Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
for Type 2 Diabetes Mellitus
79 locations incl. Huntsville
Sponsor: Prokidney
Sex: All·Age: 30 - 80
Code: NCT05099770·Phase 3·Recruiting
Nephrology Clinical Trials in Dakota Dunes, SD
As of June 2026, 1 paid clinical trial is recruiting for Nephrology in Dakota Dunes, South Dakota. Nephrology trials evaluate SGLT-2 inhibitors, MR antagonists, novel anemia treatments, and dialysis innovations across chronic kidney disease, end-stage renal disease, and acute kidney injury. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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1 clinical trial for Nephrology
·Clear filters·↓ Download CSVAbout research studies in Dakota Dunes
Dakota Dunes has approximately 8 recruiting research studies across a wide range of therapeutic areas. South Dakota hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Dakota Dunes
Researchers run research studies in Dakota Dunes, SD at 5 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Dunes Clinical Research | Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2 | 3 |
| ADARx Clinical Site | C3G, Complement-mediated Kidney Disease, IC-MPGN | 1 |
| Clinical Research | Immunoglobulin A Nephropathy | 1 |
| Clinical Research | IgA Nephropathy | 1 |
| Dunes Eye Consultants | MGD-Meibomian Gland Dysfunction | 1 |
Active & Upcoming Studies in Dakota Dunes (2026)
Recruiting trials in Dakota Dunes grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Diabetes & metabolic (2 active studies)
- EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease · Phase 3 · Boehringer Ingelheim
- Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease · Phase 3 · Prokidney
Cardiovascular (1 active study)
Common conditions studied in Dakota Dunes
- IgA Nephropathy (2 active studies). Recruiting IgA Nephropathy studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- C3G (1 active study). Recruiting C3G studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cardiovascular Diseases (1 active study). Recruiting Cardiovascular Diseases studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Chronic Kidney Diseases (1 active study). Kidney disease trials investigate SGLT-2 inhibitors, mineralocorticoid receptor antagonists, and novel antifibrotic therapies to slow progression.
- Complement-mediated Kidney Disease (1 active study). Kidney disease trials investigate SGLT-2 inhibitors, mineralocorticoid receptor antagonists, and novel antifibrotic therapies to slow progression.
- Diabetes Mellitus, Type 2 (1 active study). Diabetes trials evaluate new insulin formulations, GLP-1 receptor agonists, continuous glucose monitoring technologies, and disease-modifying therapies.
Leading research sponsors in Dakota Dunes
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- ADARx Pharmaceuticals, Inc.
- Biohaven Therapeutics Ltd.
- Boehringer Ingelheim
- Dunes Eye Consultants
Local regulations and guidelines
Clinical trials in South Dakota are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Dakota research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Dakota Dunes. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Dakota Dunes
Hipa.ai aggregates every recruiting study in Dakota Dunes from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Dakota Dunes?
There are approximately 8 recruiting clinical trials in Dakota Dunes, South Dakota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dakota Dunes pay participants?
Most recruiting trials in Dakota Dunes compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dakota Dunes?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dakota Dunes?
The most common conditions under active study in Dakota Dunes include IgA Nephropathy (2), C3G (1), Cardiovascular Diseases (1), Chronic Kidney Diseases (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dakota Dunes?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dakota Dunes on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dakota Dunes?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dakota Dunes?
Recruiting research sites in Dakota Dunes include Dunes Clinical Research, ADARx Clinical Site, Clinical Research, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dakota Dunes right now?
The largest active categories in Dakota Dunes are Diabetes & metabolic (2), Cardiovascular (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.