ALN-ANG3 Clinical Trials (2026): 2 Studies for Diabetic Kidney Disease (DKD) & Healthy Volunteers With Hyperlipidemia
Hipa.ai Research · Source: ClinicalTrials.gov / AACT
Synced daily from ClinicalTrials.gov via AACT. Last sync: .
2 ALN-ANG3 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 2 indications (including Diabetic Kidney Disease (DKD) & Healthy Volunteers With Hyperlipidemia) and 329 total planned enrollment. 1 ALN-ANG3 clinical trial is actively recruiting at 51 U.S. sites across 15 states. Most recent activity: NCT07271186 (Apr 2028).
Where to Participate: All ALN-ANG3 Trial Sites in the U.S. (51 sites across 15 states)
Every actively recruiting ALN-ANG3trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.
| State | Facility | City | Trial | Map |
|---|---|---|---|---|
| AL | Apogee Clinical Research, LLC | Huntsville35801 | NCT07271186 | Map |
| AR | Applied Research Center of Arkansas | Little Rock72205 | NCT07271186 | Map |
| CA | AME Clinical Research | Huntington Beach92647 | NCT07271186 | Map |
| CA | Amicis Research Center | Northridge91325 | NCT07271186 | Map |
| CA | FOMAT - Vista del Mar Medical Group | Oxnard93036 | NCT07271186 | Map |
| CA | Central Coast Nephrology | Salinas93901 | NCT07271186 | Map |
| CA | North America Research Institute | San Dimas91773 | NCT07271186 | Map |
| CA | Amicis Research Center | Santa Clarita91355 | NCT07271186 | Map |
| CA | Valiance Clinical Research | Tarzana91356 | NCT07271186 | Map |
| CA | Amicis Research Center | Valencia91355 | NCT07271186 | Map |
| CA | National Institute of Clinical Research, Inc. | Victorville92392 | NCT07271186 | Map |
| FL | D&H Doral Research Center | Doral33122 | NCT07271186 | Map |
| FL | AGA Clinical Trials | Hialeah33012 | NCT07271186 | Map |
| FL | Convenient Medical Center | Hialeah33013 | NCT07271186 | Map |
| FL | Elixia Hollywood | Hollywood33024 | NCT07271186 | Map |
| FL | D&H Pompano Research Center | Margate33063 | NCT07271186 | Map |
| FL | D&H National Research Centers, Inc | Miami33155 | NCT07271186 | Map |
| FL | LCC Medical Research Institute | Miami33126 | NCT07271186 | Map |
| FL | Regenerate Primary Medical Research, LLC | Miami33155 | NCT07271186 | Map |
| FL | Ocean Blue Medical Research Center - Internal Medicine | Miami Springs33166 | NCT07271186 | Map |
| FL | Innovia Research Center | Miramar33027 | NCT07271186 | Map |
| FL | Central Florida Kidney Specialists Oakwater | Orlando32806 | NCT07271186 | Map |
| FL | Bolanos Clinical Research | Pembroke Pines33026 | NCT07271186 | Map |
| FL | Progressive Medical Research | Port Orange32127 | NCT07271186 | Map |
| FL | CDC Research Institute | Port Saint Lucie34952 | NCT07271186 | Map |
| FL | D&H Tamarac Research Center | Tamarac33321 | NCT07271186 | Map |
| FL | Metabolic Research Institute | West Palm Beach33401 | NCT07271186 | Map |
| GA | Privia Medical Group of Georgia, LLC | Savannah31406 | NCT07271186 | Map |
| IL | Research by Design, LLC - Internal Medicine | Chicago60643 | NCT07271186 | Map |
| LA | IMA Clinical Research | Monroe71201 | NCT07271186 | Map |
| MI | Elixia Michigan Kidney Consultants | Pontiac48341 | NCT07271186 | Map |
| MO | Elixia MNA | City of Saint Peters63376 | NCT07271186 | Map |
| MO | Clinical Research Consultants, LLC | Kansas City64111 | NCT07271186 | Map |
| NV | DaVita Clinical Research | Las Vegas89107 | NCT07271186 | Map |
| NY | Velocity Clinical Research | Binghamton13905 | NCT07271186 | Map |
| NY | CHEAR Center LLC | The Bronx10455 | NCT07271186 | Map |
| NC | Eastern Nephrology Associates - Greenville West | Greenville27834 | NCT07271186 | Map |
| NC | Brookview Hills Research Associates, LLC | Winston-Salem27103 | NCT07271186 | Map |
| PA | Northeast Clinical Research Center | Bethlehem18017 | NCT07271186 | Map |
| PA | Suburban Research Associates | West Chester19380 | NCT07271186 | Map |
| TN | Southeast Renal Research Institute | Chattanooga37404 | NCT07271186 | Map |
| TX | Arlington Nephrology, PLLC. | Arlington76015 | NCT07271186 | Map |
| TX | M3 Wake Research Dallas - Internal Medicine | Dallas75224 | NCT07271186 | Map |
| TX | Revival Research Institute, LLC | Dallas75231 | NCT07271186 | Map |
| TX | El Paso Kidney Specialists-Davita Clinical Research | El Paso79902 | NCT07271186 | Map |
| TX | Clinical Trial Network, LLC | Houston77074 | NCT07271186 | Map |
| TX | Juno Research, LLC | Houston77040 | NCT07271186 | Map |
| TX | Gulf Coast Clinical Research | Katy77450 | NCT07271186 | Map |
| TX | R & H Clinical Research, Inc. | Katy77450 | NCT07271186 | Map |
| TX | Sunbeam Clinical Research | McKinney75069 | NCT07271186 | Map |
| TX | Clinical Advancement Center | San Antonio78212 | NCT07271186 | Map |
ALN-ANG3 clinical trials at a glance: phase × recruitment status
| Phase | recruiting | active not recruiting | Total |
|---|---|---|---|
| P1 | 1 | 1 | |
| P2 | 1 | 1 |
Recruiting ALN-ANG3 clinical trials (1)
Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).
| NCT ID | Title | Phase | Indication | Enrollment | Started |
|---|---|---|---|---|---|
| NCT07271186 | ANCHOR-POCStudy to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease | P2 | Diabetic Kidney Disease (DKD) | 270 | Jan 2026 |
ALN-ANG3 clinical trials by indication
Diabetic Kidney Disease (DKD) (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT07271186 | ANCHOR-POC | P2 | recruiting | Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease |
Healthy Volunteers With Hyperlipidemia (1)
| NCT | Acronym | Phase | Status | Title |
|---|---|---|---|---|
| NCT06452771 | FIH | P1 | active not recruiting | A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults |
ALN-ANG3 pivotal trial highlights (Phase 2/3/4)
Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.
| Acronym | NCT | Phase | Status | Indication | Enrollment | PubMed |
|---|---|---|---|---|---|---|
| ANCHOR-POC | NCT07271186 | P2 | recruiting | Diabetic Kidney Disease (DKD) | 270 | — |
All ALN-ANG3 trials (2)
Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.
| NCT ID | Acronym | Title | Phase | Status | Enrollment | Sponsor | Started |
|---|---|---|---|---|---|---|---|
| NCT07271186 | ANCHOR-POC | Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease | P2 | recruiting | 270 | Regeneron Pharmaceuticals | Jan 2026 |
| NCT06452771 | FIH | A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults | P1 | active not recruiting | 59 | Regeneron Pharmaceuticals | Jun 2024 |
ALN-ANG3 clinical trials: frequently asked questions
- How many ALN-ANG3 clinical trials are there?
- 2 ALN-ANG3 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants.
- Are ALN-ANG3 clinical trials recruiting in 2026?
- Yes — 1 ALN-ANG3 trial is actively recruiting in 2026, with 51 U.S. sites across 15 states. See the recruiting trials and the per-state site list further down this page.
- What conditions is ALN-ANG3 being studied for?
- ALN-ANG3 is being studied for Diabetic Kidney Disease (DKD), Healthy Volunteers With Hyperlipidemia. The trials are grouped by indication on this page.
- What phase is ALN-ANG3 in?
- ALN-ANG3 clinical trials span 1 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
- Who sponsors ALN-ANG3 clinical trials?
- The lead sponsor across the most ALN-ANG3 trials is Regeneron Pharmaceuticals. Each trial row links to the full study detail page including sponsor information.
Sources and methodology
Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming ALN-ANG3as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.
Last refreshed .
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