Clinical Trials at Duke University Hospital

As of June 2026, 58 paid clinical trials are recruiting at Duke University Hospital, located at 908A ONSLOW ST, DURHAM, NC 27705-4247, phone (203) 376-4428 in Durham, North Carolina. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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58 clinical trials at Duke University Hospital

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Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

for Cardiac Resynchronization Therapy

4 locations incl. Chicago

Sponsor: XSpline S.p.A.

Sex: All·Age: 18+

Code: NCT05327062·Recruiting

Apply to this trial

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

for Multiple Myeloma

13 locations incl. San Francisco

Sponsor: K36 Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05651932·Phase 1·Recruiting

Apply to this trial

Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

for Colorectal Neoplasms

128 locations incl. Glendale

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05253651·Phase 3·Recruiting

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

45 locations incl. Birmingham

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05338697·Recruiting

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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

35 locations incl. Birmingham

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting

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REMASTer: REcurrent Brain Metastases After SRS Trial

for Brain Metastases

9 locations incl. Los Angeles

Sponsor: Monteris Medical

Sex: All·Age: 18+

Code: NCT05124912·Recruiting

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

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Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

for Mitral Valve Regurgitation

24 locations incl. Los Angeles

Sponsor: Annetine Gelijns

Sex: All·Age: 60+

Code: NCT05051033·Recruiting

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Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

for Shoulder Surgery

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18 - 80

Code: NCT04209504·Recruiting

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Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

for Tourniquet Hypertension

1 location in Durham

Sponsor: Duke University

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT04454203·Phase 4·Recruiting

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Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

for Mitral Regurgitation

2 locations incl. Durham

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT04761120·Recruiting

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The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

10 locations incl. San Diego

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting

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Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

for Intraabdominal Hypertension

9 locations incl. Los Angeles

Sponsor: Potrero Medical

Sex: All·Age: 18+

Code: NCT04669548·Recruiting

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TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

for BRCA1 Gene Mutation

11 locations incl. Chicago

Sponsor: University Medical Center Nijmegen

Sex: Female·Age: 25 - 50

Code: NCT04294927·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Hyperbaric Oxygen Brain Injury Treatment Trial

for Traumatic Brain Injury

10 locations incl. San Diego

Sponsor: Gaylan Rockswold

Sex: All·Age: 16 - 65

Code: NCT02407028·Phase 2·Recruiting

Apply to this trial