ALN-ANG3 Clinical Trials (2026): 2 Studies for Diabetic Kidney Disease (DKD) & Healthy Volunteers With Hyperlipidemia

Hipa.ai Research · Source: ClinicalTrials.gov / AACT

Synced daily from ClinicalTrials.gov via AACT. Last sync: .

2 ALN-ANG3 clinical trials are catalogued on Hipa.ai from the AACT mirror of ClinicalTrials.gov, spanning 2 indications (including Diabetic Kidney Disease (DKD) & Healthy Volunteers With Hyperlipidemia) and 329 total planned enrollment. 1 ALN-ANG3 clinical trial is actively recruiting at 51 U.S. sites across 15 states. Most recent activity: NCT07271186 (Apr 2028).

Where to Participate: All ALN-ANG3 Trial Sites in the U.S. (51 sites across 15 states)

Every actively recruiting ALN-ANG3trial site, sorted by state then city. Each row links to the trial detail page (eligibility, contacts, full study record). Sites no longer enrolling at the location level are excluded. ClinicalTrials.gov / AACT does not provide street-level addresses; the map link uses the facility's geocoded coordinates where available.

StateFacilityCityTrialMap
ALApogee Clinical Research, LLCHuntsville35801NCT07271186Map
ARApplied Research Center of ArkansasLittle Rock72205NCT07271186Map
CAAME Clinical ResearchHuntington Beach92647NCT07271186Map
CAAmicis Research CenterNorthridge91325NCT07271186Map
CAFOMAT - Vista del Mar Medical GroupOxnard93036NCT07271186Map
CACentral Coast NephrologySalinas93901NCT07271186Map
CANorth America Research InstituteSan Dimas91773NCT07271186Map
CAAmicis Research CenterSanta Clarita91355NCT07271186Map
CAValiance Clinical ResearchTarzana91356NCT07271186Map
CAAmicis Research CenterValencia91355NCT07271186Map
CANational Institute of Clinical Research, Inc.Victorville92392NCT07271186Map
FLD&H Doral Research CenterDoral33122NCT07271186Map
FLAGA Clinical TrialsHialeah33012NCT07271186Map
FLConvenient Medical CenterHialeah33013NCT07271186Map
FLElixia HollywoodHollywood33024NCT07271186Map
FLD&H Pompano Research CenterMargate33063NCT07271186Map
FLD&H National Research Centers, IncMiami33155NCT07271186Map
FLLCC Medical Research InstituteMiami33126NCT07271186Map
FLRegenerate Primary Medical Research, LLCMiami33155NCT07271186Map
FLOcean Blue Medical Research Center - Internal MedicineMiami Springs33166NCT07271186Map
FLInnovia Research CenterMiramar33027NCT07271186Map
FLCentral Florida Kidney Specialists OakwaterOrlando32806NCT07271186Map
FLBolanos Clinical ResearchPembroke Pines33026NCT07271186Map
FLProgressive Medical ResearchPort Orange32127NCT07271186Map
FLCDC Research InstitutePort Saint Lucie34952NCT07271186Map
FLD&H Tamarac Research CenterTamarac33321NCT07271186Map
FLMetabolic Research InstituteWest Palm Beach33401NCT07271186Map
GAPrivia Medical Group of Georgia, LLCSavannah31406NCT07271186Map
ILResearch by Design, LLC - Internal MedicineChicago60643NCT07271186Map
LAIMA Clinical ResearchMonroe71201NCT07271186Map
MIElixia Michigan Kidney ConsultantsPontiac48341NCT07271186Map
MOElixia MNACity of Saint Peters63376NCT07271186Map
MOClinical Research Consultants, LLCKansas City64111NCT07271186Map
NVDaVita Clinical ResearchLas Vegas89107NCT07271186Map
NYVelocity Clinical ResearchBinghamton13905NCT07271186Map
NYCHEAR Center LLCThe Bronx10455NCT07271186Map
NCEastern Nephrology Associates - Greenville WestGreenville27834NCT07271186Map
NCBrookview Hills Research Associates, LLCWinston-Salem27103NCT07271186Map
PANortheast Clinical Research CenterBethlehem18017NCT07271186Map
PASuburban Research AssociatesWest Chester19380NCT07271186Map
TNSoutheast Renal Research InstituteChattanooga37404NCT07271186Map
TXArlington Nephrology, PLLC.Arlington76015NCT07271186Map
TXM3 Wake Research Dallas - Internal MedicineDallas75224NCT07271186Map
TXRevival Research Institute, LLCDallas75231NCT07271186Map
TXEl Paso Kidney Specialists-Davita Clinical ResearchEl Paso79902NCT07271186Map
TXClinical Trial Network, LLCHouston77074NCT07271186Map
TXJuno Research, LLCHouston77040NCT07271186Map
TXGulf Coast Clinical ResearchKaty77450NCT07271186Map
TXR & H Clinical Research, Inc.Katy77450NCT07271186Map
TXSunbeam Clinical ResearchMcKinney75069NCT07271186Map
TXClinical Advancement CenterSan Antonio78212NCT07271186Map

ALN-ANG3 clinical trials at a glance: phase × recruitment status

Phaserecruitingactive not recruitingTotal
P111
P211

Recruiting ALN-ANG3 clinical trials (1)

Studies currently enrolling participants. Click any NCT ID to view the trial detail page (eligibility, sites, contacts).

NCT IDTitlePhaseIndicationEnrollmentStarted
NCT07271186ANCHOR-POCStudy to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney DiseaseP2Diabetic Kidney Disease (DKD)270Jan 2026

ALN-ANG3 clinical trials by indication

Diabetic Kidney Disease (DKD) (1)

NCTAcronymPhaseStatusTitle
NCT07271186ANCHOR-POCP2recruitingStudy to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Healthy Volunteers With Hyperlipidemia (1)

NCTAcronymPhaseStatusTitle
NCT06452771FIHP1active not recruitingA First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults

ALN-ANG3 pivotal trial highlights (Phase 2/3/4)

Phase-2/3/4 studies with named acronyms — the registration-grade trials most cited in label discussions and Wikipedia.

AcronymNCTPhaseStatusIndicationEnrollmentPubMed
ANCHOR-POCNCT07271186P2recruitingDiabetic Kidney Disease (DKD)270

All ALN-ANG3 trials (2)

Sorted by most recent activity (completion → start → posted date). Each row links to the trial detail page on Hipa.ai.

NCT IDAcronymTitlePhaseStatusEnrollmentSponsorStarted
NCT07271186ANCHOR-POCStudy to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney DiseaseP2recruiting270Regeneron PharmaceuticalsJan 2026
NCT06452771FIHA First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy AdultsP1active not recruiting59Regeneron PharmaceuticalsJun 2024

ALN-ANG3 clinical trials: frequently asked questions

How many ALN-ANG3 clinical trials are there?
2 ALN-ANG3 clinical trials are catalogued on Hipa.ai, sourced from the AACT mirror of ClinicalTrials.gov. 1 is actively recruiting participants.
Are ALN-ANG3 clinical trials recruiting in 2026?
Yes — 1 ALN-ANG3 trial is actively recruiting in 2026, with 51 U.S. sites across 15 states. See the recruiting trials and the per-state site list further down this page.
What conditions is ALN-ANG3 being studied for?
ALN-ANG3 is being studied for Diabetic Kidney Disease (DKD), Healthy Volunteers With Hyperlipidemia. The trials are grouped by indication on this page.
What phase is ALN-ANG3 in?
ALN-ANG3 clinical trials span 1 Phase 2, 1 Phase 1. The phase × status matrix at the top of this page breaks down counts by phase and recruitment status.
Who sponsors ALN-ANG3 clinical trials?
The lead sponsor across the most ALN-ANG3 trials is Regeneron Pharmaceuticals. Each trial row links to the full study detail page including sponsor information.

Sources and methodology

Trial inventory derived from the AACT mirror of ClinicalTrials.gov. Trials are filtered to those naming ALN-ANG3as an intervention. Phase, status, enrollment, sponsor, and dates are taken from the source `studies` table; primary indication is the first listed condition. Acronyms are extracted from each trial's brief title where present. PubMed links are populated for trials whose published primary outcomes have been indexed in our evidence cache.

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