Clinical Trials at University of Texas Southwestern Medical Center

As of June 2026, 205 paid clinical trials are recruiting at University of Texas Southwestern Medical Center, located at 5323 HARRY HINES BLVD, DALLAS, TX 75390, phone (214) 648-7833 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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205 clinical trials at University of Texas Southwestern Medical Center

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Periprostatic Neurolysis in Prostate Cancer

for PROSTATE CANCER

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 18+

Code: NCT07100847·Phase 1·Recruiting

Apply to this trial

A Long-Term Study of JNT-517 in Participants With Phenylketonuria

for Phenylketonuria (PKU)

8 locations incl. Gainesville

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 4+

Code: NCT06628128·Phase 3·Recruiting

Apply to this trial

A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections

for Recurrent UTIs

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 55 - 85

Code: NCT06940622·Recruiting

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Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for Atherosclerotic Cardiovascular Disease

139 locations incl. Daphne

Sponsor: Amgen

Sex: All·Age: 45 - 99

Code: NCT07037433·Phase 3·Recruiting

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

Drug: Empagliflozin

216 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting

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XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)

for Heart Transplant

14 locations incl. La Jolla

Sponsor: XVIVO Perfusion

Sex: All·Age: 18+

Code: NCT06895070·Recruiting

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Radiation Free Study

for Aortic Aneurysm

4 locations incl. Birmingham

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06549348·Recruiting

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Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

for Small Bowel Adenocarcinoma

6 locations incl. Tampa

Sponsor: Tiago Biachi de Castria

Sex: All·Age: 18+

Code: NCT06835387·Phase 2·Recruiting

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A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

for Heart Failure

29 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 40 - 84

Code: NCT06979362·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

Apply to this trial

Phosphate Assessment in Chronic Kidney Disease Patients Study

for Chronic Kidney Disease (Stage 3-4)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07368946·Recruiting

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Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

6 locations incl. Scottsdale

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting

Apply to this trial

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting

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Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

for Neuroblastoma

6 locations incl. Hartford

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06831552·Recruiting

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IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

for Non Hodgkin Lymphoma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06768905·Phase 1, Phase 2·Recruiting

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A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

for Multiple Sclerosis

8 locations incl. Boston

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18 - 55

Code: NCT06735248·Phase 2·Recruiting

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PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma

6 locations incl. Newport Beach

Sponsor: PanTher Therapeutics

Sex: All·Age: 18+

Code: NCT06673017·Phase 1·Recruiting

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Radiotherapy in Combination With Checkpoint Inhibition for Patients With Metastatic Kidney Cancer

for Metastatic Renal Cell Carcinoma ( mRCC)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06601296·Phase 2·Recruiting

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A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for HR+ Breast Cancer

14 locations incl. La Jolla

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07029399·Phase 1·Recruiting

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A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma, Clear Cell

Drug: Ipilimumab

6 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06708949·Phase 2·Recruiting

Apply to this trial

DETECT-RPC Universal EM Screening

for Elder Abuse

7 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT05958654·Recruiting

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Ligufalimab and Cadonilimab in Advanced Liver Cancers

for Advanced Hepatocellular Carcinoma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06789848·Phase 2·Recruiting

Apply to this trial

Tailored Exercise Training Study Among Adults With HFpEF

for HFpEF - Heart Failure With Preserved Ejection Fraction

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07223242·Phase 2, Phase 3·Recruiting

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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

for Neurofibromatosis Type 1

14 locations incl. Birmingham

Sponsor: Healx Limited

Sex: All·Age: 12+

Code: NCT06541847·Phase 2·Recruiting

Apply to this trial

NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study

for Type 2 Diabetes

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages

Code: NCT06593327·Recruiting

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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for mCRPC (Metastatic Castration-resistant Prostate Cancer)

18 locations incl. Fountain Valley

Sponsor: Pathos AI, Inc.

Sex: Male·Age: 18+

Code: NCT06785636·Phase 1, Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer

for Prostate Cancer

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18+

Code: NCT05726292·Phase 2·Recruiting

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Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM

for Waldenstrom Macroglobulinemia

Drug: Rituximab

5 locations incl. Denver

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06561347·Phase 2·Recruiting

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The Effect of Adiposity on Muscle and Microvascular Function in HFpEF

for Heart Failure With Preserved Ejection Fraction (HFPEF)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06930495·Enrolling By Invitation

Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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Training for Urinary Leakage Improvement After Pregnancy

for Urinary Incontinence

7 locations incl. San Diego

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18+

Code: NCT06411158·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

152 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

29 locations incl. St. Helena

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting

Apply to this trial

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

for Solid Tumor, Adult

19 locations incl. Duarte

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06625775·Phase 1·Recruiting

Apply to this trial

A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer

for Advanced Breast Cancer

35 locations incl. Springdale

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06638307·Phase 1·Recruiting

Apply to this trial

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

for Inguinal Hernia

3 locations incl. Dallas

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT04706026·Recruiting

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A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

35 locations incl. California City

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting

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APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML

for Acute Myeloid Leukemia (AML)

7 locations incl. Denver

Sponsor: Aptevo Therapeutics

Sex: All·Age: 18+

Code: NCT06634394·Phase 1·Recruiting

Apply to this trial