Clinical Trials at Northwestern University

As of June 2026, 381 paid clinical trials are recruiting at Northwestern University, located at 303 E CHICAGO AVE, TARRY BUILDING, 11-703, CHICAGO, IL 60611-3008, phone (312) 503-0830 in Chicago, Illinois. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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381 clinical trials at Northwestern University

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Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

for Glioblastoma

19 locations incl. Phoenix

Sponsor: CarThera

Sex: All·Age: 18+

Code: NCT05902169·Phase 3·Recruiting

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A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

for Phenylketonuria (PKU)

11 locations incl. Aurora

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT06305234·Recruiting

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Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

for Newly Diagnosed Glioblastoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05864534·Phase 2·Recruiting

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Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease

for Chronic Kidney Diseases

Drug: Dapagliflozin

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT05719714·Phase 1, Phase 2·Recruiting

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Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

for Metastatic Digestive System Neuroendocrine Tumor G1

33 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05773274·Phase 2·Recruiting

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5-SENSE Score Validation Study

for Epilepsy Intractable

4 locations incl. Gainesville

Sponsor: Duke University

Sex: All·Age: 15+

Code: NCT06138808·Enrolling By Invitation

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

13 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting

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National Liver Cancer Screening Trial

for Carcinoma, Hepatocellular

18 locations incl. Los Angeles

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 85

Code: NCT06084234·Phase 4·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

38 locations incl. Tucson

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting

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Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

for Breast Cancer

79 locations incl. Phoenix

Sponsor: BriaCell Therapeutics Corporation

Sex: All·Age: 18+

Code: NCT06072612·Phase 3·Recruiting

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Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Durvalumab

536 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06058377·Phase 3·Recruiting

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Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study

for Lung Carcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05802186·Recruiting

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

22 locations incl. Santa Monica

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting

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The PEERLESS II Study

for Pulmonary Embolism

50 locations incl. Birmingham

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT06055920·Recruiting

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Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

for Becker Muscular Dystrophy

24 locations incl. Little Rock

Sponsor: Edgewise Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06066580·Phase 2·Enrolling By Invitation

MindWalk Intervention for Older South Asian Caregivers of People With Cognitive Disabilities (CD)

for Stress, Psychological

8 locations incl. Bolingbrook

Sponsor: University of Illinois at Chicago

Sex: All·Age: 45+

Code: NCT06002919·Recruiting

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

60 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

for Barrett Esophagus

5 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 90

Code: NCT06071845·Recruiting

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A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

32 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting

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Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

for Estrogen-receptor-positive Breast Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06062498·Phase 2·Recruiting

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RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant

for Lung Transplant

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05950724·EARLY_Phase 1·Enrolling By Invitation

Physical Activity Intervention Among Older Women With Gynecologic Cancers (Fit4Treatment)

for Ovary Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 60+

Code: NCT05743517·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

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Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

for Primary Biliary Cholangitis

49 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06051617·Phase 3·Recruiting

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Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

for cGVHD

32 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05919511·Recruiting

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A Validation Study to Evaluate the Performance of Caption Health Lung Guidance and Interpretation

for Shortness of Breath

4 locations incl. New Haven

Sponsor: Caption Health, Inc.

Sex: All·Age: 18+

Code: NCT05992324·Recruiting

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Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

for Advanced Adenocarcinoma

9 locations incl. Irvine

Sponsor: BioAtla, Inc.

Sex: All·Age: 18+

Code: NCT05808634·Phase 1·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy

for Esophagectomy

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 89

Code: NCT05950438·Recruiting

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Preoperative Weight Loss for Open Abdominal Wall Reconstruction

for Abdominal Wall Hernia

2 locations incl. Chicago

Sponsor: Benjamin T. Miller

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05925959·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

for Prostate Adenocarcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT05852041·EARLY_Phase 1·Recruiting

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Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

for Stroke

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06598150·Recruiting

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

9 locations incl. Duarte

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

454 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting

Apply to this trial