How many AZD0780 clinical trials are there?

16 AZD0780 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 10 are marked completed.

Are AZD0780 clinical trials recruiting in 2026?

Yes — 1 AZD0780 trial is actively recruiting in 2026, with 250 U.S. sites across 37 states. See the recruiting trials and the per-state site list further down this page.

What conditions is AZD0780 being studied for?

AZD0780 is being studied for Dyslipidemia, Dyslipidaemia, Healthy Participants, Cardiovascular Disease, Atherosclerotic Cardiovascular Disease and 4 more. The trials are grouped by indication on this page.

What phase is AZD0780 in?

AZD0780 clinical trials span 3 Phase 3, 3 Phase 2, 9 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.

Who sponsors AZD0780 clinical trials?

The lead sponsor across the most AZD0780 trials is AstraZeneca. Each trial row links to the full study detail page including sponsor information.

AZD0780 Clinical Trials (2026): 16 Studies for Dyslipidemia & Dyslipidaemia

Creator: Hipa.ai Research
Published: 2026-05-12T16:52:18.124Z

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: June 12, 2026.

16 AZD0780 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 9 indications (including Dyslipidemia & Dyslipidaemia) and 20,261 total planned enrollment. 3 Phase 3 AZD0780 trials and 3 Phase 2 are listed. 1 AZD0780 clinical trial is actively recruiting at 250 U.S. sites across 37 states. Most recent activity: NCT07000357 (Oct 2029).

Where to Participate: All AZD0780 Trial Sites in the U.S. (250 sites across 37 states)

Every actively recruiting AZD0780trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

State	Facility	City	Trial	Map
AL	Research Site	Birmingham35205	NCT07000357	Map
AL	Research Site	Fairhope36532	NCT07000357	Map
AL	Research Site	Foley36535	NCT07000357	Map
AL	Research Site	Mobile36608	NCT07000357	Map
AL	Research Site	Saraland36571	NCT07000357	Map
AL	Research Site	Vestavia Hills35216	NCT07000357	Map
AZ	Research Site	Gilbert85296	NCT07000357	Map
AZ	Research Site	Glendale85308	NCT07000357	Map
AZ	Research Site	Peoria85382	NCT07000357	Map
AZ	Research Site	Phoenix85014	NCT07000357	Map
AZ	Research Site	Phoenix85051	NCT07000357	Map
AZ	Research Site	Phoenix85053	NCT07000357	Map
AZ	Research Site	Scottsdale85260	NCT07000357	Map
AZ	Research Site	Tempe85283	NCT07000357	Map
AZ	Research Site	Tucson85715	NCT07000357	Map
AZ	Research Site	Tucson85745	NCT07000357	Map
CA	Research Site	Beverly Hills90211	NCT07000357	Map
CA	Research Site	Canoga Park91303	NCT07000357	Map
CA	Research Site	Castroville95012	NCT07000357	Map
CA	Research Site	Chula Vista91911	NCT07000357	Map
CA	Research Site	Fountain Valley92708	NCT07000357	Map
CA	Research Site	Garden Grove92844	NCT07000357	Map
CA	Research Site	Lancaster93534	NCT07000357	Map
CA	Research Site	Loma Linda92350	NCT07000357	Map
CA	Research Site	Loma Linda92357	NCT07000357	Map
CA	Research Site	Los Angeles90017	NCT07000357	Map
CA	Research Site	Los Angeles90035	NCT07000357	Map
CA	Research Site	Lynwood90262	NCT07000357	Map
CA	Research Site	Monterey Park91754	NCT07000357	Map
CA	Research Site	Newport Beach92663	NCT07000357	Map
CA	Research Site	Norco92860	NCT07000357	Map
CA	Research Site	Northridge91325	NCT07000357	Map
CA	Research Site	Pomona91768	NCT07000357	Map
CA	Research Site	Riverside92503	NCT07000357	Map
CA	Research Site	San Diego92111	NCT07000357	Map
CA	Research Site	San Dimas91773	NCT07000357	Map
CA	Research Site	Santa Ana92705	NCT07000357	Map
CA	Research Site	Tarzana91356	NCT07000357	Map
CA	Research Site	Thousand Oaks91360	NCT07000357	Map
CA	Research Site	Torrance90502	NCT07000357	Map
CA	Research Site	West Hills91307	NCT07000357	Map
CT	Research Site	Waterbury06708	NCT07000357	Map
FL	Research Site	Clearwater33756	NCT07000357	Map
FL	Research Site	Coral Gables33134	NCT07000357	Map
FL	Research Site	Crystal River34429	NCT07000357	Map
FL	Research Site	DeLand32720	NCT07000357	Map
FL	Research Site	Fleming Island32003	NCT07000357	Map
FL	Research Site	Fort Lauderdale33308	NCT07000357	Map
FL	Research Site	Hallandale33009	NCT07000357	Map
FL	Research Site	Hialeah33012	NCT07000357	Map
FL	Research Site	Hollywood33021	NCT07000357	Map
FL	Research Site	Homestead33030	NCT07000357	Map
FL	Research Site	Inverness34452	NCT07000357	Map
FL	Research Site	Jacksonville32204	NCT07000357	Map
FL	Research Site	Jacksonville32205	NCT07000357	Map
FL	Research Site	Jacksonville32216	NCT07000357	Map
FL	Research Site	Lake City32055	NCT07000357	Map
FL	Research Site	Lake Worth33462	NCT07000357	Map
FL	Research Site	Lakeland33805	NCT07000357	Map
FL	Research Site	Lakeland33813	NCT07000357	Map
FL	Research Site	Largo33777	NCT07000357	Map
FL	Research Site	Longwood32750	NCT07000357	Map
FL	Research Site	Maitland32751	NCT07000357	Map
FL	Research Site	Margate33063	NCT07000357	Map
FL	Research Site	Miami33176	NCT07000357	Map
FL	Research Site	Miami33186	NCT07000357	Map
FL	Research Site	Miami33269	NCT07000357	Map
FL	Research Site	Miami Lakes33014	NCT07000357	Map
FL	Research Site	Miami Lakes33016	NCT07000357	Map
FL	Research Site	Naples34102	NCT07000357	Map
FL	Research Site	New Port Richey34652	NCT07000357	Map
FL	Research Site	New Port Richey34653	NCT07000357	Map
FL	Research Site	Ocala34470	NCT07000357	Map
FL	Research Site	Orlando32801	NCT07000357	Map
FL	Research Site	Orlando32807	NCT07000357	Map
FL	Research Site	Orlando32825	NCT07000357	Map
FL	Research Site	Palm Harbor34684	NCT07000357	Map
FL	Research Site	Palmetto Bay33157	NCT07000357	Map
FL	Research Site	Pembroke Pines33029	NCT07000357	Map
FL	Research Site	Port Charlotte33952	NCT07000357	Map
FL	Research Site	Safety Harbor34695	NCT07000357	Map
FL	Research Site	Saint Augustine32086	NCT07000357	Map
FL	Research Site	Seminole33777	NCT07000357	Map
FL	Research Site	Tampa33625	NCT07000357	Map
FL	Research Site	West Palm Beach33401	NCT07000357	Map
GA	Research Site	Atlanta30328	NCT07000357	Map
GA	Research Site	Atlanta30342	NCT07000357	Map
GA	Research Site	Canton30114	NCT07000357	Map
GA	Research Site	Decatur30030	NCT07000357	Map
GA	Research Site	Decatur30033	NCT07000357	Map
GA	Research Site	Hinesville31313	NCT07000357	Map
GA	Research Site	Macon31210	NCT07000357	Map
GA	Research Site	Peachtree Corners30092	NCT07000357	Map
GA	Research Site	Riverdale30274	NCT07000357	Map
GA	Research Site	Stockbridge30281	NCT07000357	Map
GA	Research Site	Tucker30084	NCT07000357	Map
GA	Research Site	Union City30291	NCT07000357	Map
IL	Research Site	Chicago60607	NCT07000357	Map
IL	Research Site	Gurnee60031	NCT07000357	Map
IL	Research Site	Melrose Park60160	NCT07000357	Map
IL	Research Site	Tinley Park60477	NCT07000357	Map
IL	Research Site	Winfield60190	NCT07000357	Map
IN	Research Site	Carmel46290	NCT07000357	Map
IN	Research Site	Evansville47714	NCT07000357	Map
IN	Research Site	Evansville47715	NCT07000357	Map
IN	Research Site	Munster46321	NCT07000357	Map
IA	Research Site	Ames50010	NCT07000357	Map
IA	Research Site	Waterloo50701	NCT07000357	Map
IA	Research Site	West Des Moines50266	NCT07000357	Map
KS	Research Site	Kansas City66112	NCT07000357	Map
KS	Research Site	Kansas City66160	NCT07000357	Map
KS	Research Site	Wichita67218	NCT07000357	Map
KY	Research Site	Bowling Green42101	NCT07000357	Map
KY	Research Site	Lexington40503	NCT07000357	Map
KY	Research Site	Owensboro42301	NCT07000357	Map
KY	Research Site	Paducah42001	NCT07000357	Map
KY	Research Site	Versailles40383	NCT07000357	Map
LA	Research Site	Bossier City71111	NCT07000357	Map
LA	Research Site	Covington70433	NCT07000357	Map
LA	Research Site	Hammond70403	NCT07000357	Map
LA	Research Site	Lake Charles70601	NCT07000357	Map
LA	Research Site	Shreveport71105	NCT07000357	Map
LA	Research Site	Zachary70791	NCT07000357	Map
ME	Research Site	Bangor04401	NCT07000357	Map
ME	Research Site	Scarborough04074	NCT07000357	Map
MD	Research Site	Annapolis21401	NCT07000357	Map
MD	Research Site	Baltimore21229	NCT07000357	Map
MD	Research Site	Beltsville20705	NCT07000357	Map
MD	Research Site	Columbia21044	NCT07000357	Map
MD	Research Site	Lanham20706	NCT07000357	Map
MD	Research Site	Oxon Hill20745	NCT07000357	Map
MD	Research Site	Pikesville21208	NCT07000357	Map
MA	Research Site	Boston02111	NCT07000357	Map
MA	Research Site	Brookline02446	NCT07000357	Map
MI	Research Site	Dearborn Heights48127	NCT07000357	Map
MI	Research Site	Farmington Hills48336	NCT07000357	Map
MI	Research Site	Southfield48034	NCT07000357	Map
MI	Research Site	Southfield48076	NCT07000357	Map
MN	Research Site	Duluth55805	NCT07000357	Map
MN	Research Site	Minneapolis55423	NCT07000357	Map
MN	Research Site	Minneapolis55435	NCT07000357	Map
MN	Research Site	Saint Cloud56303	NCT07000357	Map
MO	Research Site	Bridgeton63044	NCT07000357	Map
MO	Research Site	Chesterfield63005	NCT07000357	Map
MO	Research Site	Hazelwood63042	NCT07000357	Map
MO	Research Site	Jefferson City65109	NCT07000357	Map
MO	Research Site	Kansas City64151	NCT07000357	Map
MO	Research Site	Springfield65807	NCT07000357	Map
MT	Research Site	Missoula59808	NCT07000357	Map
NE	Research Site	Elkhorn68022	NCT07000357	Map
NE	Research Site	Fremont68025	NCT07000357	Map
NE	Research Site	Omaha68144	NCT07000357	Map
NV	Research Site	Las Vegas89102	NCT07000357	Map
NV	Research Site	Las Vegas89119	NCT07000357	Map
NV	Research Site	Las Vegas89128	NCT07000357	Map
NJ	Research Site	Bridgewater08807	NCT07000357	Map
NJ	Research Site	Somerset08873	NCT07000357	Map
NY	Research Site	Brooklyn11201	NCT07000357	Map
NY	Research Site	Buffalo14217	NCT07000357	Map
NY	Research Site	Laurelton11413	NCT07000357	Map
NY	Research Site	New York10029	NCT07000357	Map
NY	Research Site	The Bronx10451	NCT07000357	Map
NC	Research Site	Chapel Hill27599	NCT07000357	Map
NC	Research Site	Durham27701	NCT07000357	Map
NC	Research Site	Monroe28112	NCT07000357	Map
NC	Research Site	Morehead City28557	NCT07000357	Map
NC	Research Site	Morganton28655	NCT07000357	Map
NC	Research Site	New Bern28562	NCT07000357	Map
NC	Research Site	Wilmington28401	NCT07000357	Map
NC	Research Site	Winston-Salem27157	NCT07000357	Map
ND	Research Site	Fargo58104	NCT07000357	Map
OH	Research Site	Cincinnati45220	NCT07000357	Map
OH	Research Site	Columbus43213	NCT07000357	Map
OH	Research Site	Lima45805	NCT07000357	Map
OH	Research Site	Maumee43537	NCT07000357	Map
OK	Research Site	Norman73069	NCT07000357	Map
PA	Research Site	Camp Hill17011	NCT07000357	Map
PA	Research Site	Duncansville16635	NCT07000357	Map
PA	Research Site	Horsham19044	NCT07000357	Map
PA	Research Site	Philadelphia19114	NCT07000357	Map
PA	Research Site	Smithfield15478	NCT07000357	Map
PA	Research Site	West Chester19380	NCT07000357	Map
PA	Research Site	Yardley19067	NCT07000357	Map
RI	Research Site	Providence02908	NCT07000357	Map
SC	Research Site	Charleston29402	NCT07000357	Map
SC	Research Site	Fort Mill29707	NCT07000357	Map
SC	Research Site	Mauldin29662	NCT07000357	Map
SC	Research Site	Myrtle Beach29572	NCT07000357	Map
SC	Research Site	North Charleston29405	NCT07000357	Map
SC	Research Site	North Charleston29406	NCT07000357	Map
SD	Research Site	Rapid City57701	NCT07000357	Map
TN	Research Site	Chattanooga37404	NCT07000357	Map
TN	Research Site	Chattanooga37421	NCT07000357	Map
TN	Research Site	Knoxville37849	NCT07000357	Map
TN	Research Site	Knoxville37912	NCT07000357	Map
TN	Research Site	Knoxville37938	NCT07000357	Map
TN	Research Site	Memphis38119	NCT07000357	Map
TN	Research Site	Memphis38128	NCT07000357	Map
TN	Research Site	Morristown37813	NCT07000357	Map
TN	Research Site	Tullahoma37388	NCT07000357	Map
TX	Research Site	Amarillo79106	NCT07000357	Map
TX	Research Site	Beaumont77706	NCT07000357	Map
TX	Research Site	Brownsville78526	NCT07000357	Map
TX	Research Site	Corpus Christi78404	NCT07000357	Map
TX	Research Site	Dallas75216	NCT07000357	Map
TX	Research Site	Dallas75234	NCT07000357	Map
TX	Research Site	Dallas75246	NCT07000357	Map
TX	Research Site	DeSoto75115	NCT07000357	Map
TX	Research Site	El Paso79902	NCT07000357	Map
TX	Research Site	El Paso79905	NCT07000357	Map
TX	Research Site	Euless76040	NCT07000357	Map
TX	Research Site	Houston77002	NCT07000357	Map
TX	Research Site	Houston77025	NCT07000357	Map
TX	Research Site	Houston77034	NCT07000357	Map
TX	Research Site	Houston77043	NCT07000357	Map
TX	Research Site	Houston77087	NCT07000357	Map
TX	Research Site	Humble77338	NCT07000357	Map
TX	Research Site	Irving75061	NCT07000357	Map
TX	Research Site	Katy77450	NCT07000357	Map
TX	Research Site	Kingwood77345	NCT07000357	Map
TX	Research Site	McAllen78503	NCT07000357	Map
TX	Research Site	McKinney75069	NCT07000357	Map
TX	Research Site	Mesquite75149	NCT07000357	Map
TX	Research Site	Paris75462	NCT07000357	Map
TX	Research Site	Pharr78577	NCT07000357	Map
TX	Research Site	Plano75093	NCT07000357	Map
TX	Research Site	San Antonio78207	NCT07000357	Map
TX	Research Site	San Antonio78212	NCT07000357	Map
TX	Research Site	Sugar Land77478	NCT07000357	Map
TX	Research Site	Sugar Land77479	NCT07000357	Map
TX	Research Site	Temple76508	NCT07000357	Map
TX	Research Site	Tomball77375	NCT07000357	Map
TX	Research Site	Tyler75701	NCT07000357	Map
TX	Research Site	Victoria77901	NCT07000357	Map
UT	Research Site	Bountiful84010	NCT07000357	Map
UT	Research Site	Ogden84405	NCT07000357	Map
UT	Research Site	Salt Lake City84148	NCT07000357	Map
VA	Research Site	Fairfax22031	NCT07000357	Map
VA	Research Site	Falls Church22042	NCT07000357	Map
VA	Research Site	Hopewell23860	NCT07000357	Map
VA	Research Site	Manassas20110	NCT07000357	Map
VA	Research Site	Newport News23606	NCT07000357	Map
VA	Research Site	Norfolk23504	NCT07000357	Map
VA	Research Site	Richmond23219	NCT07000357	Map
VA	Research Site	Suffolk23435	NCT07000357	Map
WA	Research Site	Redmond98052	NCT07000357	Map
WA	Research Site	Renton98057	NCT07000357	Map
WA	Research Site	Seattle98122	NCT07000357	Map
WA	Research Site	Tacoma98405	NCT07000357	Map
WV	Research Site	Morgantown26505	NCT07000357	Map

AZD0780 clinical trials at a glance: phase × recruitment status

Phase	recruiting	active not recruiting	completed	Total
P1		1	8	9
P2		1	2	3
P2/P3		1		1
P3	1	2		3

Recruiting AZD0780 clinical trials (1)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT ID	Title	Phase	Indication	Enrollment	Started
NCT07000357	AZURE-OutcomesA Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event	P3	Cardiovascular Disease	15,100	Jun 2025

AZD0780 clinical trials by indication

Dyslipidemia (4)

NCT	Acronym	Phase	Status	Title
NCT06742853	—	P1	completed	A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.
NCT06173570	PURSUIT	P2	completed	A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia
NCT05384262	—	P1	completed	A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
NCT05787002	—	P1	completed	A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Dyslipidaemia (3)

NCT	Acronym	Phase	Status	Title
NCT06834932	—	P2/P3	active not recruiting	A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia
NCT07218900	LAZURE	P2	active not recruiting	A Study to Investigate the Effect of AZD0780 Tablets in Combination With Rosuvastatin Tablets on Low Density Lipoprotein Cholesterol Levels (LDL-C) in Adult Participants With Dyslipidaemia
NCT06671405	—	P1	completed	An Open-label Study in Healthy Participants to Evaluate AZD0780 as an Object or Precipitant of CYP3A4-mediated Drug-drug Interactions

Healthy Participants (2)

NCT	Acronym	Phase	Status	Title
NCT07423598	—	P1	active not recruiting	A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels
NCT07216131	—	P1	completed	A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years

Cardiovascular Disease (2)

NCT	Acronym	Phase	Status	Title
NCT07000357	AZURE-Outcomes	P3	recruiting	A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
NCT07000123	AZURE-LDL	P3	active not recruiting	A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Heterozygous Familial Hypercholesterolaemia (1)

NCT	Acronym	Phase	Status	Title
NCT07000136	AZURE-HeFH	P3	active not recruiting	A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH

Atherosclerotic Cardiovascular Disease (1)

NCT	Acronym	Phase	Status	Title
NCT06692764	AZD0780-ABPM	P2	completed	A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure

Hepatic Impairment (1)

NCT	Acronym	Phase	Status	Title
NCT06576765	—	P1	completed	Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780

Renal Impairment (1)

NCT	Acronym	Phase	Status	Title
NCT06592482	—	P1	completed	A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780

Cardiovascular Diseases (1)

NCT	Acronym	Phase	Status	Title
NCT05817461	—	P1	completed	An ADME Study of [14C]AZD0780 in Healthy Male Subjects

AZD0780 pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

Acronym	NCT	Phase	Status	Indication	Enrollment	PubMed
AZURE-Outcomes	NCT07000357	P3	recruiting	Cardiovascular Disease	15,100	—
AZURE-LDL	NCT07000123	P3	active not recruiting	Cardiovascular Disease	3,103	—
AZURE-HeFH	NCT07000136	P3	active not recruiting	Heterozygous Familial Hypercholesterolaemia	473	—
LAZURE	NCT07218900	P2	active not recruiting	Dyslipidaemia	76	—
AZD0780-ABPM	NCT06692764	P2	completed	Atherosclerotic Cardiovascular Disease	202	—
PURSUIT	NCT06173570	P2	completed	Dyslipidemia	428	PMID 40167413

All AZD0780 trials (16)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT ID	Acronym	Title	Phase	Status	Enrollment	Sponsor	Started
NCT07000357	AZURE-Outcomes	A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event	P3	recruiting	15,100	AstraZeneca	Jun 2025
NCT06834932		A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 in Participants With Dyslipidaemia	P2/P3	active not recruiting	432	AstraZeneca	Dec 2024
NCT07000123	AZURE-LDL	A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event	P3	active not recruiting	3,103	AstraZeneca	May 2025
NCT07000136	AZURE-HeFH	A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH	P3	active not recruiting	473	AstraZeneca	Jun 2025
NCT07218900	LAZURE	A Study to Investigate the Effect of AZD0780 Tablets in Combination With Rosuvastatin Tablets on Low Density Lipoprotein Cholesterol Levels (LDL-C) in Adult Participants With Dyslipidaemia	P2	active not recruiting	76	AstraZeneca	Nov 2025
NCT07423598		A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels	P1	active not recruiting	40	AstraZeneca	Feb 2026
NCT07216131		A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years	P1	completed	14	AstraZeneca	Nov 2025
NCT06742853		A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.	P1	completed	81	AstraZeneca	Dec 2024
NCT06692764	AZD0780-ABPM	A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure	P2	completed	202	AstraZeneca	Oct 2024
NCT06671405		An Open-label Study in Healthy Participants to Evaluate AZD0780 as an Object or Precipitant of CYP3A4-mediated Drug-drug Interactions	P1	completed	59	AstraZeneca	Sep 2024
NCT06592482		A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780	P1	completed	30	AstraZeneca	Aug 2024
NCT06576765		Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780	P1	completed	16	AstraZeneca	Aug 2024
NCT06173570	PURSUIT	A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia	P2	completed	428	AstraZeneca	Jan 2024
NCT05384262		A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects	P1	completed	183	AstraZeneca	May 2022
NCT05817461		An ADME Study of [14C]AZD0780 in Healthy Male Subjects	P1	completed	8	AstraZeneca	Apr 2023
NCT05787002		A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.	P1	completed	16	AstraZeneca	Mar 2023

AZD0780 clinical trials: frequently asked questions

How many AZD0780 clinical trials are there?: 16 AZD0780 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants. 10 are marked completed.
Are AZD0780 clinical trials recruiting in 2026?: Yes — 1 AZD0780 trial is actively recruiting in 2026, with 250 U.S. sites across 37 states. See the recruiting trials and the per-state site list further down this page.
What conditions is AZD0780 being studied for?: AZD0780 is being studied for Dyslipidemia, Dyslipidaemia, Healthy Participants, Cardiovascular Disease, Atherosclerotic Cardiovascular Disease and 4 more. The trials are grouped by indication on this page.
What phase is AZD0780 in?: AZD0780 clinical trials span 3 Phase 3, 3 Phase 2, 9 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors AZD0780 clinical trials?: The lead sponsor across the most AZD0780 trials is AstraZeneca. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming AZD0780as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

Last refreshed June 12, 2026.

Related pages on Hipa.ai:

AZD0780 overview AZD0780 evidence & publications