Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for Multiple Myeloma

11 locations incl. Goodyear

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225738·Recruiting

Apply to this trial

AI-driven Total Parenteral Nutrition Platform

for Intestinal Failure

1 location in Stanford

Sponsor: Takeoff41, Inc.

Sex: All·Age: Up to 6 Months

Code: NCT07414576·Recruiting

Apply to this trial

Randomized Trial of SGLT2i in Heart Transplant Recipients

for Heart Transplant

6 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT06625073·Phase 4·Recruiting

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Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery

for Myopia

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 22 - 59·Accepts healthy volunteers

Code: NCT07078799·Recruiting

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

13 locations incl. Little Rock

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting

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A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis

for Dermatitis, Atopic

12 locations incl. Houston

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07230860·Phase 2·Recruiting

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Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies

for Breast Biopsy

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Female·Age: 18+

Code: NCT07310004·Recruiting

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Sleep and Morning Wellbeing Study

for Sleep

1 location in San Francisco

Sponsor: Athletic Greens International

Sex: All·Age: 22 - 59·Accepts healthy volunteers

Code: NCT07311434·Recruiting

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Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for Pneumococcal Immunization

13 locations incl. Fayetteville

Sponsor: Sanofi

Sex: All·Age: 42 Days - 89 Days·Accepts healthy volunteers

Code: NCT07348692·Phase 3·Recruiting

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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

for Severe Asthma

13 locations incl. Bakersfield

Sponsor: Generate Biomedicines

Sex: All·Age: 12 - 80

Code: NCT07359846·Phase 3·Recruiting

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Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder

for Major Depressive Disorder (MDD)

1 location in Garden Grove

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70

Code: NCT07226661·Phase 2·Recruiting

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Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use

for Postoperative Pain

1 location in Irvine

Sponsor: Elixir MD Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07311889·Enrolling By Invitation

Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)

for Gastrointestinal Discomfort

1 location in San Francisco

Sponsor: Koralo GmbH

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07407777·Recruiting

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Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology

for Muscle-Invasive Bladder Carcinoma

1 location in Los Angeles

Sponsor: Leslie Ballas

Sex: All·Age: 18+

Code: NCT06417190·Phase 2·Recruiting

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Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

for Lupus Nephritis

11 locations incl. Gilbert

Sponsor: Autolus Limited

Sex: All·Age: 12 - 65

Code: NCT07053800·Phase 2·Recruiting

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Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

for Congenital Heart Disease

8 locations incl. Los Angeles

Sponsor: Starlight Cardiovascular Inc

Sex: All·Age: 1 Minute - 6 Months

Code: NCT07114718·Recruiting

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A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

Drug: Duvakitug

21 locations incl. Coronado

Sponsor: Sanofi

Sex: All·Age: 16 - 80

Code: NCT07185009·Phase 3·Recruiting

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Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

for Non-small Cell Lung Cancer

29 locations incl. Fresno

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07195695·Phase 3·Recruiting

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Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

for Neoplasms

Drug: Nivolumab

4 locations incl. Los Angeles

Sponsor: Corcept Therapeutics

Sex: All·Age: 18+

Code: NCT07276373·Phase 1, Phase 2·Recruiting

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A Study of Revumenib and Mezigdomide in People With Leukemia

for Leukemia

Drug: Mezigdomide

10 locations incl. Duarte

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 12+

Code: NCT07356154·Phase 1, Phase 2·Recruiting

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Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma

for Meningioma of Brain

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07418775·Recruiting

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Vibrotactile Coordinated Reset for the Treatment of Chronic Stroke

for Chronic Stroke

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 80

Code: NCT05490277·Not Yet Recruiting

Parathyroid Allotransplant for Treatment of Hypoparathyroidism

for Hypoparathyroidism

1 location in San Francisco

Sponsor: Peter Stock

Sex: All·Age: 18+

Code: NCT06961071·Phase 1, Phase 2·Recruiting

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Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs

for Diabetes Mellitus

3 locations incl. San Luis Obispo

Sponsor: California Polytechnic State University-San Luis Obispo

Sex: Female·Age: 18+

Code: NCT06988306·Recruiting

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Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)

for Heart Failure

4 locations incl. Los Angeles

Sponsor: Echosens

Sex: All·Age: 18+

Code: NCT07222813·Not Yet Recruiting

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

for Chronic Inducible Urticaria

26 locations incl. Birmingham

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07266402·Phase 3·Recruiting

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Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

for Phantom Limb Syndrome With Pain

4 locations incl. Sacramento

Sponsor: The Ketamine Research Foundation

Sex: All·Age: 18 - 65

Code: NCT07276542·Phase 2, Phase 3·Recruiting

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Frozen Shoulder and Hormone Replacement Therapy

for Adhesive Capsulitis of the Shoulder

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Female·Age: 40+

Code: NCT07278323·Phase 4·Recruiting

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App-Based Certified Diabetes Education Therapy (AB-CDE)

for Type 1 Diabetes (T1D)

6 locations incl. La Jolla

Sponsor: Oregon Health and Science University

Sex: All·Age: 18+

Code: NCT07282639·Not Yet Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for Colorectal Cancer

8 locations incl. Duarte

Sponsor: Cartography Biosciences

Sex: All·Age: 18+

Code: NCT07321106·Phase 1·Recruiting

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A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Searcy

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07321873·Phase 2·Recruiting

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NQ Square TMS for MDD 1Dx3S Adults Multi-site Sham-controlled Protocol

for Major Depressive Disorder

2 locations incl. Campbell

Sponsor: NeuroQore Inc.

Sex: All·Age: 22 - 85

Code: NCT07369180·Enrolling By Invitation

A Clinical Trial of PepZinGI® for Acute Heartburn Relief and Sleep Outcomes

for Heartburn

1 location in San Francisco

Sponsor: NutriScience Innovations, LLC

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07379645·Recruiting

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A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus (T2DM)

1 location in Chula Vista

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07465224·Phase 2·Recruiting

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A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

for Multiple Myeloma

7 locations incl. Mobile

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06980480·Phase 3·Recruiting

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Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

for Hematologic Malignancies

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07186192·Phase 3·Recruiting

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A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)

for Chronic Hepatitis D Infection

8 locations incl. Davis

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18 - 99

Code: NCT07298330·Phase 3·Recruiting

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Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

for Multiple Sclerosis

Drug: Frexalimab

21 locations incl. Cullman

Sponsor: Sanofi

Sex: All·Age: 18 - 60

Code: NCT07325292·Phase 3·Recruiting

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Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for Fibromyalgia

16 locations incl. Little Rock

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07398417·Phase 3·Recruiting

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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

14 locations incl. Madera

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting

Apply to this trial