Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVIDfor Long COVIDDrug: Baricitinib17 locations incl. TucsonSponsor: Wes ElySex: All·Age: 18+Code: NCT06631287·Phase 3·RecruitingApply to this trial
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minoritiesfor Coronary Artery Disease18 locations incl. GlendaleSponsor: Weill Medical College of Cornell UniversitySex: All·Age: 18+Code: NCT06399705·Phase 3·RecruitingApply to this trial
Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphomafor Peripheral T-Cell Lymphoma, Not Otherwise SpecifiedDrug: Soquelitinib21 locations incl. DuarteSponsor: Corvus Pharmaceuticals, Inc.Sex: All·Age: 18+Code: NCT06561048·Phase 3·RecruitingApply to this trial
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancerfor Intermediate Risk Non-Muscle Invasive Bladder CancerDrug: Nadofaragene Firadenovec49 locations incl. MobileSponsor: Ferring PharmaceuticalsSex: All·Age: 18+Code: NCT06510374·Phase 3·RecruitingApply to this trial
Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Usefor Opioid Use Disorder4 locations incl. Washington D.C.Sponsor: Elana RosenthalSex: All·Age: 18+Code: NCT06513156·RecruitingApply to this trial
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancerfor Non-muscle Invasive Bladder Cancer With Carcinoma in SituDrug: Nadofaragene Firadenovec38 locations incl. TucsonSponsor: Ferring PharmaceuticalsSex: All·Age: 18+Code: NCT06545955·Phase 3·RecruitingApply to this trial
Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficultyfor Body Composition2 locations incl. OrlandoSponsor: Nemours Children's ClinicSex: All·Age: 1 Week - 10 Weeks·Accepts healthy volunteersCode: NCT04599010·RecruitingApply to this trial
Bionic Pancreas in CFRDfor Cystic Fibrosis-related Diabetes16 locations incl. AuroraSponsor: Jaeb Center for Health ResearchSex: All·Age: 14+Code: NCT06449677·Phase 3·RecruitingApply to this trial
A Study of Obexelimab in Patients With Systemic Lupus Erythematosusfor Systemic Lupus Erythematosus16 locations incl. FresnoSponsor: Zenas BioPharma (USA), LLCSex: All·Age: 18 - 70Code: NCT06559163·Phase 2·RecruitingApply to this trial
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Womenfor Coronary Artery Disease18 locations incl. GlendaleSponsor: Weill Medical College of Cornell UniversitySex: All·Age: 18+Code: NCT06399692·Phase 3·RecruitingApply to this trial
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBCfor High-Risk Non-Muscle-Invasive Bladder Cancer65 locations incl. PhoenixSponsor: CG Oncology, Inc.Sex: All·Age: 18+Code: NCT06567743·Phase 2·RecruitingApply to this trial
PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEmfor Coronary Artery Disease18 locations incl. ChandlerSponsor: Kardion IncSex: All·Age: 18 - 90Code: NCT06445608·RecruitingApply to this trial
CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fractionfor Ischemic Heart Failure5 locations incl. ClearwaterSponsor: BioCardia, Inc.Sex: All·Age: 21 - 90Code: NCT06258447·RecruitingApply to this trial
Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patientsfor MRI Scan1 location in AtlantaSponsor: Songqi GaoSex: Male·Age: 18 - 90Code: NCT06262139·Phase 1, Phase 2·RecruitingApply to this trial
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRTfor Regional Citrate Anticoagulation (RCA)14 locations incl. BirminghamSponsor: Vantive Health LLCSex: All·Age: 18+Code: NCT05399537·Phase 3·RecruitingApply to this trial
SOC Chemotherapy +/- Tocilizumab for Triple Negative and ER-low Breast Cancersfor Metastatic Breast CancerDrug: Tocilizumab6 locations incl. AtlantaSponsor: Kathy MillerSex: All·Age: 18+Code: NCT05846789·Phase 2·RecruitingApply to this trial
VasoStar Vibrational Guidewire System to Facilitate Crossing Coronary Artery Chronic Total Occlusionsfor Chronic Total Occlusion of Coronary Artery2 locations incl. AtlantaSponsor: VasoStar, LLCSex: All·Age: 18+Code: NCT06193954·RecruitingApply to this trial
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemiafor AML With Gene Mutations12 locations incl. Los AngelesSponsor: Lomond Therapeutics Holdings, Inc.Sex: All·Age: 18+Code: NCT06366789·Phase 1·RecruitingApply to this trial
A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapyfor Neuroendocrine Tumors4 locations incl. AtlantaSponsor: Chimeric TherapeuticsSex: All·Age: 18 - 85Code: NCT06055439·Phase 1, Phase 2·RecruitingApply to this trial
Inspiring Seniors Towards Exercise Promotion to Protect Cognitionfor Alzheimer Disease2 locations incl. AtlantaSponsor: Emory UniversitySex: All·Age: 65+·Accepts healthy volunteersCode: NCT06496425·RecruitingApply to this trial
Preventing Injured Knees From osteoArthritis: Severity Outcomesfor Osteoarthritis, Knee9 locations incl. AtlantaSponsor: Brigham and Women's HospitalSex: All·Age: 18 - 45Code: NCT06096259·Phase 2·RecruitingApply to this trial
A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)for Homocystinuria13 locations incl. PhoenixSponsor: Travere Therapeutics, Inc.Sex: All·Age: 5 - 65Code: NCT06431893·Phase 3·Enrolling By Invitation
An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Genefor Stargardt14 locations incl. San DiegoSponsor: Splice BioSex: All·Age: 12 - 65Code: NCT06435000·RecruitingApply to this trial
Promoting Shared Decision Making for Severe Aortic Stenosisfor Aortic Stenosis8 locations incl. San FranciscoSponsor: Massachusetts General HospitalSex: All·Age: 65 - 85Code: NCT06171737·Enrolling By Invitation
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Diseasefor Crohn's Disease15 locations incl. Los AngelesSponsor: Eli Lilly and CompanySex: All·Age: 2 - 17Code: NCT05509777·Phase 3·RecruitingApply to this trial
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Diseasefor Crohn's DiseaseDrug: Guselkumab14 locations incl. Los AngelesSponsor: Janssen Research & Development, LLCSex: All·Age: 2 - 17Code: NCT05923073·Phase 3·RecruitingApply to this trial
T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancerfor Prostate Cancer2 locations incl. AtlantaSponsor: Medical University of South CarolinaSex: Male·Age: 18+Code: NCT05586360·Phase 2·RecruitingApply to this trial
Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infantsfor Premature Birth2 locations incl. AtlantaSponsor: Thrive Neuromedical, LLCSex: All·Age: 32 Weeks - 35 Weeks·Accepts healthy volunteersCode: NCT06063122·RecruitingApply to this trial
Incremental Hemodialysis: The TwoPlus Trialfor End-Stage Kidney Disease10 locations incl. JacksonvilleSponsor: Wake Forest University Health SciencesSex: All·Age: 18+Code: NCT05828823·RecruitingApply to this trial
Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3for Withdrawal Symptoms6 locations incl. AtlantaSponsor: Emory UniversitySex: All·Age: 18 - 75Code: NCT05834478·Phase 3·RecruitingApply to this trial
A Global Prospective Observational Registry of Patients With Pompe Diseasefor Pompe Disease15 locations incl. Little RockSponsor: Amicus TherapeuticsSex: All·Age: All agesCode: NCT06121011·RecruitingApply to this trial
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosusfor Systemic Lupus Erythematosus21 locations incl. OrangeSponsor: Cabaletta BioSex: All·Age: 18 - 65Code: NCT06121297·Phase 1, Phase 2·RecruitingApply to this trial
AB Gait Estim Neurophysiologyfor Gait1 location in AtlantaSponsor: Emory UniversitySex: All·Age: 18 - 65·Accepts healthy volunteersCode: NCT06430164·RecruitingApply to this trial
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitisfor Antineutrophil Cytoplasmic Antibody-associated VasculitisDrug: Avacopan60 locations incl. AnchorageSponsor: AmgenSex: All·Age: 18 - 100Code: NCT06072482·Phase 4·RecruitingApply to this trial
A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CFfor Cystic Fibrosis13 locations incl. BirminghamSponsor: ReCode TherapeuticsSex: All·Age: 18 - 60·Accepts healthy volunteersCode: NCT06237335·Phase 2·RecruitingApply to this trial
Phase 1/2a Study of ANPD001 in Parkinson Diseasefor Parkinson Disease9 locations incl. TucsonSponsor: Aspen NeuroscienceSex: All·Age: 40 - 75Code: NCT06344026·Phase 1·Enrolling By Invitation
The OBSERVE Protocolfor Major Depression Disorder6 locations incl. MilfordSponsor: Yale UniversitySex: All·Age: All agesCode: NCT06725277·RecruitingApply to this trial
A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)for Phenylketonuria (PKU)11 locations incl. AuroraSponsor: BioMarin PharmaceuticalSex: All·Age: All agesCode: NCT06305234·RecruitingApply to this trial
A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinomafor Metastatic Head-and-neck Squamous-cell Carcinoma28 locations incl. GilbertSponsor: AVEO Pharmaceuticals, Inc.Sex: All·Age: 18+Code: NCT06064877·Phase 3·RecruitingApply to this trial
A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatmentfor Homocystinuria13 locations incl. PhoenixSponsor: Travere Therapeutics, Inc.Sex: All·Age: 12 - 65Code: NCT06247085·Phase 3·RecruitingApply to this trial