REGN7508 Clinical Trials (2026): 11 Studies for Atrial Fibrillation (AF) & Venous Thromboembolism
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
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11 REGN7508 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 8 indications (including Atrial Fibrillation (AF) & Venous Thromboembolism) and 18,276 total planned enrollment. 6 Phase 3 REGN7508 trials and 3 Phase 2 are listed. 7 REGN7508 clinical trials are actively recruiting at 92 U.S. sites across 22 states. Most recent activity: NCT07493304 (Jul 2031).
Where to Participate: All REGN7508 Trial Sites in the U.S. (92 sites across 22 states)
Every actively recruiting REGN7508trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AL | SEC Clinical Research | Dothan36305 | NCT07175428 | Map |
| AL | SEC Clinical Research | Dothan36305 | NCT07430956 | Map |
| AL | Eastern Shore Research Institute | Fairhope36532 | NCT07175428 | Map |
| AL | Shoals Medical Trials, Inc. | Sheffield35660 | NCT07015905 | Map |
| CA | Mission Cardiovascular Research Institute | Fremont94538 | NCT07175428 | Map |
| CA | Mission Cardiovascular Research Institute | Fremont94538 | NCT07430956 | Map |
| CA | National Institute of California Heart and Vein Specialists | Huntington Beach92648 | NCT07175428 | Map |
| CA | National Institute of California Heart and Vein Specialists | Huntington Beach92648 | NCT07430956 | Map |
| CA | Profound Research LLC at Southern California Heart Specialists | Pasadena91105 | NCT07175428 | Map |
| CA | Profound Research LLC at Southern California Heart Specialists | Pasadena91105 | NCT07430956 | Map |
| CA | Empire Clinical Research | Pomona91767 | NCT07175428 | Map |
| CA | Eisenhower Medical Center | Rancho Mirage92270 | NCT07213778 | Map |
| CA | CARI Clinical Trials | Riverside92504 | NCT07015905 | Map |
| CA | Northbay Clinical Research Center | Santa Rosa95405 | NCT07175428 | Map |
| CA | Cardiology Associates Medical Group | Ventura93003 | NCT07175428 | Map |
| CA | Cardiology Associates Medical Group | Ventura93003 | NCT07430956 | Map |
| CA | Interventional Cardiology Medical Group | West Hills91307 | NCT07175428 | Map |
| CA | Interventional Cardiology Medical Group | West Hills91307 | NCT07430956 | Map |
| CO | Denver Metro Orthopedics, P.C. Englewood Location | Englewood80113 | NCT07015905 | Map |
| CO | Sky Ridge Medical Center | Lone Tree80124 | NCT07213778 | Map |
| FL | Nouvelle Clinical Research LLC | Cutler Bay33189 | NCT07175428 | Map |
| FL | Delray Physician Care Center | Delray Beach33445 | NCT07015905 | Map |
| FL | Bioresearch Partner- Hialeah Hospital | Hialeah33013 | NCT07410117 | Map |
| FL | Bioresearch Partner- Hialeah Hospital | Hialeah33013 | NCT07493304 | Map |
| FL | South Florida Research Organization LLC | Medley33166 | NCT07430956 | Map |
| FL | Bioresearch Partner | Miami33175 | NCT07015905 | Map |
| FL | Medical Research of Westchester - MPLUS Research Network | Miami33165 | NCT07213778 | Map |
| FL | Inpatient Research Clinic LLC | Miami Lakes33014 | NCT07175428 | Map |
| FL | Helios Clinical Research | North Miami Beach33169 | NCT07410117 | Map |
| FL | Sacred Heart Health System Inc | Pensacola32504 | NCT07015905 | Map |
| FL | Cardiovascular Center of Sarasota Foundation for Research and Education | Sarasota34239 | NCT07175428 | Map |
| FL | Gulfcoast Research Institute | Sarasota34232 | NCT07015905 | Map |
| FL | Phoenix Clinical Research | Tamarac33321 | NCT07015905 | Map |
| FL | Phoenix Clinical Research | Tamarac33321 | NCT07213778 | Map |
| FL | Clinical Site Partners, LLC DBA Flourish Research | Winter Park32789 | NCT07175428 | Map |
| FL | Clinical Site Partners, LLC DBA Flourish Research | Winter Park32789 | NCT07430956 | Map |
| GA | Health Sciences Research Building II | Atlanta30322 | NCT07175428 | Map |
| GA | NSC Research, Inc | Johns Creek30024 | NCT07175428 | Map |
| GA | NSC Research, Inc | Johns Creek30024 | NCT07430956 | Map |
| IL | Endeavor Health | Skokie60076 | NCT07213778 | Map |
| IN | Blue Coast Research Center, LLC | Indianapolis46237 | NCT07175428 | Map |
| IN | Franciscan Physician Network, Indiana Heart Physicians | Indianapolis46237 | NCT07175428 | Map |
| IN | Indiana University | Indianapolis46202 | NCT07175428 | Map |
| IN | The Orthopaedic Research Foundation, Inc. | Indianapolis46278 | NCT07213778 | Map |
| IN | Indiana Medical Research | Merrillville46410 | NCT07175428 | Map |
| IN | Reid Physician Associates | Richmond47374 | NCT07175428 | Map |
| KS | NextStage Clinical Research, St. Francis Medical Park | Wichita67214 | NCT07213778 | Map |
| LA | Monroe Research, LLC | West Monroe71291 | NCT07175428 | Map |
| LA | Monroe Research, LLC | West Monroe71291 | NCT07430956 | Map |
| MD | Sinai Hospital of Baltimore, Inc. | Baltimore21215 | NCT07015905 | Map |
| MD | Sinai Hospital of Baltimore, Inc. | Baltimore21215 | NCT07213778 | Map |
| MD | Anderson Medical Research | Ft. Washington20744 | NCT07175428 | Map |
| MA | Beth Israel Lahey Health, Beth Israel Deaconess Medical Center (BIDMC) | Boston02215 | NCT07175428 | Map |
| MA | Brigham and Women's Hospital | Boston02115 | NCT07015905 | Map |
| MI | Profound Research, Millennium Cardiology | Farmington Hills48334 | NCT07175428 | Map |
| MI | AA Medical Research Center (MRC) | Flint48504 | NCT07175428 | Map |
| MI | AA Medical Research Center (MRC) | Flint48504 | NCT07430956 | Map |
| NJ | Holy Name Medical Center | Teaneck07666 | NCT07213778 | Map |
| NJ | Curalta Clinical Trials | Westwood07675 | NCT07015905 | Map |
| NC | Duke University Health System (Duke Health), Duke University Hospital | Durham27710 | NCT07015905 | Map |
| NC | Moses Cone Hospital Operating Corporation dba Cone Health, Lebauer-Brodie Center for Cardiovascular Research | Greensboro27401 | NCT07175428 | Map |
| NC | Eximia Equihealth Research-Raleigh. LLC | Raleigh27612 | NCT07213778 | Map |
| NC | The Vein and Vascular Center at Raleigh Radiology | Raleigh27612 | NCT07213778 | Map |
| NC | Coastal Vascular Institute, PA | Wilmington28401 | NCT07213778 | Map |
| OH | University of Cincinnati | Cincinnati45267 | NCT07213778 | Map |
| OH | Ohio Clinical Trials | Columbus43212 | NCT07213778 | Map |
| OH | The Ohio State University Wexner Medical Center | Columbus43210 | NCT07213778 | Map |
| OH | K&R Research LLC | Marion43302 | NCT07175428 | Map |
| OH | K&R Research LLC | Marion43302 | NCT07430956 | Map |
| OH | Advanced Medical Research | Maumee43537 | NCT07175428 | Map |
| PA | Keystone Clinical Studies LLC, dba Flourish Research | Plymouth Meeting19462 | NCT07015905 | Map |
| SD | Monument Health Clinical Research | Rapid City57701 | NCT07175428 | Map |
| TN | East Coast Institute for Research, Jefferson City | Jefferson City37760 | NCT07175428 | Map |
| TX | PharmaTex Research | Amarillo79106 | NCT07175428 | Map |
| TX | PharmaTex Research | Amarillo79106 | NCT07318610 | Map |
| TX | PharmaTex Research | Amarillo79106 | NCT07430956 | Map |
| TX | HD Research - First Surgical Hospital | Bellaire77401 | NCT07015905 | Map |
| TX | University of Texas (UT); Southwestern Medical Center | Dallas75390 | NCT07015905 | Map |
| TX | El Paso Medical Research Institute (Medresearch Inc) | El Paso79902 | NCT07410117 | Map |
| TX | El Paso Medical Research Institute (Medresearch Inc) | El Paso79902 | NCT07493304 | Map |
| TX | HD Research - Memorial Hermann Village | Houston77043 | NCT07213778 | Map |
| TX | NextStage Clinical Research, All American Orthopedics and Sports Medicine | Houston77058 | NCT07015905 | Map |
| TX | Futuro Clinical Trials | McAllen78501 | NCT07015905 | Map |
| TX | Complete Heart Care P.A. | McKinney75071 | NCT07175428 | Map |
| TX | Permian Research Foundation | Odessa79761 | NCT07175428 | Map |
| TX | Endeavor Clinical Trials | San Antonio78240 | NCT07213778 | Map |
| TX | Flourish Research - San Antonio (Formerly Clinical Trials of Texas) | San Antonio78229 | NCT07015905 | Map |
| TX | Tyler Cardiovascular Consultants | Tyler75701 | NCT07175428 | Map |
| UT | Alpine Research TC | Clinton84015 | NCT07175428 | Map |
| UT | DRx Clinical Research, LLC | St. George84770 | NCT07015905 | Map |
| VA | Carilion Clinic | Roanoke24015 | NCT07213778 | Map |
| WA | Spokane Joint Replacement Center | Spokane99218 | NCT07213778 | Map |
REGN7508 clinical trials at a glance: phase × recruitment status
| Phase | recruiting | completed | Total |
|---|---|---|---|
| P1 | 2 | 2 | |
| P2 | 1 | 2 | 3 |
| P3 | 6 | 6 |
Recruiting REGN7508 clinical trials (7)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07493304 | ROXI-CAT-IITreatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers | P3 | Venous Thromboembolism (VTE) | 1,600 | Jun 2026 |
| NCT07410117 | ROXI-CAT-IREGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis | P3 | Cancer-Associated Thrombosis (CAT) | 1,120 | Mar 2026 |
| NCT07318610 | ROXI-PALISADEReducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease | P3 | Peripheral Artery Disease (PAD) | 7,050 | May 2026 |
| NCT07430956 | ROXI-INCLINEStroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable | P3 | Atrial Fibrillation (AF) | 2,628 | Apr 2026 |
| NCT07213778 | ROXI-ASPENREGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants | P3 | Symptomatic Venous Thromboembolism (VTE) | 2,000 | Nov 2025 |
| NCT07015905 | ROXI-APEXREGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults | P3 | Venous Thromboembolism (VTE) | 2,000 | Jun 2025 |
| NCT07175428 | ROXI-ATLASSafety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation | P2 | Atrial Fibrillation (AF) | 1,200 | Oct 2025 |
REGN7508 clinical trials by indication
Venous Thromboembolism (VTE) (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07493304 | ROXI-CAT-II | P3 | recruiting | Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers |
| NCT07015905 | ROXI-APEX | P3 | recruiting | REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults |
Atrial Fibrillation (AF) (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07430956 | ROXI-INCLINE | P3 | recruiting | Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable |
| NCT07175428 | ROXI-ATLAS | P2 | recruiting | Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation |
Venous Thromboembolism (2)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06299111 | ROXI-CATH | P2 | completed | A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) |
| NCT06454630 | ROXI-VTE II | P2 | completed | A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants |
Peripheral Artery Disease (PAD) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07318610 | ROXI-PALISADE | P3 | recruiting | Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease |
Cancer-Associated Thrombosis (CAT) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07410117 | ROXI-CAT-I | P3 | recruiting | REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis |
Symptomatic Venous Thromboembolism (VTE) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07213778 | ROXI-ASPEN | P3 | recruiting | REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants |
Healthy Volunteers (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06444178 | — | P1 | completed | Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants |
Healthy Volunteer (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT05603195 | IV | P1 | completed | A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants |
REGN7508 pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| ROXI-CAT-II | NCT07493304 | P3 | recruiting | Venous Thromboembolism (VTE) | 1,600 | — |
| ROXI-CAT-I | NCT07410117 | P3 | recruiting | Cancer-Associated Thrombosis (CAT) | 1,120 | — |
| ROXI-PALISADE | NCT07318610 | P3 | recruiting | Peripheral Artery Disease (PAD) | 7,050 | — |
| ROXI-INCLINE | NCT07430956 | P3 | recruiting | Atrial Fibrillation (AF) | 2,628 | — |
| ROXI-ASPEN | NCT07213778 | P3 | recruiting | Symptomatic Venous Thromboembolism (VTE) | 2,000 | — |
| ROXI-APEX | NCT07015905 | P3 | recruiting | Venous Thromboembolism (VTE) | 2,000 | — |
| ROXI-ATLAS | NCT07175428 | P2 | recruiting | Atrial Fibrillation (AF) | 1,200 | — |
| ROXI-CATH | NCT06299111 | P2 | completed | Venous Thromboembolism | 195 | — |
| ROXI-VTE II | NCT06454630 | P2 | completed | Venous Thromboembolism | 179 | PMID 41218619 |
All REGN7508 trials (11)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07493304 | ROXI-CAT-II | Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers | P3 | recruiting | 1,600 | Regeneron Pharmaceuticals | Jun 2026 |
| NCT07410117 | ROXI-CAT-I | REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis | P3 | recruiting | 1,120 | Regeneron Pharmaceuticals | Mar 2026 |
| NCT07318610 | ROXI-PALISADE | Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease | P3 | recruiting | 7,050 | Regeneron Pharmaceuticals | May 2026 |
| NCT07430956 | ROXI-INCLINE | Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable | P3 | recruiting | 2,628 | Regeneron Pharmaceuticals | Apr 2026 |
| NCT07213778 | ROXI-ASPEN | REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants | P3 | recruiting | 2,000 | Regeneron Pharmaceuticals | Nov 2025 |
| NCT07015905 | ROXI-APEX | REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults | P3 | recruiting | 2,000 | Regeneron Pharmaceuticals | Jun 2025 |
| NCT07175428 | ROXI-ATLAS | Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation | P2 | recruiting | 1,200 | Regeneron Pharmaceuticals | Oct 2025 |
| NCT06299111 | ROXI-CATH | A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) | P2 | completed | 195 | Regeneron Pharmaceuticals | Sep 2024 |
| NCT06444178 | Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants | P1 | completed | 224 | Regeneron Pharmaceuticals | Sep 2024 | |
| NCT06454630 | ROXI-VTE II | A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants | P2 | completed | 179 | Regeneron Pharmaceuticals | Jun 2024 |
| NCT05603195 | IV | A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants | P1 | completed | 80 | Regeneron Pharmaceuticals | Jan 2023 |
REGN7508 clinical trials: frequently asked questions
- How many REGN7508 clinical trials are there?
- 11 REGN7508 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 7 are actively recruiting participants. 4 are marked completed.
- Are REGN7508 clinical trials recruiting in 2026?
- Yes — 7 REGN7508 trials are actively recruiting in 2026, with 92 U.S. sites across 22 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is REGN7508 being studied for?
- REGN7508 is being studied for Atrial Fibrillation (AF), Venous Thromboembolism, Venous Thromboembolism (VTE), Healthy Volunteers, Peripheral Artery Disease (PAD) and 3 more. The trials are grouped by indication on this page.
- What phase is REGN7508 in?
- REGN7508 clinical trials span 6 Phase 3, 3 Phase 2, 2 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors REGN7508 clinical trials?
- The lead sponsor across the most REGN7508 trials is Regeneron Pharmaceuticals. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming REGN7508as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
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