Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.
Part of paid clinical trials in Irvine, California.
- Sponsor
- BioAtla, Inc.
- Study ID
- NCT05808634
- Phase
- PHASE1
- Status
- Recruiting
Conditions
- Advanced Adenocarcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- BA3182 — DRUGConditionally active biologic (CAB)-bispecific T-cell engager antibody construct targeting EpCAM
Study Details
The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma
Key Dates
- Start date
- Jul 14, 2023
- Status verified
- Sep 2025
- Primary completion
- Sep 15, 2028
- Completion
- Sep 15, 2028
Study Design
- Enrollment
- 168 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: BA3182All Patients will receive BA3182
Primary Outcome Measure
Part 1: Assess dose limiting toxicity as defined in the protocol [ Time Frame: Up to 24 months ]
Central Contacts
- BioAtla Medical Affairs858-558-0708
Locations (9)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| UC Irvine | Irvine | California | 92697 | |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | |
| Yale Cancer Center | New Haven | Connecticut | 06511 | |
| Northwestern University | Chicago | Illinois | 60611 | |
| University of Illinois | Chicago | Illinois | 60612 | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | |
| The Christ Hospital Cancer Center | Cincinnati | Ohio | 45219 | |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | |
| Fred Hutch Cancer Center | Seattle | Washington | 98109 |
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