Clinical Trials at MD Anderson Cancer Center

As of June 2026, 425 paid clinical trials are recruiting at MD Anderson Cancer Center, located at 1515 HOLCOMBE BLVD, UNIT 1445, HOUSTON, TX 77030-4000, phone (713) 745-0496 in Houston, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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425 clinical trials at MD Anderson Cancer Center

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A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

for Phase 1b

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07401875·Phase 1·Recruiting

Apply to this trial

Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

5 locations incl. Boston

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting

Apply to this trial

A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies

for Acute Myeloid Leukemia, in Relapse

3 locations incl. Charlotte

Sponsor: ARCE Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT06906380·Not Yet Recruiting

Pilot Study of Aerobic Exercise During Immune Checkpoint Inhibitor Therapy in Early-Stage TNBC

for Aerobic Exercise

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07216495·Recruiting

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Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

for Acute Myeloid Leukemia

2 locations incl. New York

Sponsor: Remedy Plan, Inc.

Sex: All·Age: 18+

Code: NCT07107126·Phase 1·Recruiting

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Trial of THEO-260 (Administered Via Intraperitoneal Route) in Ovarian Cancer Patients

for Ovarian Cancer

1 location in Houston

Sponsor: Theolytics Limited

Sex: Female·Age: 18+

Code: NCT07211659·Phase 1·Recruiting

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Development of a Shared Decision Tool to Facilitate Uptake of the Levonorgestrel-releasing Intrauterine System for the Primary Prevention of Endometrial Cancer

for Levonorgestrel

2 locations incl. Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07382583·Recruiting

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A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

29 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07266441·Phase 2·Recruiting

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A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

for Multiple Myeloma (MM)

Drug: Elranatamab

16 locations incl. Gilbert

Sponsor: C4 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07280013·Phase 1·Recruiting

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Together Stronger: A Family-centered Lifestyle Intervention for Black Prostate Cancer Survivors and Their Caregivers

for Family Centered

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Male·Age: 18+

Code: NCT07164456·Recruiting

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

5 locations incl. Chicago

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting

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Pacritinib vs. Hydroxyurea in Advanced Proliferative Chronic Myelomonocytic Leukemia

for Leukemia, Myelomonocytic, Chronic

Drug: Pacritinib

4 locations incl. Tampa

Sponsor: Theradex

Sex: All·Age: 18+

Code: NCT07033598·Phase 2·Recruiting

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Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

3 locations incl. Duarte

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2·Recruiting

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A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial

for Spiritual Care

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07246954·Recruiting

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Exploring the Benefit of Topical Capsaicin in Treating Pain From Chemo-induced Peripheral Neuropathy: a Longitudinal Single Center Pilot Study

for Peripheral Neuropathy Due to Chemotherapy

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06744816·EARLY_Phase 1·Recruiting

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A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

for Locally Advanced Solid Tumor

6 locations incl. New Haven

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213817·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

41 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07276399·Phase 3·Recruiting

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

15 locations incl. Santa Monica

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting

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A Pilot Study to Correlate 4-18F- Fluoro-1-naphthol 18F-4FN PET/CT Imaging With Chronic Graft Versus Host Disease Manifestations

for Pilot Study

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07325253·Phase 2·Recruiting

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Belzutifan's Role in Active Surveillance Versus Treatment for Indolentmetastatic Clear Cell Renal Ccell Carcinoma (BRAVE-RCC)

for Active Surveillance

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07023432·Phase 2·Recruiting

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Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors

for Selected Types of Solid Tumor

3 locations incl. New York

Sponsor: Everest Medicines (Beijing) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07095868·Phase 1, Phase 2·Recruiting

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A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

for Non Small Cell Lung Cancer

11 locations incl. San Francisco

Sponsor: Rondo Therapeutics

Sex: All·Age: 18+

Code: NCT07218003·Phase 1·Enrolling By Invitation

Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules

for Thyroid Nodules

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07226804·Recruiting

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A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

10 locations incl. Los Angeles

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1·Recruiting

Apply to this trial

Actinium Therapy for Late-stage Aggressive Sarcomas

for Advanced Soft Tissue Sarcoma

5 locations incl. Los Angeles

Sponsor: Ratio Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07156565·Phase 1·Recruiting

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

14 locations incl. Aurora

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting

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A Phase 2 Platform Study of Immunomodulatory Compounds in ICI-refractory Non-small Cell Lung Cancer

for Non-Small Cell Lung Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07133425·Phase 2·Recruiting

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Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device

for Colon Cancer

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 20 - 85

Code: NCT06927011·Not Yet Recruiting

IvoLoC Trial: A Phase II Trial Evaluating the Efficacy of Ivonescimab in Metastatic Endocrine Refractory HR-positive HER2-negative or Triple Negative Invasive Lobular Carcinoma

for Metastatic Endocrine Refractory

Drug: Ivonescimab

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07229417·Phase 2·Recruiting

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A Study of ZW251 in Participants With Advanced Solid Tumors

for Hepatocellular Carcinoma

8 locations incl. San Francisco

Sponsor: Zymeworks BC Inc.

Sex: All·Age: 18+

Code: NCT07164313·Phase 1·Recruiting

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Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic Phase

for Chronic Myeloid Leukemia

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06817720·Phase 2·Recruiting

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A Study of CTD402 in T-ALL/LBL Patients

for Acute Lymphocytic Leukemia Refractory

8 locations incl. Palo Alto

Sponsor: BIOHENG THERAPEUTICS US LLC

Sex: All·Age: 12+

Code: NCT07070219·Phase 1, Phase 2·Recruiting

Apply to this trial

Evaluation of Meaning-centered Group Psychotherapy in Integrative Medicine

for Psychotherapy

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07147205·Recruiting

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A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer

for Locoregionally Recurrent Hormone-receptor Positive Breast Cancer

6 locations incl. Indianapolis

Sponsor: Radionetics Oncology

Sex: All·Age: 18+

Code: NCT07121244·Phase 1·Recruiting

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Mucormycosis Clinical Core for the MUCOR-ADVANCE P01 Project

for Mucormycosis

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18 - 100

Code: NCT06878144·Not Yet Recruiting

Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry Study

for Medulloblastoma Recurrent

2 locations incl. Houston

Sponsor: Mohammad H. Abu Arja

Sex: All·Age: 3 - 50

Code: NCT07242963·Recruiting

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T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

for Metastatic Soft-tissue Sarcoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 12+

Code: NCT06474676·Phase 1·Recruiting

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A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)

for T-cell Acute Lymphoblastic Leukemia

Drug: Venetoclax

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 1 Month - 21

Code: NCT06561074·Phase 2·Recruiting

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Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma

for Clear Cell Carcinoma

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07072234·Phase 1·Recruiting

Apply to this trial