Aquagenic Wrinkling Prediction

Part of paid clinical trials in Iowa City, Iowa.

Sponsor
University of Iowa
Study ID
NCT06831110
Status
Recruiting
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Conditions

  • Aquagenic Wrinkling of Palms
  • Carrier State

Eligibility Criteria

Sex
ALL
Age
18 Years - 24 Years
Healthy Volunteers
Accepted

Interventions

  • Aquagenic Wrinkling — PROCEDURE
    Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water.

Study Details

The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status. Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.

Key Dates

Start date
Mar 6, 2025
Status verified
Jun 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
2,000 participants (estimated)

Arms

  • Arm: Potential Cystic Fibrosis Carriers
    Participants that are identified as potential cystic fibrosis carriers based on aquagenic wrinkling results.
  • Arm: Potential Controls
    Participants that are identified as potential controls based on aquagenic wrinkling results.

Primary Outcome Measure

Human Observation of Wrinkling [ Time Frame: Up to 20 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of IowaIowa CityIowa52242
Shelby Francis, PhD
[email protected]
319-678-8037

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By research site
University of Iowa· Iowa City, IA

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