Monalizumab Clinical Trials (2026): 21 Studies for Non-small Cell Lung Cancer & Adenocarcinoma of the Esophagus

Where to Participate: All Monalizumab Trial Sites in the U.S. (173 sites across 35 states)

Every actively recruiting Monalizumabtrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

Monalizumab clinical trials at a glance: phase × recruitment status

Recruiting Monalizumab clinical trials (6)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

Monalizumab clinical trials by indication

Monalizumab pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Terminated and withdrawn Monalizumab trials (4)

Studies that ended before completion. Reasons are filed in each trial's ClinicalTrials.gov entry.

• NCT06152523withdrawnMonalizumab and MEDI5752 in Patients With MSI and/or dMMR Metastatic Cancer
• NCT04145193withdrawnNovel Oncology Therapies in Combination With Adjuvant Chemo in High-risk MSS-CRC
• NCT02557516terminatedCombination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL
• NCT03307941withdrawnAssessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced Esoph and Gastro-esoph Jction CA

All Monalizumab trials (21)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

Monalizumab clinical trials: frequently asked questions

How many Monalizumab clinical trials are there?

21 Monalizumab clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 5 are actively recruiting participants. 6 are marked completed.

Are Monalizumab clinical trials recruiting in 2026?

Yes — 5 Monalizumab trials are actively recruiting in 2026, with 173 U.S. sites across 35 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Monalizumab being studied for?

Monalizumab is being studied for Non-small Cell Lung Cancer, Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Advanced or Metastatic Hematological or Solid Tumor, Advanced Solid Tumors and 35 more. The trials are grouped by indication on this page.

What phase is Monalizumab in?

Monalizumab clinical trials span 2 Phase 3, 13 Phase 2, 2 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Monalizumab clinical trials?

The lead sponsor across the most Monalizumab trials is MedImmune LLC, with 14 additional lead sponsors listed in the data. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Monalizumabas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 12, 2026.