Ferric Citrate and Chronic Kidney Disease in Childrenfor Chronic Kidney Diseases18 locations incl. Los AngelesSponsor: University of California, Los AngelesSex: All·Age: 6 - 18Code: NCT04741646·Phase 2·RecruitingApply to this trial
A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)for Phenylketonuria (PKU)12 locations incl. AuroraSponsor: BioMarin PharmaceuticalSex: All·Age: All agesCode: NCT05813678·RecruitingApply to this trial
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemiafor Relapsed Adult AML20 locations incl. BirminghamSponsor: Massachusetts General HospitalSex: All·Age: 18 - 120·Accepts healthy volunteersCode: NCT05237258·RecruitingApply to this trial
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patientsfor Arrythmia19 locations incl. PhoenixSponsor: University of RochesterSex: All·Age: 18+Code: NCT05034432·Phase 4·RecruitingApply to this trial
The CONFORM Pivotal Trialfor Atrial Fibrillation76 locations incl. BirminghamSponsor: Conformal Medical, IncSex: All·Age: 18+Code: NCT05147792·RecruitingApply to this trial
Open-label Study of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis (sHLH)for Secondary Hemophagocytic Lymphohistiocytosis (sHLH)18 locations incl. BirminghamSponsor: Electra Therapeutics Inc.Sex: All·Age: 6+Code: NCT05416307·Phase 2, Phase 3·RecruitingApply to this trial
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitisfor Autoimmune EncephalitisDrug: Inebilizumab35 locations incl. BirminghamSponsor: University of UtahSex: All·Age: 12+Code: NCT04372615·Phase 2·RecruitingApply to this trial
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucelfor Multiple Myeloma28 locations incl. PhoenixSponsor: Janssen Research & Development, LLCSex: All·Age: 18+Code: NCT05201781·Phase 4·RecruitingApply to this trial
An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophreniafor SchizophreniaDrug: KarXT79 locations incl. PhoenixSponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb companySex: All·Age: 18 - 65Code: NCT05304767·Phase 3·RecruitingApply to this trial
FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancerfor Breast Cancer8 locations incl. La JollaSponsor: Regor Pharmaceuticals Inc.Sex: All·Age: 18+Code: NCT05304962·Phase 1·RecruitingApply to this trial
Telemedicine in Early Childhood Constraint Therapy in Cerebral Palsyfor Cerebral Palsy4 locations incl. AtlantaSponsor: Emory UniversitySex: All·Age: 4 Months - 13 MonthsCode: NCT04997109·RecruitingApply to this trial
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)for Mitral Valve Regurgitation24 locations incl. Los AngelesSponsor: Annetine GelijnsSex: All·Age: 60+Code: NCT05051033·RecruitingApply to this trial
InSpace Accelerated Rehabilitation Studyfor Rotator Cuff Tears11 locations incl. PhoenixSponsor: Stryker EndoscopySex: All·Age: 65+·Accepts healthy volunteersCode: NCT05329584·RecruitingApply to this trial
Study in Parkinson Disease of Exercisefor Parkinson Disease24 locations incl. BirminghamSponsor: Northwestern UniversitySex: All·Age: 40 - 80Code: NCT04284436·RecruitingApply to this trial
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumorsfor Diffuse Midline Glioma (DMG)5 locations incl. San FranciscoSponsor: Sabine Mueller, MD, PhDSex: All·Age: 2 - 21Code: NCT04732065·Phase 1·RecruitingApply to this trial
Trial of Therapeutic Hypothermia in Patients With ARDSfor Respiratory Distress Syndrome, Adult19 locations incl. Los AngelesSponsor: University of Maryland, BaltimoreSex: All·Age: 18 - 85Code: NCT04545424·Phase 2·RecruitingApply to this trial
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïvefor Superficial Bladder Cancer49 locations incl. BirminghamSponsor: enGene, Inc.Sex: All·Age: 18+Code: NCT04752722·Phase 1, Phase 2·RecruitingApply to this trial
REVEAL Biomarkers of Engraftment After Alternative Donor HSCTfor Primary Graft Failure4 locations incl. AtlantaSponsor: University of OklahomaSex: All·Age: 4 - 80Code: NCT03541889·Phase 1·RecruitingApply to this trial
The ENCIRCLE Trialfor Mitral Regurgitation56 locations incl. HuntsvilleSponsor: Edwards LifesciencesSex: All·Age: 18+Code: NCT04153292·RecruitingApply to this trial
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectivenessfor Aortic Dissection31 locations incl. BirminghamSponsor: Endospan Ltd.Sex: All·Age: 18+Code: NCT04471909·RecruitingApply to this trial
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adultsfor Cognitive Impairment, Mild102 locations incl. BirminghamSponsor: Duke UniversitySex: All·Age: 75+·Accepts healthy volunteersCode: NCT04262206·Phase 4·RecruitingApply to this trial
Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndromefor Myelodysplastic Syndromes7 locations incl. JacksonvilleSponsor: Syntrix Biosystems, Inc.Sex: All·Age: 18+Code: NCT04245397·Phase 1·RecruitingApply to this trial
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancerfor Prostate Cancer25 locations incl. DuarteSponsor: AmgenSex: Male·Age: 18+Code: NCT04221542·Phase 1·RecruitingApply to this trial
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)for Frontotemporal Lobar Degeneration (FTLD)25 locations incl. BirminghamSponsor: Mayo ClinicSex: All·Age: 18+·Accepts healthy volunteersCode: NCT04363684·RecruitingApply to this trial
Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanomafor Cutaneous Melanoma, Stage II130 locations incl. MobileSponsor: Melanoma and Skin Cancer Trials LimitedSex: All·Age: 18+Code: NCT03860883·RecruitingApply to this trial
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosisfor Myelofibrosis32 locations incl. BirminghamSponsor: Sumitomo Pharma America, Inc.Sex: All·Age: 18+Code: NCT04176198·Phase 1, Phase 2·RecruitingApply to this trial
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABGfor Atrial Fibrillation51 locations incl. Little RockSponsor: Icahn School of Medicine at Mount SinaiSex: All·Age: 18+Code: NCT04045665·Phase 3·RecruitingApply to this trial
Prophylactic Reinforcement of Ventral Abdominal Incisions Trialfor Open Midline Laparotomy30 locations incl. PhoenixSponsor: C. R. BardSex: All·Age: 18+Code: NCT03911700·RecruitingApply to this trial
Brain Stimulation and Decision-makingfor Depression1 location in AtlantaSponsor: Emory UniversitySex: All·Age: 18 - 50·Accepts healthy volunteersCode: NCT04099056·RecruitingApply to this trial
Von Willebrand Factor in Pregnancy (VIP) Studyfor Von Willebrand Diseases11 locations incl. AuroraSponsor: University of WashingtonSex: Female·Age: 18+Code: NCT04146376·RecruitingApply to this trial
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depressionfor Treatment Resistant Depression98 locations incl. BirminghamSponsor: LivaNovaSex: All·Age: 18+Code: NCT03887715·RecruitingApply to this trial
Stroke Thrombectomy and Aneurysm Registryfor Stroke54 locations incl. BirminghamSponsor: Medical University of South CarolinaSex: All·Age: 1 - 120Code: NCT04994756·RecruitingApply to this trial
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Studyfor Stroke45 locations incl. TucsonSponsor: W.L.Gore & AssociatesSex: All·Age: 18 - 70Code: NCT03821129·RecruitingApply to this trial
A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignanciesfor Acute Myeloid Leukemia11 locations incl. DuarteSponsor: Orca Biosystems, Inc.Sex: All·Age: 12 - 78Code: NCT03802695·Phase 1·RecruitingApply to this trial
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemiafor Leukemia, Myeloid, AcuteDrug: Tuspetinib15 locations incl. BirminghamSponsor: Aptose Biosciences Inc.Sex: All·Age: 18+Code: NCT03850574·Phase 1, Phase 2·RecruitingApply to this trial
ProACT Post-Approval Studyfor Stress Urinary Incontinence6 locations incl. DenverSponsor: UromedicaSex: Male·Age: 50+·Accepts healthy volunteersCode: NCT03767595·RecruitingApply to this trial
North American Prodromal Synucleinopathy Consortiumfor REM Sleep Behavior Disorder9 locations incl. Sun CitySponsor: Washington University School of MedicineSex: All·Age: 18+Code: NCT03623672·Enrolling By Invitation
Longitudinal Early-onset Alzheimer's Disease Study Protocolfor Early Onset Alzheimer Disease18 locations incl. Sun CitySponsor: Indiana UniversitySex: All·Age: 40 - 64·Accepts healthy volunteersCode: NCT03507257·RecruitingApply to this trial
Gastroschisis Outcomes of Delivery (GOOD) Studyfor Gastroschisis38 locations incl. PhoenixSponsor: Medical College of WisconsinSex: Female·Age: 18+Code: NCT02774746·RecruitingApply to this trial
Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancerfor Triple Negative Breast Cancer3 locations incl. AtlantaSponsor: Eileen ConnollySex: Female·Age: 21 - 80Code: NCT02977468·Phase 1·RecruitingApply to this trial