Paid Clinical Trials in Hershey, PA

As of June 2026, 293 paid clinical trials are recruiting in Hershey, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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292 clinical trials

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Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

for Systemic Lupus Erythematosus

10 locations incl. Los Angeles

Sponsor: NYU Langone Health

Sex: All·Age: 60+

Code: NCT05799378·Phase 3·Recruiting

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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Medical Residents Learning Weight Management Counseling Skills

for Weight Management Counseling

8 locations incl. Palo Alto

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06529666·Recruiting

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

53 locations incl. Anchorage

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting

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Evaluation of a Monofocal Intraocular Lens

for Cataract

3 locations incl. Indianapolis

Sponsor: Carl Zeiss Meditec AG

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06428955·Phase 4·Recruiting

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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for Crohn's Disease

Drug: Tulisokibart

87 locations incl. Dothan

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16 - 80

Code: NCT06430801·Phase 3·Recruiting

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Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

for Metastatic Breast Cancer

29 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06324357·Phase 1, Phase 2·Recruiting

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Feasibility of a Mindfulness Intervention for Endometriosis Surgery

for Endometriosis

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: Female·Age: 18+

Code: NCT06141720·Recruiting

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A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

for Healthy Participants

9 locations incl. Glendale

Sponsor: Equilibra Bioscience LLC

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06349473·Phase 1·Recruiting

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Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

for Osteoarthritis of Shoulder

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 45+

Code: NCT03921944·Recruiting

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NICU Antibiotics and Outcomes (NANO) Follow-up Study

for Premature Birth

14 locations incl. San Diego

Sponsor: Sharp HealthCare

Sex: All·Age: 23 Weeks - 30 Weeks

Code: NCT05977400·Phase 3·Not Yet Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

Apply to this trial

iLookOut for Child Abuse: Micro-learning to Improve Knowledge Retention

for Child Abuse

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT04324619·Recruiting

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iLookOut Micro-learning to Improve Knowledge Retention

for Knowledge

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06273618·Recruiting

Apply to this trial

Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

10 locations incl. Los Angeles

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting

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A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for Non Small Cell Lung Cancer

49 locations incl. Little Rock

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312137·Phase 3·Recruiting

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The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

for Polycystic Ovary Syndrome

24 locations incl. Encino

Sponsor: May Health

Sex: Female·Age: 18 - 40

Code: NCT06206746·Recruiting

Apply to this trial

Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

for Physical Inactivity

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT05826379·Enrolling By Invitation

Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

for Insomnia

3 locations incl. Denver

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06281756·EARLY_Phase 1·Recruiting

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Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

for Attention-Deficit/Hyperactivity Disorder

47 locations incl. Saraland

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 48 Months - 69 Months

Code: NCT04781140·Phase 4·Recruiting

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Maintenance Obinutuzumab in Treating Patients With Central Nervous System Lymphoma Who Have Achieved a Complete or Partial Response

for Primary Central Nervous System Lymphoma

7 locations incl. New York

Sponsor: Providence Health & Services

Sex: All·Age: 18+

Code: NCT06175000·Phase 2·Recruiting

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

20 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting

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Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

for Breast Cancer

673 locations incl. Anchorage

Sponsor: NRG Oncology

Sex: All·Age: 18 - 100

Code: NCT05896189·Recruiting

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An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy

for Duchenne Muscular Dystrophy

25 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: 4+

Code: NCT06270719·Enrolling By Invitation

Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

for Rhinoplasty

1 location in Hershey

Sponsor: Jessyka Lighthall

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05964868·Phase 3·Enrolling By Invitation

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

for Glioblastoma

19 locations incl. Phoenix

Sponsor: CarThera

Sex: All·Age: 18+

Code: NCT05902169·Phase 3·Recruiting

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A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

for Multiple Myeloma

Drug: Talquetamab

49 locations incl. Clovis

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06208150·Phase 3·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy

for Colorectal Surgery

3 locations incl. Buffalo

Sponsor: JSR Medical Co., Ltd.

Sex: All·Age: 19 - 80·Accepts healthy volunteers

Code: NCT05826743·Recruiting

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A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

205 locations incl. Birmingham

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

51 locations incl. Birmingham

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting

Apply to this trial

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

47 locations incl. Phoenix

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting

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Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

for Spinal Muscular Atrophy

15 locations incl. Phoenix

Sponsor: Alcyone Therapeutics, Inc

Sex: All·Age: 3+

Code: NCT05866419·Recruiting

Apply to this trial

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis

for Sinus Infection

7 locations incl. Los Angeles

Sponsor: Daniel Merenstein

Sex: All·Age: 18 - 75

Code: NCT06076304·Phase 4·Recruiting

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Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)

for Ileal Pouch

8 locations incl. Los Angeles

Sponsor: Exegi Pharma, LLC

Sex: All·Age: 18+

Code: NCT05938465·Phase 1, Phase 2·Recruiting

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TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

17 locations incl. Phoenix

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting

Apply to this trial

Open vs. Blind Weighing Study In Adolescents and Young Adult With Eating Disorders

for Eating Disorders

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 12 - 24

Code: NCT06085092·Recruiting

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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

71 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting

Apply to this trial