Clinical Trials at City of Hope

As of June 2026, 145 paid clinical trials are recruiting at City of Hope, located at 1500 DUARTE RD, DUARTE, CA 91010-3012, phone (626) 256-4673 in Duarte, California. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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145 clinical trials at City of Hope

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A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

for Advanced Liver Cancers

16 locations incl. Costa Mesa

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04524871·Phase 1, Phase 2·Recruiting

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

45 locations incl. Phoenix

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting

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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for Prostate Carcinoma

8 locations incl. Duarte

Sponsor: University of Washington

Sex: Male·Age: 40+·Accepts healthy volunteers

Code: NCT04472338·Recruiting

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Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

for CLL/SLL

7 locations incl. Duarte

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18 - 85

Code: NCT04215809·Phase 1·Recruiting

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Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

for Leukemia, Myeloid, Chronic

8 locations incl. Birmingham

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT04260022·Phase 1·Recruiting

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KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)

for Carcinoma, Non-Small-Cell Lung

18 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT04165070·Phase 1, Phase 2·Recruiting

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KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

for Carcinoma, Non-Small-Cell Lung

18 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT04165798·Recruiting

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

32 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting

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Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer

for Metastatic Breast Cancer

11 locations incl. Gilbert

Sponsor: Phoenix Molecular Designs

Sex: All·Age: 18+

Code: NCT04115306·Phase 1, Phase 2·Recruiting

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A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

for Acute Myeloid Leukemia

11 locations incl. Duarte

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 12 - 78

Code: NCT03802695·Phase 1·Recruiting

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Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

for Non-Hodgkin Lymphoma

18 locations incl. Gilbert

Sponsor: Imugene Limited

Sex: All·Age: 18+

Code: NCT03666000·Phase 1·Recruiting

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Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma

for Bone Pain

9 locations incl. Duarte

Sponsor: University of Southern California

Sex: All·Age: 18+

Code: NCT03858205·Recruiting

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Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

23 locations incl. Scottsdale

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting

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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

for B-cell Acute Lymphoblastic Leukemia

24 locations incl. Birmingham

Sponsor: Pediatric Transplantation & Cellular Therapy Consortium

Sex: All·Age: 1 - 25

Code: NCT03509961·Phase 2·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for Metastatic Breast Cancer

16 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT03424005·Phase 1, Phase 2·Recruiting

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CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for Relapsed Hematologic Malignancy

Drug: Emavusertib

27 locations incl. Phoenix

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT03328078·Phase 1, Phase 2·Recruiting

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Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

for Leukemia, Lymphocytic, Chronic, B-Cell

84 locations incl. Birmingham

Sponsor: Juno Therapeutics, a Subsidiary of Celgene

Sex: All·Age: 18+

Code: NCT03331198·Phase 1, Phase 2·Recruiting

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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for Acute Myeloid Leukemia

Drug: Venetoclax

3 locations incl. Duarte

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03113643·Phase 1·Recruiting

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ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome

for Mycosis Fungoides

7 locations incl. Duarte

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT02848274·Recruiting

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MEASuRE: Metreleptin Effectiveness And Safety Registry

for Generalised Lipodystrophy

16 locations incl. Birmingham

Sponsor: Amryt Pharma

Sex: All·Age: All ages

Code: NCT02325674·Recruiting

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Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

26 locations incl. Birmingham

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

71 locations incl. Birmingham

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

42 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting

Apply to this trial