Tafasitamab Clinical Trials (2026): 50 Studies for Diffuse Large B-cell Lymphoma & Chronic Lymphocytic Leukemia

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

50 Tafasitamab clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 32 indications (including Diffuse Large B-cell Lymphoma & Chronic Lymphocytic Leukemia) and 4,528 total planned enrollment. 4 Phase 3 Tafasitamab trials and 24 Phase 2 are listed. 21 Tafasitamab clinical trials are actively recruiting at 113 U.S. sites across 22 states. Most recent activity: NCT06029309 (May 2032).

Where to Participate: All Tafasitamab Trial Sites in the U.S. (113 sites across 22 states)

Every actively recruiting Tafasitamabtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
AZBanner University Medical Center - TucsonTucson85719NCT05890352Map
AZUniversity of Arizona Cancer Center-North CampusTucson85719NCT05890352Map
CATower Cancer Research FoundationBeverly Hills90211NCT05890352Map
CACity of Hope Comprehensive Cancer CenterDuarte91010NCT05890352Map
CACity of Hope SeacliffHuntington Beach92648NCT05890352Map
CACity of Hope Antelope ValleyLancaster93534NCT05890352Map
CACity of Hope at Long Beach ElmLong Beach90813NCT05890352Map
CACedars Sinai Medical CenterLos Angeles90048NCT05890352Map
CACity of Hope Newport BeachNewport Beach92660NCT05890352Map
CAUniversity of California, San FranciscoSan Francisco94143NCT05351593Map
CACity of Hope South PasadenaSouth Pasadena91030NCT05890352Map
CACity of Hope South BayTorrance90503NCT05890352Map
CACity of Hope UplandUpland91786NCT05890352Map
FLHoly Cross HospitalFort Lauderdale33308NCT05890352Map
FLUniversity of MiamiMiami33136NCT06029309Map
FLMoffitt Cancer CenterTampa33612NCT06760156Map
ILUniversity of Chicago Comprehensive Cancer CenterChicago60637NCT05890352Map
ILUniversity of IllinoisChicago60612NCT05890352Map
ILCarle at The RiverfrontDanville61832NCT05890352Map
ILCarle Physician Group-EffinghamEffingham62401NCT05890352Map
ILCarle Physician Group-Mattoon/CharlestonMattoon61938NCT05890352Map
ILUC Comprehensive Cancer Center at Silver CrossNew Lenox60451NCT05890352Map
ILUniversity of Chicago Medicine-Orland ParkOrland Park60462NCT05890352Map
ILMemorial Hospital EastShiloh62269NCT05890352Map
ILCarle Cancer CenterUrbana61801NCT05890352Map
INNorthwest Cancer Center - Main CampusCrown Point46307NCT05890352Map
INNorthwest Oncology LLCDyer46311NCT05890352Map
INNorthwest Cancer Center - HobartHobart46342NCT05890352Map
INSaint Mary Medical CenterHobart46342NCT05890352Map
INSaint Catherine HospitalIndianapolis46312NCT05890352Map
INThe Community HospitalMunster46321NCT05890352Map
INWomen's Diagnostic Center - MunsterMunster46321NCT05890352Map
INNorthwest Cancer Center - ValparaisoValparaiso46383NCT05890352Map
IAMercy HospitalCedar Rapids52403NCT05890352Map
IAOncology Associates at Mercy Medical CenterCedar Rapids52403NCT05890352Map
IAMercy Medical Center - Des MoinesDes Moines50314NCT05890352Map
MITrinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor48106NCT05890352Map
MITrinity Health IHA Medical Group Hematology Oncology - BrightonBrighton48114NCT05890352Map
MITrinity Health Medical Center - BrightonBrighton48114NCT05890352Map
MITrinity Health IHA Medical Group Hematology Oncology - CantonCanton48188NCT05890352Map
MITrinity Health Medical Center - CantonCanton48188NCT05890352Map
MIChelsea HospitalChelsea48118NCT05890352Map
MITrinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea48118NCT05890352Map
MICancer Hematology Centers - FlintFlint48503NCT05890352Map
MIGenesys Hurley Cancer InstituteFlint48503NCT05890352Map
MIHurley Medical CenterFlint48503NCT05890352Map
MIUniversity of Michigan Health - Sparrow LansingLansing48912NCT05890352Map
MITrinity Health Saint Mary Mercy Livonia HospitalLivonia48154NCT05890352Map
MITrinity Health Saint Joseph Mercy Oakland HospitalPontiac48341NCT05890352Map
MIHuron Gastroenterology PCYpsilanti48106NCT05890352Map
MITrinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti48197NCT05890352Map
MNEssentia Health - Deer River ClinicDeer River56636NCT05890352Map
MNEssentia Health Cancer CenterDuluth55805NCT05890352Map
MNEssentia Health Hibbing ClinicHibbing55746NCT05890352Map
MNMasonic Cancer CenterMinneapolis55455NCT06792825Map
MNMayo Clinic in RochesterRochester55905NCT05910801Map
MNEssentia Health SandstoneSandstone55072NCT05890352Map
MNEssentia Health Virginia ClinicVirginia55792NCT05890352Map
MSUniversity of Mississippi Medical CenterJackson39216NCT05890352Map
MOSiteman Cancer Center at Saint Peters HospitalCity of Saint Peters63376NCT05890352Map
MOSiteman Cancer Center at West County HospitalCreve Coeur63141NCT05890352Map
MOSiteman Cancer Center at Christian HospitalSt Louis63136NCT05890352Map
MOSiteman Cancer Center-South CountySt Louis63129NCT05890352Map
MOWashington University School of MedicineSt Louis63110NCT05890352Map
NJRutgers Cancer Institute of New JerseyNew Brunswick08903NCT05786040Map
NYNYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterNew York10032NCT05890352Map
NYUniversity of RochesterRochester14642NCT05890352Map
NYWilmot Cancer Institute at WebsterWebster14580NCT05890352Map
NCUniversity of North Carolina-Hillsborough CampusHillsborough27278NCT05786040Map
OHOhio State University Comprehensive Cancer CenterColumbus43210NCT05786040Map
OKUniversity of Oklahoma Health Sciences CenterOklahoma City73104NCT05890352Map
ORProvidence Newberg Medical CenterNewberg97132NCT05890352Map
ORProvidence Willamette Falls Medical CenterOregon City97045NCT05890352Map
OROHSU Knight Cancer InstitutePortland97239NCT05943496Map
ORProvidence Portland Medical CenterPortland97213NCT05890352Map
ORProvidence Saint Vincent Medical CenterPortland97225NCT05890352Map
SCMedical University of South CarolinaCharleston29425NCT05890352Map
TXBaylor College of Medicine/Dan L Duncan Comprehensive Cancer CenterHouston77030NCT05890352Map
TXBen Taub General HospitalHouston77030NCT05890352Map
TXM D Anderson Cancer CenterHouston77030NCT05615636Map
TXMD Anderson Cancer CenterHouston77030NCT06434363Map
TXThe University of Texas Health Science Center at HoustonHouston77030NCT06434363Map
TXUniversity of Texas Health Science Center at San AntonioSan Antonio78229NCT05890352Map
UTHuntsman Cancer InstituteSalt Lake City84112NCT05786040Map
UTHuntsman Cancer Institute/University of UtahSalt Lake City84112NCT05890352Map
VAVCU Massey Cancer Center at Stony PointRichmond23235NCT05890352Map
VAVCU Massey Comprehensive Cancer CenterRichmond23298NCT05890352Map
WAFred Hutch/University of Washington Cancer ConsortiumSeattle98109NCT05455697Map
WIThedaCare Regional Cancer CenterAppleton54911NCT05890352Map
WIDuluth Clinic AshlandAshland54806NCT05890352Map
WIAurora Cancer Care-Southern Lakes VLCCBurlington53105NCT05890352Map
WIMarshfield Medical Center-EC Cancer CenterEau Claire54701NCT05890352Map
WIAurora Health Care Germantown Health CenterGermantown53022NCT05890352Map
WIAurora Cancer Care-GraftonGrafton53024NCT05890352Map
WIAurora BayCare Medical CenterGreen Bay54311NCT05890352Map
WIAurora Cancer Care-Kenosha SouthKenosha53142NCT05890352Map
WIGundersen Lutheran Medical CenterLa Crosse54601NCT05890352Map
WIAurora Bay Area Medical Group-MarinetteMarinette54143NCT05890352Map
WIMarshfield Medical Center-MarshfieldMarshfield54449NCT05890352Map
WIAurora Cancer Care-MilwaukeeMilwaukee53209NCT05890352Map
WIAurora Saint Luke's Medical CenterMilwaukee53215NCT05890352Map
WIAurora Sinai Medical CenterMilwaukee53233NCT05890352Map
WIMarshfield Medical Center - MinocquaMinocqua54548NCT05890352Map
WIVince Lombardi Cancer Clinic - OshkoshOshkosh54904NCT05890352Map
WIAurora Cancer Care-RacineRacine53406NCT05890352Map
WIMarshfield Medical Center-Rice LakeRice Lake54868NCT05890352Map
WIVince Lombardi Cancer Clinic-SheboyganSheboygan53081NCT05890352Map
WIMarshfield Medical Center-River Region at Stevens PointStevens Point54482NCT05890352Map
WIAurora Medical Center in SummitSummit53066NCT05890352
WIVince Lombardi Cancer Clinic-Two RiversTwo Rivers54241NCT05890352Map
WIAurora Cancer Care-Milwaukee WestWauwatosa53226NCT05890352Map
WIAurora West Allis Medical CenterWest Allis53227NCT05890352Map
WIMarshfield Medical Center - WestonWeston54476NCT05890352Map

Tafasitamab clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingcompletedterminatedwithdrawnsuspendednot yet recruitingunknownapproved for marketingTotal
Early P111
P111114
P1/P2532313
P21052211324
P2/P311
P3134
N/A1113

Recruiting Tafasitamab clinical trials (21)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT06029309ZANU-TAFAZanubrutinib and Tafasitamab in Mantle Cell LymphomaP1/P2Mantle Cell Lymphoma27May 2024
NCT07126236REPIFIRResponse-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell LymphomaP2Large B Cell Lymphoma80Aug 2025
NCT06792825HM2023-43HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZLP2Follicular Lymphoma65Aug 2025
NCT07585747CUREMZL002A Exploratory Study on Untreated Follicular Lymphoma With Orelabrutinib, Tafasitamab, and LenalidomideP2Follicular Lymphoma27Apr 2026
NCT06434363Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune DisordersP1/P2Autoimmune Disorders47Jul 2024
NCT05910801V-MINDTafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell LymphomaP2Recurrent Mantle Cell Lymphoma100Jan 2024
NCT06521255Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell LymphomaP3DLBCL244May 2024
NCT07502872TPGTPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell LymphomaP2Diffuse Large B Cell Lymphoma30May 2026
NCT07582159Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaP2Chronic Lymphocytic Leukemia35Dec 2026
NCT05366218Anti-CD19-ALLTafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage LeukemiaP1/P2ALL, Childhood B-Cell20Mar 2023
NCT05890352Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to TreatmentP2Grade 3b Follicular Lymphoma227Sep 2023
NCT06760156Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell LymP2Large B-cell Lymphoma28Mar 2025
NCT05943496Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic LymphomaP1Chronic Lymphocytic Leukemia27Oct 2023
NCT07225439NHLRituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)P1Non Hodgkin Lymphoma15Dec 2025
NCT05786040Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative DisorderP2Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder28Mar 2023
NCT06465433Extension Study to Provide Continued Treatment for Patients With Hematologic Malignancies Previously Enrolled in Studies With TafasitamabP2Hematologic Malignancies25Nov 2022
NCT05615636A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHLP2Hodgkin Lymphoma36Apr 2023
NCT05455697Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell LymphomaP1/P2Diffuse Large B-Cell Lymphoma35Jan 2023
NCT05583071MTR²Methotrexate, Tafasitamab, Lenalidomide and Rituximab in Patients With PCNSLP2Non-Hodgkin Lymphoma20Aug 2024
NCT05552937Evaluate the Safety and Efficacy of Tafasitamab Combined With Lenalidomide in Patients With Relapsed or Refractory DLBCLP2DLBCL50Sep 2021
NCT05351593Tafasitamab Plus Lenalidomide in Relapsed CNS LymphomaP1/P2CNS Lymphoma35Jun 2022

Tafasitamab clinical trials by indication

Diffuse Large B-cell Lymphoma (6)

NCTAcronymPhaseStatusTitle
NCT04824092frontMINDP3active not recruitingTafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
NCT04981795realMINDN/AcompletedrealMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL
NCT05883709N/AunknownA Real-world Study of Tafasitamab in Combination With Lenalidomide in Patients withR/R DLBCL
NCT02763319B-MINDP2/P3completedA Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)
NCT02399085L-MINDP2completedOpen Label Study to Evaluate the Safety and Efficacy of Lenalidomide With MOR00208 in Patients With R-R DLBCL
NCT04134936P1completedPhase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCL

Chronic Lymphocytic Leukemia (4)

NCTAcronymPhaseStatusTitle
NCT07582159P2not yet recruitingTafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
NCT05943496P1recruitingTafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
NCT05718869P2active not recruitingTafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, TaZA CLL Study
NCT04809467topMINDP1/P2terminatedA Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)

DLBCL (4)

NCTAcronymPhaseStatusTitle
NCT06521255P3recruitingEvaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04974216P2active not recruitingStudy of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older
NCT05552937P2recruitingEvaluate the Safety and Efficacy of Tafasitamab Combined With Lenalidomide in Patients With Relapsed or Refractory DLBCL
NCT04300803MOR00208N/Aapproved for marketingExpanded Access Program for Tafasitamab (MOR00208) in R/R DLBCL

Follicular Lymphoma (3)

NCTAcronymPhaseStatusTitle
NCT06792825HM2023-43P2recruitingHM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL
NCT07585747CUREMZL002P2not yet recruitingA Exploratory Study on Untreated Follicular Lymphoma With Orelabrutinib, Tafasitamab, and Lenalidomide
NCT04680052InMINDP3active not recruitingA Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.

Diffuse Large B-Cell Lymphoma (3)

NCTAcronymPhaseStatusTitle
NCT05455697P1/P2recruitingTafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma
NCT04978584P2active not recruitingRituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study
NCT05626322PF-07901801P1/P2terminatedEffects of Maplirpacept (PF-07901801),Tafasitamab, and Lenalidomide in People With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B Cell Lymphoma (2)

NCTAcronymPhaseStatusTitle
NCT07502872TPGP2not yet recruitingTPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma
NCT05222555MINDwayP1/P2active not recruitingSafety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL Patients

Mantle Cell Lymphoma (2)

NCTAcronymPhaseStatusTitle
NCT06029309ZANU-TAFAP1/P2recruitingZanubrutinib and Tafasitamab in Mantle Cell Lymphoma
NCT05788289P2terminatedA Study of Tafasitamab and Lenalidomide in People With Mantle Cell Lymphoma

Lymphoma, B-Cell (2)

NCTAcronymPhaseStatusTitle
NCT04882163CC-220P1/P2withdrawnStudy to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell Lymphoma
NCT04161248Early P1active not recruitingPhase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Non Hodgkin Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT07225439NHLP1not yet recruitingRituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT07030699ECLATP2withdrawnA Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma

Large B Cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT07126236REPIFIRP2recruitingResponse-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell Lymphoma

Large B-cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT06760156P2recruitingTafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell Lym

Non-Hodgkin Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05583071MTR²P2recruitingMethotrexate, Tafasitamab, Lenalidomide and Rituximab in Patients With PCNSL

Autoimmune Disorders (1)

NCTAcronymPhaseStatusTitle
NCT06434363P1/P2recruitingPhase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

Chronic Graft Versus Host Disease (1)

NCTAcronymPhaseStatusTitle
NCT05993611P1suspendedAllogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Recurrent Mantle Cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05910801V-MINDP2recruitingTafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

Grade 3b Follicular Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05890352P2recruitingStudy Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

Recurrent B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05821088P2suspendedTafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Hodgkin Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05615636P2recruitingA Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHL

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative (1)

NCTAcronymPhaseStatusTitle
NCT05453500P2active not recruitingChemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

Monomorphic B-Cell Post-Transplant Lymphoproliferative Disorder (1)

NCTAcronymPhaseStatusTitle
NCT05786040P2recruitingTafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative Disorder

ALL, Childhood B-Cell (1)

NCTAcronymPhaseStatusTitle
NCT05366218Anti-CD19-ALLP1/P2recruitingTafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage Leukemia

Large B-Cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05429268firmMINDP3active not recruitingStudy to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (firmMIND)

Hematologic Malignancies (1)

NCTAcronymPhaseStatusTitle
NCT06465433P2recruitingExtension Study to Provide Continued Treatment for Patients With Hematologic Malignancies Previously Enrolled in Studies With Tafasitamab

CNS Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05351593P1/P2recruitingTafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma

Diffuse Large-cell B-cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT05328102DLBCLP2terminatedPhase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)

Relapsed Hematologic Malignancy (1)

NCTAcronymPhaseStatusTitle
NCT05205252ARIAP1/P2withdrawnA Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer.

Marginal Zone Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT04646395P2active not recruitingStudy of Acalabrutinib and Tafasitamab in MZL Patients

Non Hodgkins Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT04661007J-MINDP1/P2active not recruitingTo Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)

Relapsed or Refractory Diffuse Large B-Cell Lymphoma (1)

NCTAcronymPhaseStatusTitle
NCT04607772RRP1/P2withdrawnStudy of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

Lymphoma, Non-Hodgkin (1)

NCTAcronymPhaseStatusTitle
NCT03930953P1/P2active not recruitingA Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)

Leukemia, Lymphocytic, Chronic, B-Cell (1)

NCTAcronymPhaseStatusTitle
NCT02639910COSMOSP2completedStudy to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

Tafasitamab pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
InMINDNCT04680052P3active not recruitingFollicular Lymphoma654PMID 41360064
frontMINDNCT04824092P3active not recruitingDiffuse Large B-cell Lymphoma899PMID 40993016
firmMINDNCT05429268P3active not recruitingLarge B-Cell Lymphoma82
REPIFIRNCT07126236P2recruitingLarge B Cell Lymphoma80
HM2023-43NCT06792825P2recruitingFollicular Lymphoma65
CUREMZL002NCT07585747P2not yet recruitingFollicular Lymphoma27
V-MINDNCT05910801P2recruitingRecurrent Mantle Cell Lymphoma100
TPGNCT07502872P2not yet recruitingDiffuse Large B Cell Lymphoma30
MTR²NCT05583071P2recruitingNon-Hodgkin Lymphoma20
ECLATNCT07030699P2withdrawnLymphoma0
L-MINDNCT02399085P2completedDiffuse Large B-cell Lymphoma81PMID 32511983
DLBCLNCT05328102P2terminatedDiffuse Large-cell B-cell Lymphoma3
COSMOSNCT02639910P2completedLeukemia, Lymphocytic, Chronic, B-Cell24PMID 34414843

Terminated and withdrawn Tafasitamab trials (10)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All Tafasitamab trials (50)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06029309ZANU-TAFAZanubrutinib and Tafasitamab in Mantle Cell LymphomaP1/P2recruiting27Alvaro Alencar, MDMay 2024
NCT07126236REPIFIRResponse-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell LymphomaP2recruiting80Grupo Español de Linfomas y Transplante Autólogo de Médula ÓseaAug 2025
NCT06792825HM2023-43HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZLP2recruiting65Masonic Cancer Center, University of MinnesotaAug 2025
NCT05453500Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic LeukemiaP2active not recruiting32University of WashingtonMar 2023
NCT07585747CUREMZL002A Exploratory Study on Untreated Follicular Lymphoma With Orelabrutinib, Tafasitamab, and LenalidomideP2not yet recruiting27Institute of Hematology & Blood Diseases Hospital, ChinaApr 2026
NCT06434363Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune DisordersP1/P2recruiting47M.D. Anderson Cancer CenterJul 2024
NCT05910801V-MINDTafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell LymphomaP2recruiting100Academic and Community Cancer Research UnitedJan 2024
NCT06521255Evaluate the Safety and Efficacy of Tafasitamab and Lenalidomide in Combination With Gemcitabine and Oxaliplatin Versus Rituximab in Combination With Gemcitabine and Oxaliplatin in Patients With Relapsed/Refractory Diffuse Large B-Cell LymphomaP3recruiting244Beijing InnoCare Pharma Tech Co., Ltd.May 2024
NCT07502872TPGTPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-grade B-cell LymphomaP2not yet recruiting30Brown UniversityMay 2026
NCT07582159Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaP2not yet recruiting35City of Hope Medical CenterDec 2026
NCT04882163CC-220Study to Evaluate Tolerability of Iberdomide (CC-220) in Combination With Polatuzumab Vedotin Plus Rituximab or Tafasitamab or Rituximab Plus Chemotherapy in B-cell LymphomaP1/P2withdrawn0CelgeneOct 2021
NCT05366218Anti-CD19-ALLTafasitamab (MOR00208) in Pediatric Patients With Relapsed or Refractory Acute B Lineage LeukemiaP1/P2recruiting20University Hospital TuebingenMar 2023
NCT05890352Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to TreatmentP2recruiting227SWOG Cancer Research NetworkSep 2023
NCT04680052InMINDA Phase 3 Study to Assess Efficacy and Safety of Tafasitamab Plus Lenalidomide and Rituximab Compared to Placebo Plus Lenalidomide and Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma or Marginal Zone Lymphoma.P3active not recruiting654Incyte CorporationApr 2021
NCT05993611Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell TransplantationP1suspended27City of Hope Medical CenterFeb 2024
NCT04646395Study of Acalabrutinib and Tafasitamab in MZL PatientsP2active not recruiting26International Extranodal Lymphoma Study Group (IELSG)Oct 2021
NCT03930953A Safety and Preliminary Efficacy Study of CC-99282, Alone and in Combination With Anti-lymphoma Agents in Participants With Relapsed or Refractory Non-Hodgkin Lymphomas (R/R NHL)P1/P2active not recruiting438CelgeneMay 2019
NCT06760156Tafasitamab and Lenalidomide as First Salvage Therapy for Residual Large B Cell LymP2recruiting28H. Lee Moffitt Cancer Center and Research InstituteMar 2025
NCT05943496Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic LymphomaP1recruiting27OHSU Knight Cancer InstituteOct 2023
NCT07225439NHLRituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)P1not yet recruiting15Paolo Caimi, MDDec 2025
NCT05786040Tafasitamab and Rituximab for Front-Line Treatment of Post-Transplant Lymphoproliferative DisorderP2recruiting28Timothy VoorheesMar 2023
NCT05222555MINDwaySafety and Pharmacokinetics Study of a Modified Tafasitamab IV Dosing Regimen Combined With Lenalidomide in R-R DLBCL PatientsP1/P2active not recruiting53Incyte CorporationJul 2022
NCT04824092frontMINDTafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL PatientsP3active not recruiting899Incyte CorporationMay 2021
NCT06465433Extension Study to Provide Continued Treatment for Patients With Hematologic Malignancies Previously Enrolled in Studies With TafasitamabP2recruiting25Incyte CorporationNov 2022
NCT05615636A Phase II Trial of Mosunetuzumab, Polatuzumab, Tafasitamab, and Lenalidomide in Patients With Relapsed B-cell NHLP2recruiting36M.D. Anderson Cancer CenterApr 2023
NCT05455697Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell LymphomaP1/P2recruiting35University of WashingtonJan 2023
NCT04974216Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or OlderP2active not recruiting71The Lymphoma Academic Research OrganisationDec 2021
NCT05583071MTR²Methotrexate, Tafasitamab, Lenalidomide and Rituximab in Patients With PCNSLP2recruiting20University of CologneAug 2024
NCT05552937Evaluate the Safety and Efficacy of Tafasitamab Combined With Lenalidomide in Patients With Relapsed or Refractory DLBCLP2recruiting50Beijing InnoCare Pharma Tech Co., Ltd.Sep 2021
NCT05429268firmMINDStudy to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (firmMIND)P3active not recruiting82Incyte CorporationDec 2022
NCT04978584Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop StudyP2active not recruiting62M.D. Anderson Cancer CenterMar 2022
NCT05821088Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell LymphomaP2suspended37David Bond, MDJun 2023
NCT04661007J-MINDTo Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)P1/P2active not recruiting72Incyte Biosciences Japan GKDec 2020
NCT04161248Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell LymphomaEarly P1active not recruiting40Canadian Cancer Trials GroupSep 2020
NCT05718869Tafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, TaZA CLL StudyP2active not recruiting26City of Hope Medical CenterMay 2023
NCT05351593Tafasitamab Plus Lenalidomide in Relapsed CNS LymphomaP1/P2recruiting35James RubensteinJun 2022
NCT07030699ECLATA Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell LymphomaP2withdrawn0Memorial Sloan Kettering Cancer CenterAug 2025
NCT04981795realMINDrealMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCLcompleted102Incyte CorporationSep 2021
NCT04607772RRStudy of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)P1/P2withdrawn0Karyopharm Therapeutics IncNov 2020
NCT05626322PF-07901801Effects of Maplirpacept (PF-07901801),Tafasitamab, and Lenalidomide in People With Relapsed or Refractory Diffuse Large B-cell LymphomaP1/P2terminated6PfizerAug 2023
NCT05883709A Real-world Study of Tafasitamab in Combination With Lenalidomide in Patients withR/R DLBCLunknown15Zhao WeiliJul 2023
NCT04809467topMINDA Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)P1/P2terminated54Incyte CorporationSep 2021
NCT05788289A Study of Tafasitamab and Lenalidomide in People With Mantle Cell LymphomaP2terminated4Memorial Sloan Kettering Cancer CenterMar 2023
NCT02763319B-MINDA Trial to Evaluate the Efficacy and Safety of Tafasitamab With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)P2/P3completed453Incyte CorporationNov 2016
NCT05205252ARIAA Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer.P1/P2withdrawn0Epizyme, Inc.Dec 2021
NCT02399085L-MINDOpen Label Study to Evaluate the Safety and Efficacy of Lenalidomide With MOR00208 in Patients With R-R DLBCLP2completed81MorphoSys AGMar 2016
NCT05328102DLBCLPhase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)P2terminated3Xencor, Inc.Apr 2022
NCT04134936Phase Ib Study to Assess Safety and Preliminary Efficacy of Tafasitamab or Tafasitamab Plus Lenalidomide in Addition to R-CHOP in Patients With Newly Diagnosed DLBCLP1completed66MorphoSys AGDec 2019
NCT02639910COSMOSStudy to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKiP2completed24MorphoSys AGNov 2016
NCT04300803MOR00208Expanded Access Program for Tafasitamab (MOR00208) in R/R DLBCLapproved for marketing0MorphoSys AG

Tafasitamab clinical trials: frequently asked questions

How many Tafasitamab clinical trials are there?
50 Tafasitamab clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 17 are actively recruiting participants. 5 are marked completed.
Are Tafasitamab clinical trials recruiting in 2026?
Yes — 17 Tafasitamab trials are actively recruiting in 2026, with 113 U.S. sites across 22 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Tafasitamab being studied for?
Tafasitamab is being studied for Diffuse Large B-cell Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma and 74 more. The trials are grouped by indication on this page.
What phase is Tafasitamab in?
Tafasitamab clinical trials span 4 Phase 3, 24 Phase 2, 4 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Tafasitamab clinical trials?
The lead sponsor across the most Tafasitamab trials is Incyte Corporation, with 31 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Tafasitamabas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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Related pages on Hipa.ai:

Tafasitamab Clinical Trials (2026): 50 Studies | Hipa.ai