How many Brenipatide clinical trials are there?

7 Brenipatide clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 7 are actively recruiting participants.

Are Brenipatide clinical trials recruiting in 2026?

Yes — 7 Brenipatide trials are actively recruiting in 2026, with 125 U.S. sites across 29 states. See the recruiting trials and the per-state site list further down this page.

What conditions is Brenipatide being studied for?

Brenipatide is being studied for Asthma, Bipolar Disorder, Depressive Disorder, Major, Obesity, Opioid Use Disorder and 3 more. The trials are grouped by indication on this page.

What phase is Brenipatide in?

Brenipatide clinical trials span 1 Phase 3, 5 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors Brenipatide clinical trials?

The lead sponsor across the most Brenipatide trials is Eli Lilly and Company. Each trial row links to the full study detail page including sponsor information.

Brenipatide Clinical Trials (2026): 7 Studies for Asthma & Bipolar Disorder

Creator: Hipa.ai Research
Published: 2026-04-22T18:34:10.765Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 18, 2026.

7 Brenipatide clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 7 indications (including Asthma & Bipolar Disorder) and 3,218 total planned enrollment. 1 Phase 3 Brenipatide trial and 5 Phase 2 are listed. 7 Brenipatide clinical trials are actively recruiting at 125 U.S. sites across 29 states. Most recent activity: NCT07219173 (Jun 2028).

Where to Participate: All Brenipatide Trial Sites in the U.S. (125 sites across 29 states)

Every actively recruiting Brenipatidetrial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AZ	NoesisPharma - Phoenix - East Shea Boulevard	Phoenix85028	NCT07420283	Map
AZ	AMR Clinical	Tempe85281	NCT07219173	Map
AR	Pillar Clinical Research- Little Rock	Little Rock72204	NCT07410507	Map
AR	Woodland International Research Group	Little Rock72211	NCT07420283	Map
AR	Woodland Research Northwest	Rogers72758	NCT07223840	Map
CA	Clinical Innovations, Inc. dba CITrials	Bellflower90706	NCT07410507	Map
CA	Ark Clinical Research - Fountain Valley	Fountain Valley92708	NCT07420283	Map
CA	Collaborative Neuroscience Research, LLC	Garden Grove92845	NCT07410507	Map
CA	NewportNativeMD, Inc.	Newport Beach92663	NCT07219173	Map
CA	California Medical Research Associates	Northridge91324	NCT07219173	Map
CA	ATP Clinical Research	Orange92866	NCT07286175	Map
CA	ATP Clinical Research	Orange92866	NCT07412756	Map
CA	Peninsula Research Associates	Rolling Hills Estates90274	NCT07219173	Map
CA	Center on Substance Use and Health (CSUH)	San Francisco94102	NCT07420283	Map
CA	UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission Bay	San Francisco94158	NCT07420283	Map
CA	Stanford University School of Medicine	Stanford94305	NCT07410507	Map
CA	Collaborative Neuroscience Research, LLC	Torrance90502	NCT07410507	Map
CA	Sunwise Clinical Research	Walnut Creek94596	NCT07410507	Map
CO	Asthma & Allergy Associates - Colorado Springs	Colorado Springs80907	NCT07219173	Map
CT	Institute of Living	Hartford06106	NCT07410507	Map
CT	Yale University School of Medicine	New Haven06519	NCT07286175	Map
FL	Bradenton Research Center, Inc.	Bradenton34205	NCT07420283	Map
FL	Magno Medical Research Group	Cooper City33024	NCT07410507	Map
FL	Fortrea Clinical Research Unit - Daytona Beach	Daytona Beach32117-5116	NCT07476118	Map
FL	K2 Medical Research - Daytona Beach	Daytona Beach32114	NCT07420283	Map
FL	AMR Clinical	Doral33172-2514	NCT07219173	Map
FL	AGA Clinical Trials	Hialeah33012	NCT07286175	Map
FL	NextPhase Research Florida - Hollywood	Hollywood33024	NCT07420283	Map
FL	TecTum Research	Hollywood33024	NCT07223840	Map
FL	Accel Research Sites - Lakeland Clinical Research Unit	Lakeland33803	NCT07420283	Map
FL	Innovative Clinical Research	Lauderhill33319	NCT07410507	Map
FL	Accel Research Sites - Maitland Clinical Research Unit	Maitland32751	NCT07286175	Map
FL	Accel Research Sites - Maitland Clinical Research Unit	Maitland32751	NCT07410507	Map
FL	K2 Medical Research - Maitland	Maitland32751	NCT07286175	Map
FL	K2 Medical Research ORLANDO	Maitland32751	NCT07223840	Map
FL	GTL Medical & Research Group	Miami33173	NCT07223840	Map
FL	Life Arc Research Centers - Miami	Miami33126	NCT07420283	Map
FL	Vital Medical Research	Miami33174	NCT07410507	Map
FL	Wellness Research Center	Miami33135	NCT07410507	Map
FL	Life Medical Research Group Corp	Miami Gardens33014	NCT07412756	Map
FL	Floridian Clinical Research, LLC	Miami Lakes33016-1518	NCT07286175	Map
FL	Advanced Research for Health Improvement, LLC	Naples34102	NCT07420283	Map
FL	CLA Research	Naples34116	NCT07286175	Map
FL	CLA Research	Naples34116	NCT07410507	Map
FL	Renstar Medical Research	Ocala34470	NCT07219173	Map
FL	Optimal Research Sites	Orange City32763	NCT07412756	Map
FL	Apg Research, Llc	Orlando32803	NCT07410507	Map
FL	Charter Research - Orlando	Orlando32803	NCT07286175	Map
FL	Charter Research - Orlando	Orlando32803	NCT07412756	Map
FL	Avanza Medical Research Center	Pensacola32503	NCT07219173	Map
FL	Innovative Research Institute - Port Charlotte	Port Charlotte33952	NCT07420283	Map
FL	Better Years Ahead Medical Center	Tampa33614	NCT07420283	Map
FL	USF Health	Tampa33613	NCT07219173	Map
FL	Neuroscience Research Institute - West Palm Beach	West Palm Beach33407	NCT07420283	Map
FL	Encore Medical Research - Weston	Weston33331	NCT07286175	Map
GA	Atlanta Center for Medical Research	Atlanta30331	NCT07286175	Map
GA	Atlanta Center for Medical Research	Atlanta30331	NCT07410507	Map
GA	Augusta University	Augusta30912	NCT07410507	Map
GA	CenExel iResearch, LLC	Decatur30030	NCT07412756	Map
GA	North Georgia Clinical Research	Woodstock30189	NCT07223840	Map
IL	Re:Cognition Health - Chicago	Chicago60611	NCT07410507	Map
IL	Axis Clinical Trials - Westchester	Westchester60154	NCT07219173	Map
IN	Indiana University Health Neuroscience Center	Indianapolis46202	NCT07412756	Map
IN	Indiana University Health Neuroscience Center	Indianapolis46202	NCT07420283	Map
IA	Covenant Medical Center	Waterloo50702	NCT07286175	Map
KY	University of Kentucky Chandler Medical Center	Lexington40508	NCT07420283	Map
KY	Allergy & Asthma Specialists, P.S.C.	Owensboro42301	NCT07219173	Map
MD	Maryland Treatment Centers - Mountain Manor Treatment Center	Baltimore21229	NCT07420283	Map
MD	Pharmasite Research, Inc.	Baltimore21208	NCT07412756	Map
MD	CBH Health	Gaithersburg20877	NCT07286175	Map
MA	McLean Hospital	Belmont02478	NCT07410507	Map
MA	Adams Clinical Boston	Boston02116	NCT07412756	Map
MA	Adams Clinical Boston	Boston02116	NCT07420283	Map
MA	Brigham and Women's Hospital	Boston02115	NCT07219173	Map
MA	Elixia MA	Springfield01103	NCT07286175	Map
MA	Adams Clinical Watertown	Watertown02472	NCT07286175	Map
MA	Adams Clinical Watertown	Watertown02472	NCT07410507	Map
MA	Adams Clinical Watertown	Watertown02472	NCT07412756	Map
MA	Adams Clinical Watertown	Watertown02472	NCT07420283	Map
MI	Revival Research Institute, LLC	Dearborn48126	NCT07223840	Map
MS	SKY Integrative Medical Center/SKYCRNG	Ridgeland39157	NCT07420283	Map
MO	Arch Clinical Trials	St Louis63141	NCT07223840	Map
MO	Arch Clinical Trials	St Louis63141	NCT07410507	Map
NV	AMR Clinical	Las Vegas89119	NCT07219173	Map
NV	Vector Clinical Trials	Las Vegas89128	NCT07223840	Map
NV	Vector Clinical Trials	Las Vegas89128	NCT07412756	Map
NY	Adams Clinical Harlem	New York10029	NCT07410507	Map
NY	Adams Clinical Harlem	New York10029	NCT07412756	Map
NY	Adams Clinical Harlem	New York10029	NCT07420283	Map
NY	Equity Medical	New York10455	NCT07219173	Map
NY	Rochester Clinical Research, LLC	Rochester14609	NCT07223840	Map
NY	Adams Clinical Bronx	The Bronx10461	NCT07420283	Map
OH	Ohio Clinical Trials	Columbus43212	NCT07420283	Map
OH	Insight Clinical Trials	Independence44131	NCT07410507	Map
OR	University of Oregon	Eugene97403	NCT07410507	Map
PA	Suburban Research Associates	Media19063	NCT07412756	Map
PA	Adams Clinical Philadelphia	Philadelphia19104	NCT07410507	Map
PA	Adams Clinical Philadelphia	Philadelphia19104	NCT07420283	Map
PA	Penn Medicine: University of Pennsylvania Health System	Philadelphia19104	NCT07286175	Map
PA	Allergy and Clinical Immunology Associates	Pittsburgh15241	NCT07219173	Map
RI	Brown University School of Public Health	Providence02903	NCT07420283	Map
SC	Coastal Carolina Research Center	North Charleston29405	NCT07223840	Map
SD	Avera Research Institute - Sioux Falls	Sioux Falls57108	NCT07420283	Map
SD	Circle Clinical Research	Sioux Falls57104	NCT07223840	Map
TX	Fortrea Clinical Research Unit	Dallas75247	NCT07476118	Map
TX	FutureSearch Trials of Dallas	Dallas75251	NCT07223840	Map
TX	Adams Clinical Dallas	DeSoto75115	NCT07410507	Map
TX	Adams Clinical Dallas	DeSoto75115	NCT07412756	Map
TX	Adams Clinical Dallas	DeSoto75115	NCT07420283	Map
TX	Re:Cognition Health - Fort Worth	Fort Worth76104	NCT07410507	Map
TX	Re:Cognition Health - Fort Worth	Fort Worth76104	NCT07412756	Map
TX	Biopharma Informatic, LLC	Houston77043	NCT07420283	Map
TX	The University of Texas Health Science Center at Houston	Houston77054	NCT07223840	Map
TX	Revival Research Institute, LLC	McKinney75071	NCT07286175	Map
TX	Pillar Clinical Research - Richardson	Richardson75080	NCT07286175	Map
UT	Alpine Research Organization	Clinton84015	NCT07286175	Map
UT	Alpine Research Organization	Clinton84015	NCT07412756	Map
VA	Re:Cognition Health	Fairfax22031	NCT07286175	Map
VA	Health Research of Hampton Roads, Inc.	Newport News23606	NCT07223840	Map
WA	Northwest Clinical Research Center	Bellevue98007	NCT07286175	Map
WA	Northwest Clinical Research Center	Bellevue98007	NCT07410507	Map
WA	Northwest Clinical Research Center	Bellevue98007	NCT07412756	Map
WA	Eastside Research Associates	Redmond98052	NCT07223840	Map
WA	University of Washington - Harborview Medical Center	Seattle98104	NCT07420283	Map
WI	Fortrea Clinical Research Unit Inc. - Madison	Madison53704	NCT07476118	Map

Brenipatide clinical trials at a glance: phase × recruitment status

Phase	recruiting	Total
P1	1	1
P2	5	5
P3	1	1

Recruiting Brenipatide clinical trials (7)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT07219173	A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma	P2	Asthma	531	Oct 2025
NCT07420283	RENEW-Op-1A Study of Brenipatide in Participants With Opioid Use Disorder	P2	Opioid Use Disorder	465	Feb 2026
NCT07412756	RENEW-MDD-1A Study of Brenipatide in Adult Participants With Major Depressive Disorder	P3	Depressive Disorder, Major	1,000	Feb 2026
NCT07410507	RENEW-Scz-1A Study of Brenipatide in Adult Participants With Schizophrenia	P2	Schizophrenia	450	Feb 2026
NCT07286175	A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)	P2	Bipolar Disorder	400	Nov 2025
NCT07476118	LY3537031A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity	P1	Obesity	150	Mar 2026
NCT07223840	RENEW-Smk-1A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse	P2	Smoking	222	Nov 2025

Brenipatide clinical trials by indication

Obesity (1)

NCT	Acronym	Phase	Status	Title
NCT07476118	LY3537031	P1	recruiting	A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity

Opioid Use Disorder (1)

NCT	Acronym	Phase	Status	Title
NCT07420283	RENEW-Op-1	P2	recruiting	A Study of Brenipatide in Participants With Opioid Use Disorder

Schizophrenia (1)

NCT	Acronym	Phase	Status	Title
NCT07410507	RENEW-Scz-1	P2	recruiting	A Study of Brenipatide in Adult Participants With Schizophrenia

Depressive Disorder, Major (1)

NCT	Acronym	Phase	Status	Title
NCT07412756	RENEW-MDD-1	P3	recruiting	A Study of Brenipatide in Adult Participants With Major Depressive Disorder

Bipolar Disorder (1)

NCT	Acronym	Phase	Status	Title
NCT07286175	—	P2	recruiting	A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

Smoking (1)

NCT	Acronym	Phase	Status	Title
NCT07223840	RENEW-Smk-1	P2	recruiting	A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

Asthma (1)

NCT	Acronym	Phase	Status	Title
NCT07219173	—	P2	recruiting	A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

Brenipatide pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
RENEW-MDD-1	NCT07412756	P3	recruiting	Depressive Disorder, Major	1,000	—
RENEW-Op-1	NCT07420283	P2	recruiting	Opioid Use Disorder	465	—
RENEW-Scz-1	NCT07410507	P2	recruiting	Schizophrenia	450	—
RENEW-Smk-1	NCT07223840	P2	recruiting	Smoking	222	—

All Brenipatide trials (7)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT07219173		A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma	P2	recruiting	531	Eli Lilly and Company	Oct 2025
NCT07420283	RENEW-Op-1	A Study of Brenipatide in Participants With Opioid Use Disorder	P2	recruiting	465	Eli Lilly and Company	Feb 2026
NCT07412756	RENEW-MDD-1	A Study of Brenipatide in Adult Participants With Major Depressive Disorder	P3	recruiting	1,000	Eli Lilly and Company	Feb 2026
NCT07410507	RENEW-Scz-1	A Study of Brenipatide in Adult Participants With Schizophrenia	P2	recruiting	450	Eli Lilly and Company	Feb 2026
NCT07286175		A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)	P2	recruiting	400	Eli Lilly and Company	Nov 2025
NCT07476118	LY3537031	A Study of Brenipatide (LY3537031) in Healthy Participants With Overweight or Obesity	P1	recruiting	150	Eli Lilly and Company	Mar 2026
NCT07223840	RENEW-Smk-1	A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse	P2	recruiting	222	Eli Lilly and Company	Nov 2025

Brenipatide clinical trials: frequently asked questions

How many Brenipatide clinical trials are there?: 7 Brenipatide clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 7 are actively recruiting participants.
Are Brenipatide clinical trials recruiting in 2026?: Yes — 7 Brenipatide trials are actively recruiting in 2026, with 125 U.S. sites across 29 states. See the recruiting trials and the per-state site list further down this page.
What conditions is Brenipatide being studied for?: Brenipatide is being studied for Asthma, Bipolar Disorder, Depressive Disorder, Major, Obesity, Opioid Use Disorder and 3 more. The trials are grouped by indication on this page.
What phase is Brenipatide in?: Brenipatide clinical trials span 1 Phase 3, 5 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors Brenipatide clinical trials?: The lead sponsor across the most Brenipatide trials is Eli Lilly and Company. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming Brenipatideas an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 18, 2026.

Related pages on Hipa.ai:

Brenipatide overview