ponsegromab Evidence: Trial Results and Peer-Reviewed Publications

Hipa.ai Research · Source: PubMed & ClinicalTrials.gov / AACT · Last updated: May 7, 2026

The clinical evidence base for ponsegromab comprises 2 peer-reviewed publications across 2 journals, 0 pivotal-trial primary-outcome rows reported to ClinicalTrials.gov, spanning indications including Anorexia. Most recent publication: Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design., J Cachexia Sarcopenia Muscle, 2024.

Top peer-reviewed publications

Curated set of pivotal-trial result papers and recent publications in high-tier journals.

Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design.
Groarke JD, Crawford J, Collins SM, et al. · J Cachexia Sarcopenia Muscle · 2024
PubMed: PMID 38500292 · NCT05546476 (PROACC-1) · Anorexia
Ponsegromab for the Treatment of Cancer Cachexia.
Groarke JD, Crawford J, Collins SM, et al. · N Engl J Med · 2024
PubMed: PMID 39282907 · NCT05546476 (PROACC-1) · Anorexia

Publications by year

2024–2024: 2 publications.

2024

Publications by indication

Anorexia (2)

Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design.
J Cachexia Sarcopenia Muscle · 2024 · PMID 38500292 · NCT05546476
Ponsegromab for the Treatment of Cancer Cachexia.
N Engl J Med · 2024 · PMID 39282907 · NCT05546476

Publications by journal

J Cachexia Sarcopenia Muscle1 paper
N Engl J Med1 paper

All ponsegromab publications (2)

2024 (2 papers)

Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design.
Groarke JD, Crawford J, Collins SM, et al. · J Cachexia Sarcopenia Muscle · 2024 · Derived
PubMed: PMID 38500292 · NCT05546476 (PROACC-1) · Anorexia
Ponsegromab for the Treatment of Cancer Cachexia.
Groarke JD, Crawford J, Collins SM, et al. · N Engl J Med · 2024 · Derived
PubMed: PMID 39282907 · NCT05546476 (PROACC-1) · Anorexia

Sources and methodology

Publications: ctgov.study_references (PubMed PMIDs auto-attached by ClinicalTrials.gov to each trial), reference types RESULT, DERIVED, and BACKGROUND.
Per-arm outcome values: ctgov.outcome_measurements joined to ctgov.design_outcomes where outcome_type = 'PRIMARY', restricted to phase PHASE3 and PHASE2/PHASE3.
Publication metadata (title, journal, year, authors): PubMed E-utilities efetch.fcgi
Data freshness: Thu, 07 May 2026 20:23:15 GMT.

This page summarizes published evidence for general reference and does not constitute medical advice. For clinical decisions, consult the linked primary publications and your healthcare provider. Data sourced from PubMed and the ClinicalTrials.gov / AACT database maintained by the Clinical Trials Transformation Initiative (CTTI).