Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinomafor Endometrial AdenocarcinomaDrug: Ipilimumab137 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: Female·Age: 18+Code: NCT05112601·Phase 2·RecruitingApply to this trial
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Programfor Cigarette Smoking-Related Carcinoma222 locations incl. KingmanSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT05008848·Phase 3·RecruitingApply to this trial
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcomafor Metastatic Malignant Neoplasm in the Lung219 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: Up to 50Code: NCT05235165·Phase 3·RecruitingApply to this trial
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polypsfor Adenocarcinoma of the Colon472 locations incl. FairbanksSponsor: NRG OncologySex: All·Age: 45 - 70Code: NCT05080673·RecruitingApply to this trial
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumorsfor Malignant Solid Neoplasm843 locations incl. AnchorageSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT04871542·RecruitingApply to this trial
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTfor Central Nervous System Nongerminomatous Germ Cell Tumor149 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: 3 - 29Code: NCT04684368·Phase 2·RecruitingApply to this trial
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)for Stage I Breast Cancer812 locations incl. BirminghamSponsor: NRG OncologySex: All·Age: 50 - 70Code: NCT04852887·Phase 3·RecruitingApply to this trial
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Studyfor Chronic Lymphocytic Leukemia621 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT04269902·Phase 3·RecruitingApply to this trial
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trialfor Plasma Cell Myeloma642 locations incl. AnchorageSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT04566328·Phase 3·RecruitingApply to this trial
Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)for Recurrent T Acute Lymphoblastic Leukemia163 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 12+Code: NCT04315324·Phase 1, Phase 2·RecruitingApply to this trial
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)for Down SyndromeDrug: Nivolumab202 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 1 - 30Code: NCT04546399·Phase 2·RecruitingApply to this trial
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancerfor Ovarian Carcinoma539 locations incl. BirminghamSponsor: NRG OncologySex: Female·Age: 35 - 50Code: NCT04251052·RecruitingApply to this trial
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkersfor Pancreatic Neoplasm408 locations incl. BirminghamSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 50 - 75Code: NCT04239573·RecruitingApply to this trial
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])for Lung Non-Small Cell Carcinoma1150 locations incl. AnchorageSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT04267848·Phase 3·RecruitingApply to this trial
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancersfor Metastatic Small Intestinal Adenocarcinoma536 locations incl. AnchorageSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT04205968·Phase 2·RecruitingApply to this trial
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myelomafor Smoldering Plasma Cell MyelomaDrug: Daratumumab741 locations incl. BirminghamSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT03937635·Phase 3·RecruitingApply to this trial
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancerfor Previously Treated Non-Small Cell Lung Cancer1229 locations incl. BirminghamSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT03851445·Phase 2, Phase 3·RecruitingApply to this trial
Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancerfor Breast Cancer451 locations incl. FairbanksSponsor: Canadian Cancer Trials GroupSex: Female·Age: 35+Code: NCT03488693·Phase 3·RecruitingApply to this trial
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Changefor Advanced Lung Non-Small Cell CarcinomaDrug: Osimertinib345 locations incl. AnchorageSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT03191149·Phase 2·RecruitingApply to this trial
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemiafor B Acute Lymphoblastic Leukemia455 locations incl. BirminghamSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18 - 39Code: NCT03150693·Phase 3·RecruitingApply to this trial
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumorsfor Childhood Extracranial Germ Cell Tumor566 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: All agesCode: NCT03067181·Phase 3·RecruitingApply to this trial
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgeryfor Head and Neck Squamous Cell Carcinoma676 locations incl. BirminghamSponsor: ECOG-ACRIN Cancer Research GroupSex: All·Age: 18+Code: NCT02734537·Phase 2·RecruitingApply to this trial
Project: Every Child for Younger Patients With Cancerfor Adrenal Gland Pheochromocytoma245 locations incl. BirminghamSponsor: Children's Oncology GroupSex: All·Age: Up to 25Code: NCT02402244·RecruitingApply to this trial
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomasfor Intracranial Meningioma780 locations incl. BirminghamSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT02523014·Phase 2·RecruitingApply to this trial
Collection and Storage of Tissue and Blood Samples From Patients With Cancerfor Hematopoietic and Lymphatic System Neoplasm140 locations incl. BirminghamSponsor: National Cancer Institute LAOSex: All·Age: 2 Months+Code: NCT02474160·RecruitingApply to this trial
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancerfor Oropharyngeal p16INK4a-Negative Squamous Cell CarcinomaDrug: Atezolizumab338 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT01810913·Phase 2, Phase 3·RecruitingApply to this trial