Paid Clinical Trials in Iowa

Iowa has 822 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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822 clinical trials

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The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

for Adverse Childhood Experiences

1 location in Iowa City

Sponsor: Nathaniel Jenkins

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT06454344·Recruiting

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

134 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting

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A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

for Atrial Fibrillation

35 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06335082·Enrolling By Invitation

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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Concurrent TMS-fMRI

for Healthy Control

1 location in Iowa City

Sponsor: Jing Jiang

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06633913·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

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Empagliflozin Treatment in Kidney Transplant Recipients

for Kidney Transplant

Drug: Empagliflozin

5 locations incl. Hines

Sponsor: VA Office of Research and Development

Sex: All·Age: 19+

Code: NCT06013865·Phase 4·Recruiting

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Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

for Acne

79 locations incl. Scottsdale

Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All·Age: 18 - 45

Code: NCT06316297·Phase 1, Phase 2·Recruiting

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Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe

for Ischemic Stroke

4 locations incl. Atlanta

Sponsor: Raul Nogueira

Sex: All·Age: 18+

Code: NCT05983757·Recruiting

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Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

44 locations incl. Homewood

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

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Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy

46 locations incl. Alabaster

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06291376·Phase 3·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

104 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

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The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

for Polycystic Ovary Syndrome

24 locations incl. Encino

Sponsor: May Health

Sex: Female·Age: 18 - 40

Code: NCT06206746·Recruiting

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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

36 locations incl. Jonesboro

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma

for Cutaneous Melanoma

Drug: Avutometinib

2 locations incl. Iowa City

Sponsor: University of Utah

Sex: All·Age: 18+

Code: NCT06194929·Phase 1, Phase 2·Recruiting

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VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

for Crohn's Disease

12 locations incl. Sun City

Sponsor: Alimentiv Inc.

Sex: All·Age: 18+

Code: NCT06249555·Recruiting

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

52 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting

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Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19

for Long COVID

3 locations incl. Iowa City

Sponsor: MaxWell Clinic, PLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06311435·Recruiting

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A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

for Focal Epilepsy

Drug: BHV-7000

61 locations incl. Phoenix

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06132893·Phase 2, Phase 3·Recruiting

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A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

141 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

41 locations incl. Fayetteville

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting

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OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

for Hyperphagia in Prader-Willi Syndrome

19 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 5 - 30

Code: NCT06420297·Phase 3·Enrolling By Invitation

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

124 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: TAK-279

29 locations incl. Los Angeles

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

133 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting

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Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

for Healthy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06127264·Recruiting

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

20 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting

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Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

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Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

for Malignant Solid Neoplasm

384 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06295367·Recruiting

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Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

for Early Breast Cancer

Drug: Ribociclib

78 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05827081·Phase 3·Recruiting

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Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

for AML

38 locations incl. Gilbert

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06001788·Phase 1·Recruiting

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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

34 locations incl. Little Rock

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

234 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting

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Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer

for Metastatic Nasopharyngeal Carcinoma

Drug: Cabozantinib

92 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05904080·Phase 2·Recruiting

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Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

for Coronary Artery Disease

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 80

Code: NCT06207318·Recruiting

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A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

Drug: Avacopan

60 locations incl. Anchorage

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT06072482·Phase 4·Recruiting

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Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

for Follicular Lymphoma (FL)

Drug: Epcoritamab

58 locations incl. Fresno

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT06191744·Phase 3·Recruiting

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Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

for Muscle Invasive Bladder Urothelial Carcinoma

490 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05987241·Phase 2, Phase 3·Recruiting

Apply to this trial