Clinical Trials at University of Michigan

As of June 2026, 435 paid clinical trials are recruiting at University of Michigan, located at 1500 E MEDICAL CENTER DR, ANN ARBOR, MI 48109-5000, phone (734) 615-9888 in Ann Arbor, Michigan. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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435 clinical trials at University of Michigan

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Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

for Arrhythmogenic Cardiomyopathy

1 location in Ann Arbor

Sponsor: Lexeo Therapeutics

Sex: All·Age: 18 - 67

Code: NCT07050160·Enrolling By Invitation

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

for Renal Cell Carcinoma

5 locations incl. Boston

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06966024·Phase 1·Recruiting

Apply to this trial

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for PIK3CA Mutation

51 locations incl. Gilbert

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06982521·Phase 3·Recruiting

Apply to this trial

A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation

for Constipation

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07032376·Enrolling By Invitation

Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction

for ACL

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 14 - 45

Code: NCT06529692·Recruiting

Apply to this trial

Store Safely: Rural Firearm Injury Prevention for Families

for Firearm Injury

2 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06719713·Recruiting

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Transcranial Alternating Current Stimulation (tACS) in Stuttering

for Stuttering, Adult

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 65

Code: NCT06740968·Recruiting

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Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

for Aphasia Following Cerebral Infarction

2 locations incl. Ann Arbor

Sponsor: Syracuse University

Sex: All·Age: 18+

Code: NCT07151677·Recruiting

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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

for Adjustment Disorder

30 locations incl. Birmingham

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 80

Code: NCT07002034·Phase 2·Recruiting

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Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

for Gastric Adenocarcinoma

17 locations incl. Phoenix

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07021066·Phase 1·Recruiting

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Remote Electrical Stimulation for Pain and Depression Treatment in Cirrhosis

for Cirrhosis

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06932783·Recruiting

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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

for Familial Adenomatous Polyposis (FAP)

18 locations incl. Arcadia

Sponsor: Rapamycin Holdings Inc.

Sex: All·Age: 18+

Code: NCT06950385·Phase 3·Recruiting

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Groundbreaking Renal Assist Device Intervening to ENhance cardioThoracic Surgery Outcomes

for Renal Impairment After Cardiac Surgery

4 locations incl. Weston

Sponsor: 3ive Labs

Sex: All·Age: 22 - 85

Code: NCT07017933·Recruiting

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

18 locations incl. Birmingham

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting

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University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50 - 80

Code: NCT07482475·Recruiting

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

60 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting

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FITting Non-invasive Tests in Lynch Syndrome Surveillance

for Colorectal Cancer

3 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 20 - 80

Code: NCT06898996·Recruiting

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Lebrikizumab in Moderate-to-severe Atopic Dermatitis

for Atopic Dermatitis

2 locations incl. Folsom

Sponsor: Johann E Gudjonsson MD PhD

Sex: All·Age: 18+

Code: NCT06906497·Phase 4·Recruiting

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Postpartum Intervention for Mothers With Opioid Use Disorders (R33)

for Opioid Use Disorder

2 locations incl. Ann Arbor

Sponsor: Stony Brook University

Sex: Female·Age: 18 - 50

Code: NCT07632053·Recruiting

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Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury

for Kidney Injury, Acute

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07016074·Phase 2·Recruiting

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A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

for Pancreatic Ductal Adenocarcinoma

13 locations incl. Los Angeles

Sponsor: Verastem, Inc.

Sex: All·Age: 18+

Code: NCT07020221·Phase 1, Phase 2·Recruiting

Apply to this trial

ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

27 locations incl. Burlingame

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting

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Clinician Satisfaction With the VERABAND™

for Chronic Low-back Pain

3 locations incl. La Jolla

Sponsor: University of Michigan

Sex: All·Age: 18 - 85

Code: NCT06080464·Recruiting

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The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

for Bronchiectasis

80 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT06872892·Phase 3·Recruiting

Apply to this trial

Implant Phenotype Modification Via GBR and ADM

for Horizontal Ridge Deficiency

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07082244·Recruiting

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ADAPT Micro-Randomized Trial

for Cardiovascular Diseases

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06915220·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

for Asthma

Drug: PF-07275315

36 locations incl. Mobile

Sponsor: Pfizer

Sex: All·Age: 18 - 70

Code: NCT06977581·Phase 2·Recruiting

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Training Community Members to be Coaches to Deliver the HealthyLifetime Program

for Health Behaviors

2 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 30+

Code: NCT06616246·Recruiting

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

50 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting

Apply to this trial

Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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Designing and Assessing a Women Only Cardiac Rehabilitation (CARE) Program

for Cardiac Rehabilitation

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Female·Age: 40 - 80

Code: NCT06784895·Recruiting

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Characterization and Analysis of Evoked Cortical Responses in Participants With Medication-intractable Epilepsy

for Intractable Epilepsy

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 22 - 75

Code: NCT07014592·Recruiting

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Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting

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PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for Progressive Pulmonary Fibrosis

5 locations incl. Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18 - 80

Code: NCT06855329·Recruiting

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Family Acceptance Project Online (Pilot RCT)

for LGBTQ

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT06839859·Phase 2·Recruiting

Apply to this trial

Patient-Centered Decision Support for Eosinophilic Esophagitis

for Eosinophilic Esophagitis

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06817213·Recruiting

Apply to this trial

Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease

for Parkinson Disease

1 location in Ann Arbor

Sponsor: Vikas Kotagal

Sex: All·Age: 45+

Code: NCT06679374·Phase 2·Recruiting

Apply to this trial

Intern Health Study 2025

for Depression - Major Depressive Disorder

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07052357·Enrolling By Invitation

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

30 locations incl. Palo Alto

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

9 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting

Apply to this trial