ponsegromab Clinical Trials (2026): 4 Studies for Cachexia & Colorectal Cancer

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

4 ponsegromab clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 4 indications (including Cachexia & Colorectal Cancer) and 1,642 total planned enrollment. 1 ponsegromab clinical trial is actively recruiting at 67 U.S. sites across 19 states. Most recent activity: NCT06989437 (Dec 2029).

Where to Participate: All ponsegromab Trial Sites in the U.S. (67 sites across 19 states)

Every actively recruiting ponsegromabtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALThe Kirklin Clinic of UAB HospitalBirmingham35233NCT06989437Map
ALThe University of Alabama at BirminghamBirmingham35294NCT06989437Map
ARCentral Arkansas Radiation Therapy Institute, dba CARTIBryant72022NCT06989437Map
ARCentral Arkansas Radiation Therapy Institute, dba CARTIConway72034NCT06989437Map
ARCARTI Cancer CenterLittle Rock72205NCT06989437Map
ARCentral Arkansas Radiation Therapy Institute, dba CARTINorth Little Rock72117NCT06989437Map
ARCentral Arkansas Radiation Therapy Institute, dba CARTIPine Bluff71603NCT06989437Map
CAUC San Diego Medical Center - EncinitasEncinitas92024NCT06989437Map
CAChao Family Comprehensive Cancer Center and Ambulatory CareIrvine92612NCT06989437Map
CAUCI Health - IrvineIrvine92612NCT06989437Map
CAUC San Diego Koman Family Outpatient PavilionLa Jolla92037NCT06989437Map
CAUC San Diego Medical Center - La Jolla (Jacobs Medical Center / Thornton Pavilion)La Jolla92037NCT06989437Map
CAUC San Diego Moores Cancer CenterLa Jolla92037NCT06989437Map
CAUC San Diego Sulpizio Cardiovascular CenterLa Jolla92037NCT06989437Map
CACedars-Sinai Cancer at Cedars-Sinai Medical CenterLos Angeles90048NCT06989437Map
CAUCLA Department of Medicine - Hematology/OncologyLos Angeles90095NCT06989437Map
CAUC Irvine HealthOrange92868NCT06989437Map
CAUC San Diego McGrath Outpatient Pavilion - HillcrestSan Diego92103NCT06989437Map
CAUC San Diego Medical Center - Bankers HillSan Diego92101NCT06989437Map
CAUC San Diego Medical Center - HillcrestSan Diego92103NCT06989437Map
CAUC San Diego Medical Center - Rancho BernardoSan Diego92127NCT06989437Map
CAUCLA Hematology/Oncology - Santa MonicaSanta Monica90404NCT06989437Map
CAProvidence Medical FoundationSanta Rosa95403NCT06989437Map
CAUC San Diego Medical Center - VistaVista92081NCT06989437Map
DCGeorgetown University Medical CenterWashington D.C.20007NCT06989437Map
DCGeorgetown University Medical Center - Department of Pharmacy, Oncology PharmacyWashington D.C.20007NCT06989437Map
GAUniversity Cancer & Blood Center, LLCAthens30607NCT06989437Map
HICardiology Associates, Inc‘Aiea96701NCT06989437Map
HIInvision, LLCHonolulu96813NCT06989437Map
HIUniversity of Hawaii Cancer CenterHonolulu96813NCT06989437Map
ILCancer Care Specialists of IllinoisDecatur62526NCT06989437Map
ILDecatur Memorial HospitalDecatur62526NCT06989437Map
ILHope and Healing Clinical Research LLCHinsdale60521NCT06989437Map
ILHope and Healing Clinical Research LLC New Lenox- Research DepartmentNew Lenox60451NCT06989437Map
ILCancer Care Specialists of Illinois - Cancer Care Center of O'FallonO'Fallon62269NCT06989437Map
KSUnited Imaging ConsultantsLenexa66215NCT06989437Map
KSMidAmerica Cancer Care- American Oncology PartnersMerriam66204NCT06989437Map
KYUniversity of Kentucky Healthcare - Markey Cancer CenterLexington40536NCT06989437Map
KYUniversity of Kentucky Medical CenterLexington40536NCT06989437Map
KYUniversity of Kentucky Research FoundationLexington40506NCT06989437Map
KYUniversity of Kentucky, Markey Cancer Center Clinical Research Office (UK MCC CRO)Lexington40536NCT06989437Map
MDJHU Oncology Central Kit ServicesBaltimore21205NCT06989437Map
MDJohns Hopkins HospitalBaltimore21287NCT06989437Map
MDOncology Investigational Drug Service (IDS)Baltimore21287NCT06989437Map
MDSidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore21287NCT06989437Map
MOMidAmerica Cancer Care - American Oncology PartnersKansas City64132NCT06989437Map
MOPremier ImagingKansas City64114NCT06989437Map
MOSt. Joseph Medical CenterKansas City64114NCT06989437Map
NENebraska MedicineOmaha68105NCT06989437Map
NENebraska Medicine - Village PointeOmaha68118NCT06989437Map
NEUniversity of Nebraska Medical CenterOmaha68198NCT06989437Map
NVRenown Health Medical OncologyReno89502NCT06989437Map
NVRenown Office of Clinical ResearchReno89502NCT06989437Map
NVRenown Regional Medical CenterReno89502NCT06989437Map
NJJack & Sheryl Morris Cancer CenterNew Brunswick08901NCT06989437Map
NJRutgers Cancer InstituteNew Brunswick08901NCT06989437Map
NJRwj University Hospital SomersetSomerville08876NCT06989437Map
NJRWJ University Hospital Somerset, Steeplechase Cancer CenterSomerville08876NCT06989437Map
NYUniversity of Rochester Medical CenterRochester14642NCT06989437Map
NCUNC Hospitals, The University of North Carolina at Chapel HillChapel Hill27514NCT06989437Map
NCUniversity of North Carolina Hospitals at HillsboroughHillsborough27278NCT06989437Map
OROHSU Center for Health & Healing 1Portland97239NCT06989437Map
OROregon Health and Science UniversityPortland97239NCT06989437Map
OROSHU Center for Health and Healing 2Portland97239NCT06989437Map
TXHouston Methodist HospitalHouston77030NCT06989437Map
TXBaylor Scott & White Vasicek Cancer Treatment CenterTemple76508NCT06989437Map
WAVirginia Mason Medical CenterSeattle98101NCT06989437Map

ponsegromab clinical trials at a glance: phase × recruitment status

PhaserecruitingcompletedterminatedTotal
P111
P2112
P2/P311

Recruiting ponsegromab clinical trials (1)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT06989437A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and FatigueP2/P3Cachexia982Oct 2025

ponsegromab clinical trials by indication

Cachexia (1)

NCTAcronymPhaseStatusTitle
NCT06989437P2/P3recruitingA Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Healthy (1)

NCTAcronymPhaseStatusTitle
NCT05685264P1completedA Study to Learn How the Study Medicine (Ponsegromab) is Changed and Eliminated From Healthy Chinese Adults

Non-small Cell Lung Cancer (1)

NCTAcronymPhaseStatusTitle
NCT05546476PROACC-1P2completedStudy of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15

Heart Failure (1)

NCTAcronymPhaseStatusTitle
NCT05492500GARDEN TIMI 74P2terminatedA Study of Ponsegromab in People With Heart Failure

ponsegromab pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
PROACC-1NCT05546476P2completedNon-small Cell Lung Cancer187PMID 38500292
GARDEN TIMI 74NCT05492500P2terminatedHeart Failure455

Terminated and withdrawn ponsegromab trials (1)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

All ponsegromab trials (4)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT06989437A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and FatigueP2/P3recruiting982PfizerOct 2025
NCT05546476PROACC-1Study of the Efficacy and Safety of Ponsegromab in Patients With Cancer, Cachexia and Elevated GDF-15P2completed187PfizerNov 2022
NCT05492500GARDEN TIMI 74A Study of Ponsegromab in People With Heart FailureP2terminated455PfizerSep 2022
NCT05685264A Study to Learn How the Study Medicine (Ponsegromab) is Changed and Eliminated From Healthy Chinese AdultsP1completed18PfizerJan 2023

ponsegromab clinical trials: frequently asked questions

How many ponsegromab clinical trials are there?
4 ponsegromab clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 2 are marked completed.
Are ponsegromab clinical trials recruiting in 2026?
Yes — 1 ponsegromab trial is actively recruiting in 2026, with 67 U.S. sites across 19 states. See the recruiting trials and the per-state site list further down this page.
What conditions is ponsegromab being studied for?
ponsegromab is being studied for Cachexia, Colorectal Cancer, Fatigue, Healthy, Heart Failure and 4 more. The trials are grouped by indication on this page.
What phase is ponsegromab in?
ponsegromab clinical trials span 2 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors ponsegromab clinical trials?
The lead sponsor across the most ponsegromab trials is Pfizer. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming ponsegromabas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed .

Related pages on Hipa.ai:

ponsegromab Clinical Trials (2026): 4 Studies | Hipa.ai