Paid Clinical Trials in Houston, TX

As of June 2026, 3,160 paid clinical trials are recruiting in Houston, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,160 clinical trials

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ACute Uncomplicated Type b Aortic Dissection: Endovascular Repair vs. Best Medical Therapy

for Distal Aortic Dissection

2 locations incl. Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT02622542·Recruiting

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Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

for Pancreatic Cyst

10 locations incl. Scottsdale

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT03492151·Recruiting

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The Influence of Repairing the Sub-scapularis on Outcomes After Reverse Arthroplasty

for Severe Arthropathy With a Grossly Deficient Rotator Cuff

4 locations incl. St Louis

Sponsor: Encore Medical, L.P.

Sex: All·Age: 21+

Code: NCT03711175·Enrolling By Invitation

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

50 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

334 locations incl. Gilbert

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting

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Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for Melanoma Stage IIIB

19 locations incl. Phoenix

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT03567889·Phase 3·Recruiting

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Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

for Acute Myeloid Leukemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12+

Code: NCT03589729·Phase 2·Recruiting

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Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation

for Acute Bilineal Leukemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03683433·Phase 2·Recruiting

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Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

for Malignant Oral Cavity Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04265430·Phase 4·Recruiting

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ATrial Tachycardia PAcing Therapy in Congenital Heart

for Atrial Arrhythmia

14 locations incl. Los Angeles

Sponsor: Ian Law

Sex: All·Age: All ages

Code: NCT03209583·Recruiting

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Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

15 locations incl. San Francisco

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting

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Effect of Treatment Modality on Psychosocial Functioning of Survivors of Unilateral Retinoblastoma

for Survivors of Unilateral Retinoblastoma

2 locations incl. New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 8 - 17

Code: NCT03662776·Enrolling By Invitation

The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

24 locations incl. Birmingham

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting

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Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

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Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

for ENSAT Stage I Adrenal Cortex Carcinoma

3 locations incl. Ann Arbor

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03583710·Phase 3·Recruiting

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Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma

for Anatomic Stage III Breast Cancer AJCC v8

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03941756·Recruiting

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Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

for Metastatic Urothelial Cancer

37 locations incl. Tucson

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT03547973·Phase 2·Recruiting

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APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies

for Hematologic Malignancies

3 locations incl. Jacksonville

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT03537482·EARLY_Phase 1·Recruiting

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Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

for Obstructive Sleep Apnea of Adult

14 locations incl. Birmingham

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 18+

Code: NCT03487185·Recruiting

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Complex Adult Deformity Surgery (CADS)

for Adult Spinal Deformity

17 locations incl. La Jolla

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194138·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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Self-monitoring Focus Groups With Vibrant Lives Pasadena Participants

for Obesity-Related Malignant Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04611087·Recruiting

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A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves

for Post Operative Pain

7 locations incl. Jacksonville

Sponsor: AtriCure, Inc.

Sex: All·Age: 12+

Code: NCT05110989·Recruiting

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VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

for Head and Neck Carcinoma

14 locations incl. Santa Rosa

Sponsor: VM Oncology, LLC

Sex: All·Age: 18 - 80

Code: NCT03556228·Phase 1, Phase 2·Recruiting

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Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility

for Diabetes Mellitus

1 location in Houston

Sponsor: Hamad Medical Corporation

Sex: All·Age: 40+

Code: NCT05407207·Recruiting

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Natural History Study and Establishment of a Biorepository-TANGO2-related Disorder

for TANGO2-related Disorder

1 location in Houston

Sponsor: Baylor College of Medicine

Sex: All·Age: 0 Days+

Code: NCT05374616·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

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Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

for Acral Lentiginous Melanoma

Drug: Nivolumab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03025256·Phase 1·Recruiting

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A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

23 locations incl. La Jolla

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT03526835·Phase 1, Phase 2·Recruiting

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Longitudinal Early-onset Alzheimer's Disease Study Protocol

for Early Onset Alzheimer Disease

18 locations incl. Sun City

Sponsor: Indiana University

Sex: All·Age: 40 - 64·Accepts healthy volunteers

Code: NCT03507257·Recruiting

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Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

for Neoplasms

13 locations incl. Atlanta

Sponsor: USWM CT, LLC

Sex: All·Age: All ages

Code: NCT03391778·Phase 1·Recruiting

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Houston Emergency Opioid Engagement System

for Opioid Use Disorder

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT03396276·Phase 4·Enrolling By Invitation

Pain Biomarker Study

for Migraine

1 location in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03511846·Phase 1·Enrolling By Invitation

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

for Acute Myeloid Leukemia

Drug: Venetoclax

4 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03471260·Phase 1, Phase 2·Recruiting

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Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

for Lung Carcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03422302·Recruiting

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Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

for Hematopoietic and Lymphoid Cell Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages

Code: NCT03425526·Phase 1·Recruiting

Apply to this trial

Service and Health Among Deployed Veterans

for Pulmonary Function

6 locations incl. San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT02825654·Enrolling By Invitation

Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions

for Pleural Neoplasm

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT03465774·Recruiting

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HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM

for Glioblastoma

1 location in Houston

Sponsor: The Methodist Hospital Research Institute

Sex: All·Age: 18+

Code: NCT03603405·Phase 1, Phase 2·Recruiting

Apply to this trial

The PREDICT Registry:

for DCIS

30 locations incl. Scottsdale

Sponsor: PreludeDx

Sex: Female·Age: 30 - 85

Code: NCT03448926·Recruiting

Apply to this trial