Synced daily from ClinicalTrials.gov via AACT. Last sync: .
18 Zibotentan clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 14 indications (including Liver Cirrhosis & Chronic Kidney Disease) and 3,613 total planned enrollment. 1 Phase 3 Zibotentan trial and 10 Phase 2 are listed. 1 Zibotentan clinical trial is actively recruiting. Most recent activity: NCT06087835 (Feb 2027).
Zibotentan clinical trials at a glance: phase × recruitment status
Phase
recruiting
active not recruiting
completed
terminated
Total
P1
7
7
P2
1
7
2
10
P3
1
1
Recruiting Zibotentan clinical trials (1)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
ZODIACA Study to Investigate the Effects of Zibotentan/Dapagliflozin Combination Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria
Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
A Study to Investigate the Effects of Zibotentan/Dapagliflozin Combination Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria
Assessing the Effect of Multiple Doses of Zibotentan on the Pharmacokinetics of Single Doses of Combined Oral Contraceptives in Healthy Female Participants of Non-childbearing Potential.
Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
A Study to Investigate the Effects of Zibotentan/Dapagliflozin Combination Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria
Assessing the Effect of Multiple Doses of Zibotentan on the Pharmacokinetics of Single Doses of Combined Oral Contraceptives in Healthy Female Participants of Non-childbearing Potential.
18 Zibotentan clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 14 are marked completed.
Are Zibotentan clinical trials recruiting in 2026?
Yes — 1 Zibotentan trial is actively recruiting in 2026. See the recruiting trials and the per-state site list further down this page.
What conditions is Zibotentan being studied for?
Zibotentan is being studied for Liver Cirrhosis, Chronic Kidney Disease, Chronic Kidney Disease With High Proteinuria, Healthy Female Participants, Healthy Participants and 12 more. The trials are grouped by indication on this page.
What phase is Zibotentan in?
Zibotentan clinical trials span 1 Phase 3, 10 Phase 2, 7 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Zibotentan clinical trials?
The lead sponsor across the most Zibotentan trials is AstraZeneca, with 5 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Zibotentanas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.