: All·Age: 18 - 89

Code: NCT06499805·Recruiting

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Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers

for Nephrolithiasis

1 location in Iowa City

Sponsor: Ryan L Steinberg

Sex: All·Age: 18 - 90

Code: NCT06974357·Recruiting

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Aquagenic Wrinkling Prediction

for Aquagenic Wrinkling of Palms

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT06831110·Recruiting

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Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

MB-105 in Patients With CD5 Positive T-cell Lymphoma

for Lymphoma, T-Cell

12 locations incl. San Diego

Sponsor: March Biosciences Inc

Sex: All·Age: 18+

Code: NCT06534060·Phase 2·Recruiting

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Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

for Systemic Sclerosis (SSc)

6 locations incl. La Jolla

Sponsor: Zura Bio Inc

Sex: All·Age: 18 - 75

Code: NCT06843239·Phase 2·Recruiting

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A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

for SLE

10 locations incl. Avondale

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT06613360·Phase 1·Recruiting

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Vascular Effects of High-Salt After Preeclampsia

for Preeclampsia

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06749418·EARLY_Phase 1·Recruiting

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Nivolumab

29 locations incl. Scottsdale

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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Study of 68Ga-R10602

for Locoregionally Recurrent Hormone-receptor Positive Breast Cancer

6 locations incl. Los Angeles

Sponsor: Radionetics Oncology

Sex: All·Age: 18+

Code: NCT06745804·Phase 1·Recruiting

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A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

24 locations incl. Chula Vista

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

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Ankle Fracture Tourniquet Utilization

for Ankle Fracture

1 location in Iowa City

Sponsor: Alex Demers

Sex: All·Age: 18 - 65

Code: NCT06863688·Enrolling By Invitation

A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

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Cochlear Implant Speech in Noise Processing

for Hearing Loss, Adult-Onset

1 location in Iowa City

Sponsor: Craig D. Workman, PhD

Sex: All·Age: 18 - 99

Code: NCT06860152·Recruiting

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Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

for Otoferlin Gene-mediated Hearing Loss

3 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT06696456·Enrolling By Invitation

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

17 locations incl. San Francisco

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting

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Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

14 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting

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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for Peripheral T-Cell Lymphoma, Not Otherwise Specified

Drug: Soquelitinib

21 locations incl. Duarte

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06561048·Phase 3·Recruiting

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Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06547619·EARLY_Phase 1·Recruiting

Apply to this trial