Clinical Trials at University Hospitals Cleveland Medical Center

As of June 2026, 165 paid clinical trials are recruiting at University Hospitals Cleveland Medical Center, located at 11100 EUCLID AVE, CLEVELAND, OH 44106-1716, phone (216) 844-8447 in Cleveland, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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165 clinical trials at University Hospitals Cleveland Medical Center

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A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

for Prostatic Neoplasms

4 locations incl. Sarasota

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07082920·Phase 1·Recruiting

Apply to this trial

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting

Apply to this trial

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

15 locations incl. Huntsville

Sponsor: Biogen

Sex: All·Age: 18 - 80

Code: NCT06962800·Phase 3·Recruiting

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

18 locations incl. Phoenix

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting

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BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

for Stress Urinary Incontinence

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18+

Code: NCT06754046·Recruiting

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Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for Peripheral Arterial Diseases

9 locations incl. Phoenix

Sponsor: Angiodynamics, Inc.

Sex: All·Age: All ages

Code: NCT06777901·Phase 4·Recruiting

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Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

for Peripheral Arterial Disease

3 locations incl. Beachwood

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 99

Code: NCT06544135·Recruiting

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L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

for Acute Myeloid Leukaemia (AML)

6 locations incl. Miami

Sponsor: Moleculin Biotech, Inc.

Sex: All·Age: 18 - 80

Code: NCT06788756·Phase 2, Phase 3·Recruiting

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Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for Barrett Esophagus

5 locations incl. Aurora

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06687603·Recruiting

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Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for Non Small Cell Lung Carcinoma

26 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06772623·Phase 1, Phase 2·Recruiting

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Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

Apply to this trial

Postpartum Vaginal Estrogen for Breastfeeding Patients

for Breastfeeding

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18 - 50

Code: NCT05457972·Phase 4·Recruiting

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Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

for Glomerulonephritis, IGA

Drug: Iptacopan

9 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT06797518·Phase 2·Recruiting

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A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

for Parkinson Disease

27 locations incl. Phoenix

Sponsor: Impax Laboratories, LLC

Sex: All·Age: 18+

Code: NCT06765668·Phase 4·Recruiting

Apply to this trial

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

for Rotator Cuff Tears

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06733480·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

for Extensive-stage Small-cell Lung Cancer

32 locations incl. Tucson

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06712355·Phase 3·Recruiting

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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

66 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

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A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

for Ulcerative Colitis

14 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06100289·Phase 3·Recruiting

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Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

for Arterial Disease of Legs

29 locations incl. Scottsdale

Sponsor: Concept Medical Inc.

Sex: All·Age: 21+

Code: NCT06182397·Recruiting

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Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

for Malignant Mesothelioma

6 locations incl. Denver

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06566079·Phase 1·Recruiting

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Milk Thistle Clinical Trial in Pediatric NAFLD

for Non-Alcoholic Fatty Liver Disease (NAFLD)

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 9 - 22

Code: NCT06477146·Phase 2·Recruiting

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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

for Heart Failure

88 locations incl. Alexander City

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT06736574·Phase 3·Recruiting

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Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

for Clinical Stage IA Cutaneous Melanoma AJCC v8

5 locations incl. Davis

Sponsor: OHSU Knight Cancer Institute

Sex: All·Age: 18+

Code: NCT06673095·Recruiting

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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Upadacitinib

3 locations incl. Cleveland

Sponsor: CARE ARTHRITIS LTD.

Sex: All·Age: 18+

Code: NCT06454188·Phase 4·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

152 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

18 locations incl. Phoenix

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

Apply to this trial

AltaValve Pivotal Trial

for Mitral Regurgitation

20 locations incl. Phoenix

Sponsor: 4C Medical Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06465745·Recruiting

Apply to this trial

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

for Kidney Disease, Chronic

Drug: Empagliflozin

41 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06531824·Phase 3·Recruiting

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A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

for Multiple Myeloma

9 locations incl. San Francisco

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06500884·Phase 2·Recruiting

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A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

29 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting

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SW-682 in Advanced Solid Tumors

for Advanced Solid Tumor

8 locations incl. Scottsdale

Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06251310·Phase 1·Recruiting

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A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

for Hepatocellular Carcinoma

Drug: Atezolizumab

60 locations incl. Tucson

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06096779·Phase 2·Recruiting

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A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Drug: riliprubart

27 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290128·Phase 3·Recruiting

Apply to this trial