Oncology Clinical Trials in Duarte, CA

As of June 2026, 306 paid clinical trials are recruiting for Oncology in Duarte, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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306 clinical trials for Oncology

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Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

for Ovarian Cancer

13 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05797168·Phase 1, Phase 2·Recruiting

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

9 locations incl. Duarte

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting

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Phase II Trial of Lung Chemoemobolization

for Lung Non-Small Cell Carcinoma

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672108·Phase 2·Recruiting

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Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05733949·Recruiting

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Early Onset Colorectal Cancer Detection

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06342401·Recruiting

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Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for Prostate Cancer

5 locations incl. Duarte

Sponsor: Varian, a Siemens Healthineers Company

Sex: Male·Age: 18+

Code: NCT05804318·Recruiting

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Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

Drug: Lifileucel

22 locations incl. Birmingham

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting

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Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

for Gastric or Gastroesophageal Junction Adenocarcinoma

11 locations incl. Duarte

Sponsor: Phanes Therapeutics

Sex: All·Age: 18+

Code: NCT05482893·Phase 1, Phase 2·Recruiting

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

9 locations incl. Phoenix

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting

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Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

for Lymphoblastic Leukemia

3 locations incl. Duarte

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 30

Code: NCT05194397·Phase 2·Recruiting

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Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study

for Hematopoietic and Lymphoid System Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05772130·Recruiting

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

313 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting

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Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

for Breast Cancer

45 locations incl. Dothan

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05563220·Phase 1, Phase 2·Recruiting

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Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

for Non-Hodgkin Lymphoma, Adult

7 locations incl. Duarte

Sponsor: Marker Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05798897·Phase 1·Recruiting

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An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05376878·Phase 4·Recruiting

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Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers

for Bladder Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05519878·Recruiting

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GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

for SCLC

8 locations incl. Scottsdale

Sponsor: Y-mAbs Therapeutics

Sex: All·Age: 16+

Code: NCT05130255·Phase 1·Recruiting

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Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for Advanced Malignant Solid Neoplasm

36 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05327010·Phase 2·Recruiting

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Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for Recurrent B-Cell Non-Hodgkin Lymphoma

Drug: Nivolumab

9 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05272384·Phase 1·Recruiting

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A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation

for AML

15 locations incl. Duarte

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05473910·Phase 1·Recruiting

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A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

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Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for Platinum-resistant Ovarian Cancer

Drug: Bevacizumab

31 locations incl. Mobile

Sponsor: Genelux Corporation

Sex: Female·Age: 18+

Code: NCT05281471·Phase 3·Recruiting

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AOH1996 for the Treatment of Refractory Solid Tumors

for Refractory Malignant Solid Neoplasm

2 locations incl. Scottsdale

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05227326·Phase 1·Recruiting

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A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

for Lymphoma, Non-Hodgkin

14 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05421663·Phase 1, Phase 2·Recruiting

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

51 locations incl. Mobile

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting

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LYL273 for Patients With Relapsed or Refractory mCRC

for Colorectal Cancer

4 locations incl. Duarte

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05319314·Phase 1, Phase 2·Recruiting

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Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer

for Lung Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05384769·Recruiting

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Study of INCB123667 in Subjects With Advanced Solid Tumors

for Solid Tumors

Drug: INCB123667

19 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05238922·Phase 1·Recruiting

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Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

for End of Life

17 locations incl. Birmingham

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT05297734·Recruiting

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Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma

for Marginal Zone Lymphoma

4 locations incl. Duarte

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT05296070·Phase 2·Recruiting

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Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)

for Metastatic Malignant Solid Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05371132·Phase 1·Recruiting

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A Study of ASP3082 in Adults With Advanced Solid Tumors

for Solid Tumor

23 locations incl. Duarte

Sponsor: Astellas Pharma Inc

Sex: All·Age: 18+

Code: NCT05382559·Phase 1·Recruiting

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Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

for Myelofibrosis

22 locations incl. Duarte

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT05320198·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

for Myelofibrosis

Drug: Ruxolitinib

8 locations incl. Duarte

Sponsor: Geron Corporation

Sex: All·Age: 18+

Code: NCT05371964·Phase 1·Recruiting

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A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2

for Urothelial Carcinoma

159 locations incl. Gilbert

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04879329·Phase 2·Recruiting

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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

17 locations incl. Duarte

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting

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Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for Cancer

5 locations incl. Duarte

Sponsor: RefleXion Medical

Sex: All·Age: All ages

Code: NCT05406167·Recruiting

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A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

Drug: Telisotuzumab Vedotin

50 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT04928846·Phase 3·Recruiting

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Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

for GEP-NET

32 locations incl. Phoenix

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT05477576·Phase 3·Recruiting

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

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Conditions in Oncology (Duarte, CA)

Solid tumor· 48 Non-small cell lung cancer (NSCLC)· 35 Acute myeloid leukemia (AML)· 32 Myelodysplastic syndromes (MDS)· 28 Breast cancer· 26 Hematologic malignancy· 25 Colorectal cancer· 21 Prostate cancer· 20 Pancreatic cancer· 18 Ovarian cancer· 18 Non-Hodgkin lymphoma· 16 Metastatic breast cancer· 15 Cancer (any)· 15 Gastric cancer· 14 Esophageal cancer· 14 Multiple myeloma· 14 Endometrial cancer· 12 Acute lymphoblastic leukemia· 12 Head and neck cancer· 12 Leukemia (other)· 11 Diffuse large B-cell lymphoma (DLBCL)· 11 Bladder cancer· 9 Chronic lymphocytic leukemia (CLL)· 9 Mantle cell lymphoma· 9 Kidney cancer· 8 Myelofibrosis· 8 Lung cancer· 7 Gastroesophageal junction cancer· 7 Biliary tract cancer· 7 Cervical cancer· 7 Hodgkin lymphoma· 7 Small lymphocytic lymphoma· 7 Melanoma· 7 Triple-negative breast cancer· 6 Liver cancer· 5 Myeloproliferative neoplasm· 5 Follicular lymphoma· 5 Sarcoma· 5 Metastatic prostate cancer· 4 Marginal zone lymphoma· 4 Neuroendocrine tumors· 4 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Chronic myelomonocytic leukemia· 3 Small cell lung cancer· 2 Glioblastoma· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Neuroblastoma· 1 Mesothelioma· 1