Atezolizumab History and Updates

250 events · 2005 – present

Synced daily from openFDA and ClinicalTrials.gov. Last sync: .

109
FDA Approvals
2
Label Revisions
2,456
Trial Milestones
10
Pivotal Publications
Atezolizumab — history and updatesFDA approvals, label revisions, recalls, trials, and pivotal publicationsFDA approvalsLabel revisionsRecalls + safetyTrialsPublications20062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028202920302031203220332034203520362037203820392040Trial: NCT07170592 2027-01-31 → 2028-12-31 (primary completion)Trial: NCT07322341 2026-09-01 → 2030-11-01 (primary completion)Trial: NCT06492954 2026-07-31 → 2027-06-30 (primary completion)Trial: NCT07545954 2026-07-31 → 2029-08-31 (primary completion)Trial: NCT07059494 2026-06-30 → 2027-08-01 (primary completion)Trial: NCT07388524 2026-06-05 → 2029-09-30 (primary completion)Trial: NCT07339059 2026-06-01 → 2029-02-01 (primary completion)Trial: NCT07543510 2026-05-01 → 2028-08-31 (primary completion)Trial: NCT07472517 2026-04-13 → 2028-09-09 (primary completion)Trial: NCT07407933 2026-03-31 → 2028-11-30 (primary completion)Trial: NCT07461675 2026-03-25 → 2029-06-01 (primary completion)Trial: NCT07291076 2026-03-16 → 2029-10-15 (primary completion)Trial: NCT07190833 2026-03-09 → 2028-12-31 (primary completion)Trial: NCT07166406 2026-02-26 → 2029-03-10 (primary completion)Trial: NCT07227597 2026-01-29 → 2030-11-29 (primary completion)Trial: NCT07113691 2026-01-20 → 2030-01-31 (primary completion)Trial: NCT07235293 2026-01-16 → 2026-09-30 (primary completion)Trial: NCT07195695 2026-01-16 → 2032-02-26 (primary completion)Trial: NCT07281664 2026-01-01 → 2028-12-31 (primary completion)Trial: NCT07276100 2026-01-01 → 2027-01-01 (primary completion)Trial: NCT06680258 2025-12-31 → 2028-12-31 (primary completion)Trial: NCT07317414 2025-12-24 → 2028-12-05 (primary completion)Trial: NCT06908993 2025-12-09 → 2028-03-15 (primary completion)Trial: NCT07226999 2025-12-09 → 2030-06-14 (primary completion)Trial: NCT07018947 2025-11-30 → 2030-11-30 (primary completion)Trial: NCT07172412 2025-11-30 → 2027-12-31 (primary completion)Trial: NCT07155174 2025-11-25 → 2029-05-31 (primary completion)Trial: NCT07239245 2025-11-12 → 2027-11-10 (primary completion)Trial: NCT06066138 2025-11-04 → 2027-01-31 (primary completion)Trial: NCT07263438 2025-11-03 → 2028-03-30 (primary completion)Trial: NCT07285850 2025-10-20 → 2026-08-30 (primary completion)Trial: NCT07192185 2025-09-17 → 2026-12-01 (primary completion)Trial: NCT07049848 2025-09-11 → 2028-01-01 (primary completion)Trial: NCT07093762 2025-08-20 → 2028-06-30 (primary completion)Trial: NCT06603818 2025-08-15 → 2025-08-15 (primary completion)Trial: NCT06294548 2025-07-29 → 2028-01-30 (primary completion)Trial: NCT05690048 2025-07-16 → 2028-03-31 (primary completion)Trial: NCT07284121 2025-07-15 → 2027-03-31 (primary completion)Trial: NCT06823375 2025-07-10 → 2027-07-31 (primary completion)Trial: NCT07153445 2025-07-08 → 2035-05-02 (primary completion)Trial: NCT06939036 2025-07-01 → 2025-12-31 (primary completion)Trial: NCT05870800 2025-06-15 → 2026-09-01 (primary completion)Trial: NCT06971237 2025-06-01 → 2026-07-01 (primary completion)Trial: NCT06719973 2025-05-14 → 2025-05-14 (primary completion)Trial: NCT06830694 2025-05-13 → 2027-03-31 (primary completion)Trial: NCT06921785 2025-05-06 → 2029-03-16 (primary completion)Trial: NCT06762808 2025-05-01 → 2025-08-08 (primary completion)Trial: NCT06328036 2025-04-30 → 2025-07-01 (primary completion)Trial: NCT06760481 2025-04-13 → 2028-09-15 (primary completion)Trial: NCT06754501 2025-04-11 → 2027-07-01 (primary completion)Trial: NCT06731270 2025-04-09 → 2027-01-01 (primary completion)Trial: NCT06287775 2025-04-08 → 2029-07-25 (primary completion)Trial: NCT06784947 2025-03-25 → 2025-09-18 (primary completion)Trial: NCT06771622 2025-03-13 → 2028-01-01 (primary completion)Trial: NCT06690840 2025-03-06 → 2026-12-15 (primary completion)Trial: NCT06867432 2025-03-01 → 2026-03-01 (primary completion)Trial: NCT06789757 2025-02-25 → 2026-10-27 (primary completion)Trial: NCT06646276 2025-02-25 → 2028-04-06 (primary completion)Trial: NCT06717243 2025-02-20 → 2028-03-20 (primary completion)Trial: NCT07157969 2025-02-19 → 2026-06-01 (primary completion)Trial: NCT06712355 2025-02-03 → 2028-12-31 (primary completion)Trial: NCT06713798 2025-01-30 → 2025-09-15 (primary completion)Trial: NCT06807632 2025-01-29 → 2027-01-31 (primary completion)Trial: NCT06663098 2025-01-24 → 2028-08-30 (primary completion)Trial: NCT07538128 2025-01-09 → 2026-11-27 (primary completion)Trial: NCT06692491 2025-01-01 → 2027-12-31 (primary completion)Trial: NCT06616623 2024-12-31 → 2026-12-31 (primary completion)Trial: NCT05859217 2024-12-31 → 2026-06-30 (primary completion)Trial: NCT06584071 2024-12-31 → 2026-10-31 (primary completion)Trial: NCT06725121 2024-12-31 → 2031-06-30 (primary completion)Trial: NCT06488716 2024-12-16 → 2025-11-05 (primary completion)Trial: NCT06719336 2024-12-16 → 2028-12-16 (primary completion)Trial: NCT06632327 2024-12-11 → 2029-04-30 (primary completion)Trial: NCT06331598 2024-11-30 → 2028-10-20 (primary completion)Trial: NCT06439485 2024-11-19 → 2028-02-22 (primary completion)Trial: NCT06733038 2024-11-15 → 2028-04-01 (primary completion)Trial: NCT06618664 2024-10-28 → 2026-09-30 (primary completion)Trial: NCT06551142 2024-09-30 → 2028-10-16 (primary completion)Trial: NCT06463665 2024-09-26 → 2027-02-28 (primary completion)Trial: NCT06537310 2024-09-16 → 2027-05-12 (primary completion)Trial: NCT06444815 2024-09-16 → 2027-09-30 (primary completion)Trial: NCT06572722 2024-09-01 → 2026-09-01 (primary completion)Trial: NCT06780826 2024-08-28 → 2025-06-30 (primary completion)Trial: NCT06161532 2024-08-01 → 2027-11-01 (primary completion)Trial: NCT05733598 2024-08-01 → 2027-12-01 (primary completion)Trial: NCT06362252 2024-07-22 → 2026-09-30 (primary completion)Trial: NCT06503250 2024-07-19 → 2024-11-27 (primary completion)Trial: NCT06096779 2024-07-15 → 2027-07-30 (primary completion)Trial: NCT06416436 2024-07-15 → 2024-07-15 (primary completion)Trial: NCT06302426 2024-07-01 → 2026-10-30 (primary completion)Trial: NCT06478693 2024-07-01 → 2027-12-31 (primary completion)Trial: NCT06012734 2024-06-18 → 2026-07-31 (primary completion)Trial: NCT06342037 2024-06-12 → 2026-04-01 (primary completion)Trial: NCT06332755 2024-06-05 → 2027-11-30 (primary completion)Trial: NCT05703971 2024-05-09 → 2026-06-30 (primary completion)Trial: NCT06110572 2024-04-24 → 2027-06-30 (primary completion)Trial: NCT06099418 2024-04-18 → 2027-05-31 (primary completion)Trial: NCT06067061 2024-04-05 → 2025-05-07 (primary completion)Trial: NCT07293468 2024-04-01 → 2034-03-31 (primary completion)Trial: NCT06339424 2024-03-30 → 2029-03-30 (primary completion)Trial: NCT06267001 2024-03-21 → 2025-12-16 (primary completion)Trial: NCT06069726 2024-03-21 → 2028-01-01 (primary completion)Trial: NCT06077500 2024-02-14 → 2026-09-01 (primary completion)Trial: NCT06179069 2024-01-23 → 2027-05-30 (primary completion)Trial: NCT06043674 2024-01-22 → 2028-01-15 (primary completion)Trial: NCT06109272 2024-01-11 → 2030-09-30 (primary completion)Trial: NCT05999812 2023-12-19 → 2026-10-01 (primary completion)Trial: NCT06003621 2023-12-15 → 2026-05-01 (primary completion)Trial: NCT06496568 2023-12-11 → 2028-09-28 (primary completion)Trial: NCT06157827 2023-12-08 → 2026-12-28 (primary completion)Trial: NCT05798663 2023-12-07 → 2026-11-30 (primary completion)Trial: NCT05689671 2023-12-06 → 2026-03-05 (primary completion)Trial: NCT05836584 2023-12-06 → 2027-10-31 (primary completion)Trial: NCT05908786 2023-12-05 → 2025-08-27 (primary completion)Trial: NCT05833126 2023-12-03 → 2024-12-31 (primary completion)Trial: NCT05935774 2023-12-01 → 2028-07-31 (primary completion)Trial: NCT06031441 2023-11-27 → 2027-12-31 (primary completion)Trial: NCT06117891 2023-11-27 → 2026-11-27 (primary completion)Trial: NCT06133062 2023-11-16 → 2028-09-30 (primary completion)Trial: NCT06098898 2023-11-01 → 2024-11-01 (primary completion)Trial: NCT06254911 2023-10-27 → 2026-12-16 (primary completion)Trial: NCT05770102 2023-10-25 → 2029-10-31 (primary completion)Trial: NCT05542407 2023-10-23 → 2028-02-21 (primary completion)Trial: NCT05968326 2023-10-18 → 2031-01-01 (primary completion)Trial: NCT05483400 2023-10-18 → 2025-09-30 (primary completion)Trial: NCT05564416 2023-10-12 → 2024-01-01 (primary completion)Trial: NCT05867121 2023-10-02 → 2026-06-30 (primary completion)Trial: NCT05537402 2023-09-27 → 2025-06-06 (primary completion)Trial: NCT05715281 2023-09-26 → 2025-10-06 (primary completion)Trial: NCT05904886 2023-09-14 → 2025-05-08 (primary completion)Trial: NCT05652686 2023-09-05 → 2027-12-31 (primary completion)Trial: NCT06031233 2023-09-01 → 2028-07-31 (primary completion)Trial: NCT05984511 2023-08-30 → 2028-08-01 (primary completion)Trial: NCT06390059 2023-08-28 → 2025-11-18 (primary completion)Trial: NCT05746481 2023-08-10 → 2024-08-19 (primary completion)Trial: NCT06006286 2023-08-08 → 2023-11-10 (primary completion)Trial: NCT05510427 2023-08-07 → 2023-08-07 (primary completion)Trial: NCT04691817 2023-07-25 → 2026-12-31 (primary completion)Trial: NCT05944237 2023-07-13 → 2027-06-30 (primary completion)Trial: NCT06097962 2023-07-01 → 2026-07-01 (primary completion)Trial: NCT05733611 2023-06-29 → 2025-08-18 (primary completion)Trial: NCT05332561 2023-06-29 → 2030-03-31 (primary completion)Trial: NCT05834348 2023-06-23 → 2024-01-23 (primary completion)Trial: NCT05776875 2023-06-07 → 2024-12-05 (primary completion)Trial: NCT05681039 2023-06-02 → 2026-11-01 (primary completion)Trial: NCT05862285 2023-06-01 → 2033-03-01 (primary completion)Trial: NCT05825625 2023-05-26 → 2026-12-01 (primary completion)Trial: NCT05886465 2023-05-24 → 2024-06-01 (primary completion)Trial: NCT05907980 2023-05-24 → 2026-12-31 (primary completion)Trial: NCT06090318 2023-05-19 → 2023-05-30 (primary completion)Trial: NCT05750030 2023-05-16 → 2025-03-17 (primary completion)Trial: NCT05538091 2023-05-15 → 2031-03-17 (primary completion)Trial: NCT05501665 2023-05-09 → 2026-02-01 (primary completion)Trial: NCT05661578 2023-05-04 → 2025-12-26 (primary completion)Trial: NCT05781308 2023-04-26 → 2025-06-02 (primary completion)Trial: NCT05019703 2023-04-25 → 2027-12-31 (primary completion)Trial: NCT04796012 2023-04-18 → 2027-01-31 (primary completion)Trial: NCT05645692 2023-04-13 → 2026-12-31 (primary completion)Trial: NCT05459129 2023-04-12 → 2024-08-15 (primary completion)Trial: NCT05482516 2023-03-29 → 2026-12-31 (primary completion)Trial: NCT05411081 2023-03-24 → 2027-07-01 (primary completion)Trial: NCT05440708 2023-03-23 → 2027-02-01 (primary completion)Trial: NCT05717400 2023-03-17 → 2024-08-29 (primary completion)Trial: NCT05546879 2023-03-15 → 2026-03-19 (primary completion)Trial: NCT05063552 2023-03-13 → 2027-12-15 (primary completion)Trial: NCT05751343 2023-03-09 → 2024-08-28 (primary completion)Trial: NCT05665348 2023-03-09 → 2025-05-12 (primary completion)Trial: NCT05722886 2023-03-01 → 2029-10-31 (primary completion)Trial: NCT05516628 2023-02-28 → 2027-03-31 (primary completion)Trial: NCT05694013 2023-02-27 → 2024-06-30 (primary completion)Trial: NCT05300282 2023-02-27 → 2027-04-27 (primary completion)Trial: NCT05765084 2023-02-24 → 2027-10-31 (primary completion)Trial: NCT05394337 2023-02-23 → 2028-12-31 (primary completion)Trial: NCT04808245 2023-02-15 → 2026-11-30 (primary completion)Trial: NCT05515627 2023-02-15 → 2026-06-30 (primary completion)Trial: NCT05661188 2023-02-14 → 2027-06-30 (primary completion)Trial: NCT05295212 2023-02-01 → 2024-12-01 (primary completion)Trial: NCT05703997 2023-01-31 → 2025-01-31 (primary completion)Trial: NCT05185505 2023-01-30 → 2027-04-30 (primary completion)Trial: NCT05238831 2023-01-30 → 2026-05-31 (primary completion)Trial: NCT05448677 2022-12-15 → 2024-03-08 (primary completion)Trial: NCT05327738 2022-12-10 → 2027-12-04 (primary completion)Trial: NCT05211323 2022-12-07 → 2026-06-30 (primary completion)Trial: NCT05340309 2022-12-07 → 2026-12-31 (primary completion)Trial: NCT05259319 2022-12-05 → 2024-12-05 (primary completion)Trial: NCT05620771 2022-11-30 → 2026-07-01 (primary completion)Trial: NCT05468489 2022-11-18 → 2026-02-28 (primary completion)Trial: NCT05286801 2022-11-17 → 2030-03-31 (primary completion)Trial: NCT05060003 2022-11-08 → 2023-11-27 (primary completion)Trial: NCT05468359 2022-11-07 → 2032-06-30 (primary completion)Trial: NCT05377034 2022-10-26 → 2026-07-25 (primary completion)Trial: NCT05423210 2022-10-25 → 2027-08-31 (primary completion)Trial: NCT05992220 2022-10-22 → 2026-03-31 (primary completion)Trial: NCT05581004 2022-10-20 → 2028-07-31 (primary completion)Trial: NCT05595460 2022-10-10 → 2027-07-31 (primary completion)Trial: NCT05797493 2022-10-04 → 2027-06-30 (primary completion)Trial: NCT05525858 2022-09-28 → 2026-09-30 (primary completion)Trial: NCT05528952 2022-09-27 → 2028-03-27 (primary completion)Trial: NCT05039281 2022-09-23 → 2027-12-31 (primary completion)Trial: NCT05450562 2022-09-20 → 2025-12-22 (primary completion)FDA approval — 2005-12-02 FDA approved Hylenex Recombinant (hyaluronidase) (BLA 021859) Sponsor: HALOZYME THERAP. Class: Type 1 - New Molecular Entity.FDA approval (supplemental) — 2006-06-09 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-2) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2008-10-01 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-5) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2009-12-11 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-6) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2012-03-01 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-9) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2012-03-20 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-15) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2013-07-23 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-18) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2014-05-06 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-20) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2014-10-16 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-19) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2015-04-17 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-21) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2015-07-27 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-22) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2016-01-21 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-23) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval — 2016-05-18 FDA approved Tecentriq (atezolizumab) (BLA 761034) Sponsor: GENENTECH INC. Class: Type 1 - New Molecular Entity.FDA approval (supplemental) — 2016-06-21 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-25) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2016-07-28 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Manufacturing (CMC) (BLA 021859 S-24) Sponsor: HALOZYME THERAP. Class: Manufacturing (CMC).FDA approval (supplemental) — 2017-04-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-1) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2017-06-22 FDA approved supplemental application for Rituxan Hycela (rituximab and hyaluronidase) — Type 5 - New Formulation or New Manufacturer (BLA 761064 S-1) Sponsor: GENENTECH INC. Class: Type 5 - New Formulation or New Manufacturer.FDA approval — 2017-06-22 FDA approved Rituxan Hycela (rituximab and hyaluronidase) (BLA 761064) Sponsor: GENENTECH INC. Class: Type 5 - New Formulation or New Manufacturer.FDA approval (supplemental) — 2018-03-13 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-5) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2018-04-30 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-3) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2018-06-14 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-8) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2018-06-19 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-10) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2018-06-26 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-11) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2018-07-02 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-12) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2018-12-06 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-9) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval — 2019-02-28 FDA approved Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) (BLA 761106) Sponsor: GENENTECH INC. Class: Type 5 - New Formulation or New Manufacturer.FDA approval (supplemental) — 2019-03-08 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-18) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2019-03-18 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-19) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2019-05-06 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-13) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2019-05-06 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-14) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2019-12-03 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-21) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2019-12-19 FDA approved supplemental application for Rituxan Hycela (rituximab and hyaluronidase) — Labeling (BLA 761064 S-9) Sponsor: GENENTECH INC. Class: Labeling.FDA approval — 2020-05-01 FDA approved Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) (BLA 761145) Sponsor: JANSSEN BIOTECH. Class: Type 3 - New Dosage Form and Type 4 - New Combination.FDA approval (supplemental) — 2020-05-05 FDA approved supplemental application for Rituxan Hycela (rituximab and hyaluronidase) — Labeling (BLA 761064 S-10) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2020-05-05 FDA approved supplemental application for Rituxan Hycela (rituximab and hyaluronidase) — Labeling (BLA 761064 S-8) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2020-05-18 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-27) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2020-05-29 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-25) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval — 2020-06-29 FDA approved Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) (BLA 761170) Sponsor: GENENTECH INC. Class: Type 4 - New Combination.FDA approval (supplemental) — 2020-07-30 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-28) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2020-09-30 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-29) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2020-11-10 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-20) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2020-12-18 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-32) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2020-12-18 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-31) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-01-11 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-1) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2021-01-15 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-2) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2021-02-08 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-8) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-33) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-35) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-34) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-36) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-38) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-02-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-37) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-03-12 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-5) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval (supplemental) — 2021-04-13 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-41) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-06-10 FDA approved supplemental application for Rituxan Hycela (rituximab and hyaluronidase) — Labeling (BLA 761064 S-13) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2021-07-09 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-7) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2021-10-06 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-44) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-10-15 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-42) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2021-11-30 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-9) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2022-01-21 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-43) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2022-01-21 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-12) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval (supplemental) — 2022-11-02 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-18) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval (supplemental) — 2022-12-02 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-50) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2022-12-09 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-47) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2023-05-12 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-49) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2023-05-12 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-51) Sponsor: GENENTECH INC. Class: Labeling.FDA approval — 2023-06-20 FDA approved Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) (BLA 761304) Sponsor: ARGENX BV.FDA approval (supplemental) — 2023-12-12 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Labeling (BLA 761304 S-2) Sponsor: ARGENX BV. Class: Labeling.FDA approval (supplemental) — 2024-01-12 FDA approved supplemental application for Hylenex Recombinant (hyaluronidase) — Labeling (BLA 021859 S-31) Sponsor: HALOZYME THERAP. Class: Labeling.FDA approval (supplemental) — 2024-04-22 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-53) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2024-06-18 FDA approved supplemental application for Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) — Efficacy (BLA 761106 S-10) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2024-06-21 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Efficacy (BLA 761304 S-5) Sponsor: ARGENX BV. Class: Efficacy.FDA approval (supplemental) — 2024-06-21 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Labeling (BLA 761304 S-6) Sponsor: ARGENX BV. Class: Labeling.FDA approval (supplemental) — 2024-07-30 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-25) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2024-08-08 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Efficacy (BLA 761304 S-3) Sponsor: ARGENX BV. Class: Efficacy.FDA approval — 2024-09-12 FDA approved Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) (BLA 761347) Sponsor: GENENTECH INC. Class: Type 3 - New Dosage Form.FDA approval — 2024-09-13 FDA approved Ocrevus Zunovo (ocrelizumab and hyaluronidase) (BLA 761371) Sponsor: GENENTECH INC. Class: Type 3 - New Dosage Form.FDA approval (supplemental) — 2024-11-22 FDA approved supplemental application for Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) — Efficacy (BLA 761170 S-7) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval — 2024-12-27 FDA approved Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) (BLA 761381) Sponsor: BRISTOL-MYERS SQUIBB. Class: Type 3 - New Dosage Form.FDA approval (supplemental) — 2025-04-10 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Efficacy (BLA 761304 S-8) Sponsor: ARGENX BV. Class: Efficacy.FDA approval (supplemental) — 2025-05-23 FDA approved supplemental application for Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) — Labeling (BLA 761381 S-8) Sponsor: BRISTOL-MYERS SQUIBB. Class: Labeling.FDA approval (supplemental) — 2025-08-18 FDA approved supplemental application for Ocrevus Zunovo (ocrelizumab and hyaluronidase) — Labeling (BLA 761371 S-1) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2025-08-18 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Labeling (BLA 761347 S-2) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2025-08-18 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-57) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2025-10-02 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-58) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2025-10-02 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Efficacy (BLA 761347 S-3) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2025-10-17 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Efficacy (BLA 761304 S-10) Sponsor: ARGENX BV. Class: Efficacy.FDA approval (supplemental) — 2025-10-27 FDA approved supplemental application for Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) — Efficacy (BLA 761381 S-1) Sponsor: BRISTOL-MYERS SQUIBB. Class: Efficacy.FDA approval (supplemental) — 2025-10-27 FDA approved supplemental application for Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) — Efficacy (BLA 761381 S-2) Sponsor: BRISTOL-MYERS SQUIBB. Class: Efficacy.FDA approval (supplemental) — 2025-11-06 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-29) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2025-11-14 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-35) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval (supplemental) — 2025-11-17 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-59) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2025-11-17 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Labeling (BLA 761347 S-5) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2025-11-19 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-32) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2025-11-24 FDA approved supplemental application for Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) — Efficacy (BLA 761381 S-5) Sponsor: BRISTOL-MYERS SQUIBB. Class: Efficacy.FDA approval (supplemental) — 2025-11-24 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Efficacy (BLA 761347 S-4) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval — 2025-12-17 FDA approved Rybrevant Faspro (amivantamab and hyaluronidase-lpuj (human recombinant)) (BLA 761433) Sponsor: JANSSEN BIOTECH. Class: Type 5 - New Formulation or New Manufacturer.FDA approval (supplemental) — 2026-01-27 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Efficacy (BLA 761145 S-28) Sponsor: JANSSEN BIOTECH. Class: Efficacy.FDA approval (supplemental) — 2026-02-12 FDA approved supplemental application for Darzalex Faspro (daratumumab and hyaluronidase-fihj (human recombinant)) — Labeling (BLA 761145 S-39) Sponsor: JANSSEN BIOTECH. Class: Labeling.FDA approval — 2026-02-13 FDA approved Rybrevant Faspro (amivantamab and hyaluronidase-lpuj (human recombinant)) (BLA 761484) Sponsor: JANSSEN BIOTECH. Class: Type 5 - New Formulation or New Manufacturer.FDA approval (supplemental) — 2026-02-26 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Labeling (BLA 761304 S-19) Sponsor: ARGENX BV. Class: Labeling.FDA approval (supplemental) — 2026-05-08 FDA approved supplemental application for Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase (human recombinant)) — Efficacy (BLA 761304 S-18) Sponsor: ARGENX BV. Class: Efficacy.FDA approval (supplemental) — 2026-05-12 FDA approved supplemental application for Opdivo Qvantig (nivolumab and hyaluronidase-nvhy) — Labeling (BLA 761381 S-12) Sponsor: BRISTOL-MYERS SQUIBB. Class: Labeling.FDA approval (supplemental) — 2026-05-12 FDA approved supplemental application for Tecentriq (atezolizumab) — Labeling (BLA 761034 S-62) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2026-05-12 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Labeling (BLA 761347 S-9) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2026-05-15 FDA approved supplemental application for Tecentriq (atezolizumab) — Efficacy (BLA 761034 S-61) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2026-05-15 FDA approved supplemental application for Tecentriq Hybreza (atezolizumab and hyaluronidase-tqjs) — Efficacy (BLA 761347 S-8) Sponsor: GENENTECH INC. Class: Efficacy.FDA approval (supplemental) — 2026-05-18 FDA approved supplemental application for Herceptin Hylecta (trastuzumab and hyaluronidase-oysk) — Labeling (BLA 761106 S-14) Sponsor: GENENTECH INC. Class: Labeling.FDA approval (supplemental) — 2026-05-18 FDA approved supplemental application for Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) — Labeling (BLA 761170 S-16) Sponsor: GENENTECH INC. Class: Labeling.Label revision — 2026-05-21 Boxed warning present on label on Phesgo label (effective 2026-05-21) WARNING: CARDIOMYOPATHY, EMBRYO-FETAL TOXICITY, and PULMONARY TOXICITY WARNING: CARDIOMYOPATHY, EMBRYO-FETAL TOXICITY, and PULMONARY TOXICITY See full prescribing information for complete boxed warning. Cardiomyopathy: PHESGO administrationLabel revision — 2026-05-29 Boxed warning present on label on Herceptin Hylecta label (effective 2026-05-29) WARNING: CARDIOMYOPATHY, EMBRYO-FETAL TOXICITY, and PULMONARY TOXICITY WARNING: CARDIOMYOPATHY, EMBRYO-FETAL TOXICITY, and PULMONARY TOXICITY See full prescribing information for complete boxed warning. Cardiomyopathy: HERCEPTIN HYLECTA canRecall — 2024-09-11 HYLENEX RECOMBINANT recall — Class II: cGMP Deviations: Temperature excursion Hylenex recombinant (hyaluronidase) injection, 150 USP units/mL, 4x1 mL Single Dose Vials, Rx only, Manufactured for and marketed by Halozyme, Inc., 12390 El Camino Real San Diego California 92130, Distributed by Antares Pharma, Inc., EwingResults posted — 2011-11-23 Trial results posted: NCT00477152 Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and ChildrenResults posted — 2016-12-16 Trial results posted: NCT01846416 A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung CResults posted — 2017-01-04 Trial results posted: NCT02108652 A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 2)Results posted — 2017-03-23 Trial results posted: NCT02031458 A Study of Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell LungResults posted — 2017-04-21 Trial results posted: NCT02951767 A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1)Results posted — 2017-05-23 Trial results posted: NCT01903993 A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced Results posted — 2017-07-02 Trial results posted: NCT02008227 A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have FailResults posted — 2017-12-21 Trial results posted: NCT01984242 A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) as Monotherapy or in Combination With Bevacizumab (AResults posted — 2018-04-11 Trial results posted: NCT02302807 A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211Results posted — 2018-10-03 Trial results posted: NCT02420821 A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)Results posted — 2018-11-14 Trial results posted: NCT02409355 A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous NResults posted — 2019-02-12 Trial results posted: NCT02924883 A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in ParticipantResults posted — 2019-04-03 Trial results posted: NCT02367781 A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants WitResults posted — 2019-05-31 Trial results posted: NCT03029832 A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or MetastaticResults posted — 2019-06-13 Trial results posted: NCT02596971 A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, ViResults posted — 2019-06-13 Trial results posted: NCT02763579 A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung CanceResults posted — 2019-06-18 Trial results posted: NCT02788279 A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants Results posted — 2019-07-23 Trial results posted: NCT03023423 A Study of Daratumumab in Combination With Atezolizumab Compared With Atezolizumab Alone in Participants With Previously Treated Advanced orResults posted — 2019-11-05 Trial results posted: NCT02729896 A Study Evaluating Safety and Efficacy of Obinutuzumab, Polatuzumab Vedotin (Pola), and Atezolizumab (Atezo) in Participants With Relapsed oResults posted — 2019-11-12 Trial results posted: NCT02367794 A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-PaclitaResults posted — 2019-11-13 Trial results posted: NCT02322814 A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel Results posted — 2019-11-14 Trial results posted: NCT03120676 Study of Atezolizumab in Relapsed or Refractory Hodgkin LymphomaResults posted — 2019-12-30 Trial results posted: NCT02631577 A Study Evaluating the Safety and Efficacy of Atezolizumab in Combination With Obinutuzumab Plus Lenalidomide in Patients With Relapsed or RResults posted — 2020-02-05 Trial results posted: NCT02873195 Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal CancerResults posted — 2020-02-07 Trial results posted: NCT03267940 Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in PartiResults posted — 2020-02-25 Trial results posted: NCT02541604 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed DeResults posted — 2020-04-28 Trial results posted: NCT02848651 A Study of Atezolizumab as First-line Monotherapy for Advanced or Metastatic Non-Small Cell Lung CancerResults posted — 2020-05-14 Trial results posted: NCT02609984 Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002Results posted — 2020-05-15 Trial results posted: NCT03455556 Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung CancerResults posted — 2020-06-09 Trial results posted: NCT03273153 A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type MelanomaResults posted — 2020-06-12 Trial results posted: NCT03178851 Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or Results posted — 2020-06-26 Trial results posted: NCT02926833 Study of Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Adults With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)Results posted — 2020-07-09 Trial results posted: NCT03563716 A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell LuResults posted — 2020-07-24 Trial results posted: NCT02291289 A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)Results posted — 2020-10-09 Trial results posted: NCT02657434 A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in ParResults posted — 2020-10-27 Trial results posted: NCT02366143 A Study of Atezolizumab in Combination With Carboplatin Plus (+) Paclitaxel With or Without Bevacizumab Compared With Carboplatin+PaclitaxelResults posted — 2020-11-18 Trial results posted: NCT02450331 A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) AfteResults posted — 2020-11-19 Trial results posted: NCT02908672 A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 MuResults posted — 2020-12-23 Trial results posted: NCT03979066 Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal AdenocarcinomaResults posted — 2021-01-07 Trial results posted: NCT03125902 A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or MetastatiResults posted — 2021-01-12 Trial results posted: NCT03465891 Study of the PD-L1 Inhibitor Atezolizumab With or Without Low-dose, Local Radiation in Patients With Relapsed or Refractory Advanced Stage FResults posted — 2021-02-18 Trial results posted: NCT02409342 A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants Results posted — 2021-03-01 Trial results posted: NCT03264066 A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid TumorsResults posted — 2021-04-21 Trial results posted: NCT02724878 Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell CarcinomaResults posted — 2021-04-30 Trial results posted: NCT03016312 A Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide in Participants With Metastatic Castration-Resistant ProstratResults posted — 2021-05-17 Trial results posted: NCT02425891 A Study of Atezolizumab in Combination With Nab-Paclitaxel Compared With Placebo With Nab-Paclitaxel for Participants With Previously UntreaResults posted — 2021-05-17 Trial results posted: NCT02927301 A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation ConsortiResults posted — 2021-06-02 Trial results posted: NCT03197935 A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Results posted — 2021-06-04 Trial results posted: NCT02458638 A Study of Atezolizumab in Advanced Solid TumorsResults posted — 2021-06-09 Trial results posted: NCT03256344 Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver MetastasesResults posted — 2021-08-10 Trial results posted: NCT03394885 Atezolizumab With Neoadjuvant Chemotherapy for Patients With Newly-Diagnosed Advanced-Stage Ovarian CancerResults posted — 2021-08-11 Trial results posted: NCT03566485 Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast CancerResults posted — 2021-09-22 Trial results posted: NCT03115801 A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary CancersResults posted — 2021-10-28 Trial results posted: NCT02792192 Safety and Pharmacology Study of Atezolizumab Alone and in Combination With Bacille Calmette-Guérin (BCG) in High-Risk Non-Muscle-Invasive BResults posted — 2021-11-05 Trial results posted: NCT03434379 A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic HeResults posted — 2021-11-08 Trial results posted: NCT04422210 A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, AndResults posted — 2022-02-21 Trial results posted: NCT03922477 A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/oResults posted — 2022-03-25 Trial results posted: NCT03726879 A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide FollowResults posted — 2022-04-27 Trial results posted: NCT03628716 CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder CancerResults posted — 2022-05-06 Trial results posted: NCT03041311 Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLCResults posted — 2022-06-22 Trial results posted: NCT03050060 Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With AdResults posted — 2022-06-24 Trial results posted: NCT03730012 A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLTResults posted — 2022-08-11 Trial results posted: NCT03689855 Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLCResults posted — 2023-02-17 Trial results posted: NCT03038100 A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed StaResults posted — 2023-02-21 Trial results posted: NCT03386721 Basket Study to Evaluate the Therapeutic Activity of Simlukafusp Alfa as a Combination Therapy in Participants With Advanced and/or MetastatResults posted — 2023-02-21 Trial results posted: NCT02921269 Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical CancerResults posted — 2023-02-28 Trial results posted: NCT03312530 A Study of Cobimetinib Administered as Single Agent and in Combination With Venetoclax, With or Without Atezolizumab, in Participants With RResults posted — 2023-03-01 Trial results posted: NCT03713944 Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous NResults posted — 2023-03-09 Trial results posted: NCT03138889 Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid TumorsResults posted — 2023-03-21 Trial results posted: NCT03853707 Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic TriplResults posted — 2023-04-05 Trial results posted: NCT03073525 A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological CancersResults posted — 2023-04-13 Trial results posted: NCT04426825 A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell LuResults posted — 2023-05-17 Trial results posted: NCT03191786 A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or MetaResults posted — 2023-05-24 Trial results posted: NCT03102242 Atezolizumab Immunotherapy in Patients With Advanced NSCLCResults posted — 2023-06-02 Trial results posted: NCT04081688 Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLCResults posted — 2023-06-02 Trial results posted: NCT04373369 Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung CancerResults posted — 2023-06-08 Trial results posted: NCT03637764 Safety, Preliminary Efficacy and PK of Isatuximab (SAR650984) Alone or in Combination With Atezolizumab in Patients With Advanced MalignanciResults posted — 2023-06-13 Trial results posted: NCT03735121 A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung CancResults posted — 2023-06-27 Trial results posted: NCT04631029 Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin anResults posted — 2023-06-29 Trial results posted: NCT04677504 A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced BiliResults posted — 2023-07-11 Trial results posted: NCT03201458 Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or GallbladResults posted — 2023-07-20 Trial results posted: NCT03738228 Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA CerResults posted — 2023-07-21 Trial results posted: NCT02919449 Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With AtezolizumabResults posted — 2023-08-03 Trial results posted: NCT04639245 Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of MetastatResults posted — 2023-08-03 Trial results posted: NCT03024996 A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Results posted — 2023-09-05 Trial results posted: NCT05110781 Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic PrimarResults posted — 2023-09-13 Trial results posted: NCT03206203 Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast CancerResults posted — 2023-09-13 Trial results posted: NCT03737123 Trial of Atezolizumab Plus Chemotherapy After Progression on PD-1 or PD-L1 in Cisplatin-ineligible Patients With Advanced Urothelial CarcinoResults posted — 2023-09-14 Trial results posted: NCT02708680 Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead InResults posted — 2023-10-13 Trial results posted: NCT04045613 Derazantinib and Atezolizumab in Patients With Urothelial CancerResults posted — 2023-10-23 Trial results posted: NCT04458922 Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced ChondrosarcomaResults posted — 2023-11-07 Trial results posted: NCT03555149 A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal CanResults posted — 2023-11-18 Trial results posted: NCT04102098 A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High RiResults posted — 2023-12-04 Trial results posted: NCT04690855 A Study to Evaluate TAlazoparib, Radiotherapy and Atezolizumab in gBRCA 1/2 Negative Patients With PD-L1+ Metastatic Triple Negative Breast Results posted — 2023-12-13 Trial results posted: NCT03014648 Evaluating the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer (NSCLC)Results posted — 2023-12-13 Trial results posted: NCT02807636 Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Results posted — 2023-12-15 Trial results posted: NCT02844816 Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder CancerResults posted — 2023-12-20 Trial results posted: NCT04471428 Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously TrResults posted — 2023-12-22 Trial results posted: NCT03483012 Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain MetastasisResults posted — 2023-12-26 Trial results posted: NCT04099836 Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving OsimertinibResults posted — 2024-02-08 Trial results posted: NCT03625141 A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System MetasResults posted — 2024-02-15 Trial results posted: NCT05060003 Tiragolumab Plus Atezolizumab Versus Atezolizumab in the Treatment of Stage II Melanoma Patients Who Are ctDNA-positive Following ResectionResults posted — 2024-02-28 Trial results posted: NCT04338269 A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma AResults posted — 2024-03-05 Trial results posted: NCT03228537 Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural MaResults posted — 2024-03-12 Trial results posted: NCT04793399 Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult PatientsResults posted — 2024-03-13 Trial results posted: NCT04610684 Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain MetastasesResults posted — 2024-03-27 Trial results posted: NCT04177108 A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic TResults posted — 2024-04-04 Trial results posted: NCT02928406 A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary TractResults posted — 2024-05-03 Trial results posted: NCT04167137 Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult ParticipantsResults posted — 2024-05-07 Trial results posted: NCT03417544 Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BCResults posted — 2024-05-31 Trial results posted: NCT02451423 Neoadjuvant Atezolizumab in Localized Bladder CancerResults posted — 2024-06-05 Trial results posted: NCT04541173 Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)Results posted — 2024-06-14 Trial results posted: NCT03498521 A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based ChemotherapyResults posted — 2024-06-18 Trial results posted: NCT02883062 Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-NegatiResults posted — 2024-07-03 Trial results posted: NCT03513952 Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial CarcinomaResults posted — 2024-07-23 Trial results posted: NCT02091141 My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against CResults posted — 2024-08-21 Trial results posted: NCT03498716 A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus ChemotherapResults posted — 2024-08-22 Trial results posted: NCT02594384 A Phase I Dose Escalation Study of the Safety and Pharmacokinetics of LAM-002A In Patients With Non-Hodgkin's LymphomaResults posted — 2024-09-05 Trial results posted: NCT03154827 Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)Results posted — 2024-09-19 Trial results posted: NCT04123470 A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant MelanomaResults posted — 2024-09-26 Trial results posted: NCT05191797 Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung CancerResults posted — 2024-10-04 Trial results posted: NCT05315713 An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab WithResults posted — 2024-10-09 Trial results posted: NCT03452137 A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally AdvancedResults posted — 2024-10-09 Trial results posted: NCT03526900 Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain MetastasisResults posted — 2024-10-17 Trial results posted: NCT04661150 A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced ResResults posted — 2024-10-24 Trial results posted: NCT04091217 Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal MelanomaResults posted — 2024-10-30 Trial results posted: NCT03800836 A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in ParticipantsResults posted — 2024-11-21 Trial results posted: NCT05171777 A Study to Evaluate Participant and Healthcare Professional Reported Preference for Subcutaneous Atezolizumab Compared With Intravenous AtezResults posted — 2024-12-10 Trial results posted: NCT05717400 Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-AResults posted — 2024-12-18 Trial results posted: NCT04214418 Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, HydResults posted — 2024-12-30 Trial results posted: NCT04923776 Liver Directed RT + Chemo-immunotherapy for ES-SCLCResults posted — 2025-01-07 Trial results posted: NCT03272217 Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial CancerResults posted — 2025-01-08 Trial results posted: NCT04632992 A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression PatternsResults posted — 2025-01-15 Trial results posted: NCT05776875 Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCCResults posted — 2025-01-23 Trial results posted: NCT03285763 A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced orResults posted — 2025-02-03 Trial results posted: NCT04710498 Neoadjuvant Atezolizumab in Surgically Resectable Advanced Cutaneous Squamous Cell CarcinomaResults posted — 2025-02-07 Trial results posted: NCT04300647 A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive CervicResults posted — 2025-02-25 Trial results posted: NCT04322643 Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial CarcinomaResults posted — 2025-03-04 Trial results posted: NCT02839707 Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian TuResults posted — 2025-03-18 Trial results posted: NCT04101357 Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411Results posted — 2025-03-20 Trial results posted: NCT03024437 Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell CarcinomaResults posted — 2025-03-30 Trial results posted: NCT05834348 A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.Results posted — 2025-03-30 Trial results posted: NCT02486718 Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With LunResults posted — 2025-04-02 Trial results posted: NCT03829501 A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-Results posted — 2025-04-02 Trial results posted: NCT04512430 Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated PatientsResults posted — 2025-04-09 Trial results posted: NCT03473756 Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial CarcinomaResults posted — 2025-04-24 Trial results posted: NCT04602078 Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial CarcinomaResults posted — 2025-05-08 Trial results posted: NCT04732286 A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments HepaResults posted — 2025-05-21 Trial results posted: NCT04642365 A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.Results posted — 2025-05-23 Trial results posted: NCT04941287 Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third AnResults posted — 2025-05-28 Trial results posted: NCT03108131 Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare TumorsResults posted — 2025-05-30 Trial results posted: NCT03694262 The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)Results posted — 2025-05-30 Trial results posted: NCT05224141 Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small CellResults posted — 2025-06-12 Trial results posted: NCT03811002 Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Results posted — 2025-07-15 Trial results posted: NCT04477759 Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck CancerResults posted — 2025-07-18 Trial results posted: NCT05116202 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)Results posted — 2025-08-08 Trial results posted: NCT04740918 A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth FacResults posted — 2025-08-20 Trial results posted: NCT05109442 Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing CancersResults posted — 2025-08-27 Trial results posted: NCT03977467 Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 InhibitorResults posted — 2025-09-15 Trial results posted: NCT05459129 A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the HResults posted — 2025-09-22 Trial results posted: NCT04487067 A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable HepatocResults posted — 2025-10-02 Trial results posted: NCT04751929 Abemaciclib With or Without Atezolizumab for mCRPCResults posted — 2025-10-22 Trial results posted: NCT05694013 Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical PracticeResults posted — 2025-10-22 Trial results posted: NCT03901573 High-Risk Skin Cancers With Atezolizumab Plus NT-I7Results posted — 2025-10-22 Trial results posted: NCT04256421 A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell LunResults posted — 2025-10-29 Trial results posted: NCT04665856 Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell LResults posted — 2025-11-10 Trial results posted: NCT03280563 A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HResults posted — 2025-11-12 Trial results posted: NCT03371017 A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast CancResults posted — 2025-11-21 Trial results posted: NCT03193190 A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-PaResults posted — 2025-12-04 Trial results posted: NCT03836066 Atezolizumab Plus Bevacizumab in First Line NSCLC PatientsResults posted — 2025-12-11 Trial results posted: NCT03755791 Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who HavResults posted — 2025-12-12 Trial results posted: NCT04862949 Organ-specific Responses to Atezolizumab Plus Bevacizumab in Advanced HCCResults posted — 2025-12-18 Trial results posted: NCT04446117 Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPCResults posted — 2025-12-26 Trial results posted: NCT04148911 A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative BResults posted — 2025-12-29 Trial results posted: NCT05091567 A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Results posted — 2025-12-30 Trial results posted: NCT03199885 Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast CancerResults posted — 2026-01-12 Trial results posted: NCT04770272 Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX TherapyResults posted — 2026-01-22 Trial results posted: NCT05746481 Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain MetastasesResults posted — 2026-02-17 Trial results posted: NCT02530489 Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast CancerResults posted — 2026-03-11 Trial results posted: NCT04832854 A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based ChemothResults posted — 2026-03-18 Trial results posted: NCT04902040 Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Results posted — 2026-03-20 Trial results posted: NCT04637594 Trying to Find the Correct Length of Treatment With Immune Checkpoint TherapyResults posted — 2026-04-09 Trial results posted: NCT04540211 A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line TResults posted — 2026-04-14 Trial results posted: NCT02912559 Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch RepairResults posted — 2026-04-15 Trial results posted: NCT05251948 An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal JunctioResults posted — 2026-04-24 Trial results posted: NCT04262154 Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Results posted — 2026-05-04 Trial results posted: NCT03554083 Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III MelanomaResults posted — 2026-05-05 Trial results posted: NCT04665843 A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-Results posted — 2026-05-12 Trial results posted: NCT04042558 A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung CancerResults posted — 2026-05-12 Trial results posted: NCT03337698 A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-SmaResults posted — 2026-05-12 Trial results posted: NCT04245085 ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung CarcinomaResults posted — 2026-05-14 Trial results posted: NCT03762018 BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural MesotheliomaResults posted — 2026-06-03 Trial results posted: NCT04513925 A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small CelResults posted — 2026-06-03 Trial results posted: NCT04619797 A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and CResults posted — 2026-06-10 Trial results posted: NCT06267001 A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell LunResults posted — 2026-06-11 Trial results posted: NCT04984811 NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLCPivotal publication — 2023-01-01 Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, ope (Lancet) IMbrave050 — A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or AblationPivotal publication — 2023-01-01 Atezolizumab plus cabozantinib versus cabozantinib monotherapy for patients with renal cell carcinoma after progression with previous immune checkpoint inhibito (Lancet) CONTACT-03 — A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor TreatmentPivotal publication — 2023-01-01 First-line atezolizumab monotherapy versus single-agent chemotherapy in patients with non-small-cell lung cancer ineligible for treatment with a platinum-contai (Lancet) IPSOS — A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable Pivotal publication — 2024-01-01 Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial. (Lancet) BEATcc — Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the CervixPivotal publication — 2025-01-01 Zanzalintinib plus atezolizumab versus regorafenib in refractory colorectal cancer (STELLAR-303): a randomised, open-label, phase 3 trial. (Lancet) STELLAR-303 — Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal CancerPivotal publication — 2025-01-01 Adjuvant Atezolizumab for Early Triple-Negative Breast Cancer: The ALEXANDRA/IMpassion030 Randomized Clinical Trial. (JAMA) IMpassion030 — A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast CanPivotal publication — 2025-01-01 Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (IMforte): a randomised, mu (Lancet) IMforte — A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung CancerPivotal publication — 2025-01-01 Atezolizumab in High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Randomized Clinical Trial. (JAMA) IMvoke010 — A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and NeckPivotal publication — 2025-01-01 ctDNA-Guided Adjuvant Atezolizumab in Muscle-Invasive Bladder Cancer. (N Engl J Med) IMvigor011 — A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following CystectomyPivotal publication — 2026-01-01 Atezolizumab plus FOLFOX for Stage III Mismatch Repair-Deficient Colon Cancer. (N Engl J Med) Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repairtoday (2026-06-12)FDA approvalLabel revisionRecall or safetyTrial activityPivotal publication

Source: openFDA, ClinicalTrials.gov via AACT, PubMed · Hipa.ai, 2026-06-12Download chart as PNG

This page tracks every FDA action, clinical trial milestone, and major publication for Atezolizumab since 2005, drawn from openFDA, ClinicalTrials.gov, and PubMed.

All published updates (114)

2026
2025
2017

Upcoming & expected milestones

Primary completion· ClinicalTrials.gov
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Tre
Primary completion· ClinicalTrials.gov
An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locall
Primary completion· ClinicalTrials.gov
A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of
Primary completion· ClinicalTrials.gov
Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases
Primary completion· ClinicalTrials.gov
A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanc
Primary completion· ClinicalTrials.gov
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated Wit
Primary completion· ClinicalTrials.gov
Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus
Primary completion· ClinicalTrials.gov
A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin Americ
Trial started· ClinicalTrials.gov
Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant
Primary completion· ClinicalTrials.gov
Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs
Trial started· ClinicalTrials.gov
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Primary completion· ClinicalTrials.gov
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
Primary completion· ClinicalTrials.gov
Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer
Primary completion· ClinicalTrials.gov
Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER
Trial started· ClinicalTrials.gov
SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer
Primary completion· ClinicalTrials.gov
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Smal
Primary completion· ClinicalTrials.gov
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Adva
Primary completion· ClinicalTrials.gov
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
Primary completion· ClinicalTrials.gov
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Primary completion· ClinicalTrials.gov
A Clinical Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab or Atezolizumab Combined With Bevacizumab for the T
Primary completion· ClinicalTrials.gov
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Primary completion· ClinicalTrials.gov
A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extens
Primary completion· ClinicalTrials.gov
An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-
Primary completion· ClinicalTrials.gov
Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma

Past events

2026
Results posted· ClinicalTrials.gov
NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC
Results posted· ClinicalTrials.gov
A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lun
Trial started· ClinicalTrials.gov
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AAS
Results posted· ClinicalTrials.gov
A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cel
Results posted· ClinicalTrials.gov
A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and C
Trial started· ClinicalTrials.gov
SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer
Trial started· ClinicalTrials.gov
Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer
Results posted· ClinicalTrials.gov
A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer
Results posted· ClinicalTrials.gov
A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Sma
Results posted· ClinicalTrials.gov
ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma
Results posted· ClinicalTrials.gov
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-
Results posted· ClinicalTrials.gov
Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma
Trial started· ClinicalTrials.gov
Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma
Primary completion· ClinicalTrials.gov
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
Primary completion· ClinicalTrials.gov
Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.
Results posted· ClinicalTrials.gov
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive
Results posted· ClinicalTrials.gov
An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junctio
Results posted· ClinicalTrials.gov
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Trial started· ClinicalTrials.gov
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide
Results posted· ClinicalTrials.gov
A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line T
Trial started· ClinicalTrials.gov
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Primary completion· ClinicalTrials.gov
Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion
Trial started· ClinicalTrials.gov
Effects of Neoadjuvant Immunotherapy on Anti-tumour Immunity in Hepatocellular Carcinoma Patients Undergoing Liver Resection
Primary completion· ClinicalTrials.gov
Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC
Results posted· ClinicalTrials.gov
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted
Trial started· ClinicalTrials.gov
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advance
Primary completion· ClinicalTrials.gov
Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC
Results posted· ClinicalTrials.gov
A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemoth
Trial started· ClinicalTrials.gov
A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)
Primary completion· ClinicalTrials.gov
Efficacy and Safety of Yttrium-90 Microspheres Selective Internal Radiotherapy Combined with Immune Checkpoint Inhibitors and Anti-angiogene
Primary completion· ClinicalTrials.gov
To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC
Trial started· ClinicalTrials.gov
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Results posted· ClinicalTrials.gov
Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer
Primary completion· ClinicalTrials.gov
A Phase II Study of Atezolizumab in Combination With Bevacizumab, Carboplatin or Cisplatin, and Pemetrexed for EGFR-mutant Metastatic Non-sm
Trial started· ClinicalTrials.gov
A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)
Results posted· ClinicalTrials.gov
Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
Trial started· ClinicalTrials.gov
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Trial started· ClinicalTrials.gov
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2
Results posted· ClinicalTrials.gov
Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy
Trial started· ClinicalTrials.gov
Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hepatocellular Carcinom
Trial started· ClinicalTrials.gov
Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizuma
2025
Primary completion· ClinicalTrials.gov
Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements
Trial started· ClinicalTrials.gov
A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic
Primary completion· ClinicalTrials.gov
Clinical Trial of Atezolizumab With Paclitaxel, Trastuzumab, and Pertuzumab in Patients With Metastatic HER-2 Positive Breast Cancer
Primary completion· ClinicalTrials.gov
Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer
Results posted· ClinicalTrials.gov
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
Primary completion· ClinicalTrials.gov
A Study of Tiragolumab in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously U
Primary completion· ClinicalTrials.gov
Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma
Primary completion· ClinicalTrials.gov
A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Can
Results posted· ClinicalTrials.gov
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With
Results posted· ClinicalTrials.gov
A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative B
Primary completion· ClinicalTrials.gov
A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Pa
Results posted· ClinicalTrials.gov
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
Primary completion· ClinicalTrials.gov
A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lun
Results posted· ClinicalTrials.gov
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Hav
Primary completion· ClinicalTrials.gov
An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Anothe
Trial started· ClinicalTrials.gov
Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated
Trial started· ClinicalTrials.gov
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With
Trial started· ClinicalTrials.gov
Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC
Trial started· ClinicalTrials.gov
Open-Label, Biomarker-Integrated Umbrella Trial for First-Line Treatment of Extensive-stage Small Cell Lung Cancer
Trial started· ClinicalTrials.gov
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab
Results posted· ClinicalTrials.gov
A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pa
Primary completion· ClinicalTrials.gov
EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Meta
Results posted· ClinicalTrials.gov
A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Canc
Trial started· ClinicalTrials.gov
Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellu
Results posted· ClinicalTrials.gov
A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (H
Primary completion· ClinicalTrials.gov
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patien
Trial started· ClinicalTrials.gov
Efficacy of the Combination of Trimipramine and Atezolizumab With Bevacizumab in Patients With Recurrent Glioblastoma: a Phase 2 Trial
Results posted· ClinicalTrials.gov
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell L
Results posted· ClinicalTrials.gov
Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice
Results posted· ClinicalTrials.gov
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lun
Primary completion· ClinicalTrials.gov
A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Sma
Primary completion· ClinicalTrials.gov
A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastr
Primary completion· ClinicalTrials.gov
Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (
Primary completion· ClinicalTrials.gov
Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 Trial
Primary completion· ClinicalTrials.gov
A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants
Primary completion· ClinicalTrials.gov
A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select
Primary completion· ClinicalTrials.gov
Evaluating the Efficacy and Safety of Bevacizumab, Carboplatin, Gemcitabine and Atezolizumab in Breast Cancer
Primary completion· ClinicalTrials.gov
Doxorubicin Alone Versus Atezolizumab Alone Versus Doxorubicin and Atezolizumab in Recurrent Cervical Cancer
Primary completion· ClinicalTrials.gov
A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doubl
Results posted· ClinicalTrials.gov
A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatoc
Primary completion· ClinicalTrials.gov
All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Primary completion· ClinicalTrials.gov
Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer
Trial started· ClinicalTrials.gov
Systemic Chemotherapy With FOLFOX Plus Atezolizumab & Bevacizumab for Patients With Advanced HCC Who Previously Received Atezolizumab & Beva
Results posted· ClinicalTrials.gov
A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the H
Primary completion· ClinicalTrials.gov
A Phase III Study of Bevacizumab and Paclitaxel in Combination With Atezolizumab as a Treatment for Locally Advanced Unresectable or Metasta
Trial started· ClinicalTrials.gov
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Ad
Primary completion· ClinicalTrials.gov
An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junctio
Primary completion· ClinicalTrials.gov
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix
Primary completion· ClinicalTrials.gov
Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)
Primary completion· ClinicalTrials.gov
A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular C
Results posted· ClinicalTrials.gov
Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor
Trial started· ClinicalTrials.gov
Efficacy and Safety Analysis of First-Line ABCP Therapy in Advanced SMARCA4-Mutated NSCLC

Sources

FDA approvals, label revisions, and recalls come from the public openFDA APIs (Drugs@FDA, Drug Label, Drug Enforcement). Drug-safety communications come from the FDA RSS feed. Trial milestones come from ClinicalTrials.gov via the AACT pg dump. Pivotal-publication events come from PubMed, filtered to high-impact journals linked to a Phase 3 trial in our inventory.