Solid tumor Clinical Trials in Houston, TX

As of June 2026, 206 paid clinical trials are recruiting for Solid tumor in Houston, Texas. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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206 clinical trials for Solid tumor

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for Solid Tumors

7 locations incl. Denver

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06386146·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

17 locations incl. Irvine

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting

Apply to this trial

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

17 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting

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A Study of BGC515 Capsules in Subjects With Advanced Solid Tumors

for Mesothelioma

1 location in Houston

Sponsor: BridGene Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06452160·Phase 1·Recruiting

Apply to this trial

Study of APR-1051 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

3 locations incl. Houston

Sponsor: Aprea Therapeutics

Sex: All·Age: 18+

Code: NCT06260514·Phase 1·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor, Adult

10 locations incl. Denver

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06507306·Phase 1·Recruiting

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Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for Malignant Female Reproductive System Neoplasm

186 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06126276·Phase 2·Recruiting

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Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

for Advanced Solid Tumor

6 locations incl. Scottsdale

Sponsor: Strand Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06249048·Phase 1, Phase 2·Recruiting

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A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer

for Advanced Solid Tumor

1 location in Houston

Sponsor: SOTIO Biotech AG

Sex: All·Age: 18+

Code: NCT06163391·Phase 1·Recruiting

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A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

11 locations incl. Aurora

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06384352·Phase 1·Recruiting

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A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

17 locations incl. San Francisco

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting

Apply to this trial

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

16 locations incl. Fountain Valley

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05932862·Phase 1·Recruiting

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

18 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting

Apply to this trial

A Study of MGC026 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

7 locations incl. Los Angeles

Sponsor: MacroGenics

Sex: All·Age: 18+

Code: NCT06242470·Phase 1·Recruiting

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A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

13 locations incl. Duarte

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06172478·Phase 2·Recruiting

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SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. New Haven

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting

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A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

for Advanced Solid Tumor

20 locations incl. Irvine

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06244485·Phase 1·Recruiting

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

15 locations incl. La Jolla

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting

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A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Denver

Sponsor: OnCusp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06234423·Phase 1·Recruiting

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QTX3034 in Patients With KRAS G12D Mutation

for Solid Tumors

14 locations incl. Los Angeles

Sponsor: Quanta Therapeutics

Sex: All·Age: 18+

Code: NCT06227377·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

9 locations incl. Duarte

Sponsor: Vividion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06004245·Phase 1·Recruiting

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Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

4 locations incl. Boston

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06167317·Phase 1·Recruiting

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FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

for Advanced Solid Tumor

14 locations incl. Gilbert

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT06241456·Phase 1·Recruiting

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A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

for Solid Tumors

Drug: INCB161734

16 locations incl. Phoenix

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06179160·Phase 1·Recruiting

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CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

5 locations incl. Los Angeles

Sponsor: Cullinan Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06035744·Phase 1·Recruiting

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A Study of ATG-031 in Advanced Solid Tumors or B-cell Non-Hodgkin Lymphomas

for Advanced Solid Tumors

4 locations incl. San Francisco

Sponsor: Antengene Biologics Limited

Sex: All·Age: 18+

Code: NCT06028373·Phase 1·Recruiting

Apply to this trial

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

for Advanced Solid Tumor

10 locations incl. Denver

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06120283·Phase 1·Recruiting

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Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations

for Locally Advanced Cholangiocarcinoma

4 locations incl. San Francisco

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06160752·Phase 1·Recruiting

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JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

10 locations incl. Encinitas

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06108050·Phase 1·Recruiting

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Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

for Solid Tumor

4 locations incl. Scottsdale

Sponsor: Qualigen Theraputics, Inc.

Sex: All·Age: 18+

Code: NCT06086522·Phase 1·Recruiting

Apply to this trial

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for Advanced Solid Tumor

Drug: NXP900

10 locations incl. Phoenix

Sponsor: Nuvectis Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05873686·Phase 1·Recruiting

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Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

for Solid Tumors

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06066424·Phase 1·Recruiting

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Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

for Advanced Solid Tumors

3 locations incl. Cincinnati

Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All·Age: 18+

Code: NCT06096974·Phase 1·Recruiting

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A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

14 locations incl. Los Angeles

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting

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A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

for Advanced Solid Tumors

7 locations incl. Los Angeles

Sponsor: LigaChem Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05941507·Phase 1, Phase 2·Recruiting

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A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

9 locations incl. Duarte

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05981703·Phase 1·Recruiting

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Study to Evaluate IMGS-001 Treatment in Patients With Relapsed or Refractory Advanced Solid Tumors

for Solid Tumor

6 locations incl. Gilbert

Sponsor: ImmunoGenesis

Sex: All·Age: 18+

Code: NCT06014502·Phase 1·Recruiting

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Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

for Non-small Cell Lung Cancer (NSCLC)

17 locations incl. Sacramento

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06040541·Phase 1·Recruiting

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First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

6 locations incl. Sarasota

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT05875168·Phase 1, Phase 2·Recruiting

Apply to this trial