Paid Clinical Trials in California

California has 6,497 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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6,497 clinical trials

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A Study of JADE101 in Participants With Immunoglobulin A Nephropathy

for IgA Nephropathy

6 locations incl. Chula Vista

Sponsor: Jade Biosciences, Inc.

Sex: All·Age: 18 - 60

Code: NCT07541287·Phase 2·Recruiting

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Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration

for Neovascular (Wet) Age-Related Macular Degeneration

5 locations incl. Beverly Hills

Sponsor: Eyconis INC.

Sex: All·Age: 50+

Code: NCT07587515·Phase 1, Phase 2·Recruiting

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Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

for Major Depressive Disorder

25 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06705478·Phase 2·Recruiting

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Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

8 locations incl. Orange

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 60+

Code: NCT06773936·Phase 2·Enrolling By Invitation

Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

for Toxicant Induced Chronic Multisymptom Illness and Associated Symptoms and Comorbidities

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 65

Code: NCT06962657·Phase 2·Not Yet Recruiting

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer

4 locations incl. Duarte

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07476287·Phase 2·Recruiting

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Pulsed Electric Field Ablation for Metastatic Breast Cancer

for Metastatic Breast Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07487844·Not Yet Recruiting

ANCHOR Validation Trial in High-Risk Multidisciplinary Care

for High-Risk Multidisciplinary Care

1 location in San Francisco

Sponsor: Waymark

Sex: All·Age: 18+

Code: NCT07597499·Recruiting

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AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

12 locations incl. Loma Linda

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting

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Acceptability and Feasibility Study of Non-alcoholic Beverages

for Alcohol Use Disorder (AUD)

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 21 - 89

Code: NCT07451574·Enrolling By Invitation

Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the Circulation

for Liver Transplant

10 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 13

Code: NCT07549503·Phase 2·Recruiting

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A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

for Diabetic Macular Edema

30 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07553429·Phase 1, Phase 2·Recruiting

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Phase Ib/II Platform Study of Multiple Anti-Cancer Agents in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

9 locations incl. Encino

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 99

Code: NCT07590934·Phase 1, Phase 2·Not Yet Recruiting

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

for Locally Advanced Pancreatic Adenocarcinoma

274 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06998940·Phase 3·Recruiting

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Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor

for Gastrointestinal Stromal Tumors

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT07171203·Phase 1·Recruiting

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Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System

for Type 2 Diabetes Mellitus

12 locations incl. Los Angeles

Sponsor: Insulet Corporation

Sex: All·Age: 14 - 75

Code: NCT07579702·Recruiting

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

14 locations incl. Sacramento

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting

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A Study of TAK-505 in Adults With Solid Tumors

for Malignant Solid Tumors

15 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07436728·Phase 1, Phase 2·Recruiting

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: INCA036978

22 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting

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Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

for Prostate Adenocarcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male·Age: 40+

Code: NCT07468903·Recruiting

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An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

Drug: Pelacarsen

115 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting

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Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

for Urothelial Cancer

9 locations incl. Santa Barbara

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07566156·Phase 3·Recruiting

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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

for Obesity

Drug: NNC0487-0111

202 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07567001·Phase 3·Not Yet Recruiting

Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms

for Fatigue

1 location in Del Mar

Sponsor: Radicle Science

Sex: Female·Age: 35 - 60·Accepts healthy volunteers

Code: NCT07572578·Not Yet Recruiting

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

for Obesity or Overweight

39 locations incl. Pelham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07575399·Phase 3·Recruiting

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A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

for Overweight

48 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07575932·Phase 2·Recruiting

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A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

for Major Depressive Disorder

27 locations incl. Gilbert

Sponsor: Definium Therapeutics US, Inc.

Sex: All·Age: 18 - 74

Code: NCT07592689·Phase 3·Recruiting

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A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

3 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07020533·Phase 1·Recruiting

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A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants

for Gout

Drug: Dotinurad

17 locations incl. Granada Hills

Sponsor: Crystalys Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07535034·Phase 2·Recruiting

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An Open-label Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)

for LMNA-Related Dilated Cardiomyopathy

1 location in Los Angeles

Sponsor: Nuevocor Pte. Ltd.

Sex: All·Age: 18+

Code: NCT07606274·Phase 1, Phase 2·Not Yet Recruiting

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

for Hypertension (HTN)

Drug: QCZ484

6 locations incl. Garden Grove

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07543120·Phase 2·Recruiting

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Cemiplimab Plus Gemcitabine in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Ductal Adenocarcinoma (mPDAC)

Drug: Cemiplimab

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT06790602·Phase 2·Recruiting

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A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

for Solid Tumors

Drug: Adagrasib

17 locations incl. Phoenix

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07415031·Phase 2·Recruiting

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A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

for Irritable Bowel Syndrome

Drug: Brenipatide

14 locations incl. Mesa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07545759·Phase 2·Recruiting

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

14 locations incl. Birmingham

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting

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A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

for Type 2 Diabetes

6 locations incl. Lincoln

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07606066·Recruiting

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Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

for Posterior Fossa Ependymal Tumor

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 39

Code: NCT07226453·Phase 2·Recruiting

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Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

12 locations incl. Springdale

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

10 locations incl. Birmingham

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting

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AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

17 locations incl. San Diego

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571005·Phase 3·Recruiting

Apply to this trial