Trial results for the Stroke and CPAP Outcome Study 3 (SCOUTS3) were posted on ClinicalTrials.gov on 2025-10-08, indicating that participants in the optimization arm used continuous positive airway pressure (CPAP) for a mean of 3.1 nightly hours.
Background
Obstructive sleep apnea (OSA), a condition characterized by breathing problems during sleep, is a significant risk factor for stroke and is highly prevalent among stroke survivors, affecting approximately two-thirds of this population. Evidence also suggests that OSA can lead to worse outcomes after a stroke. Continuous positive airway pressure (CPAP) therapy is a common treatment for OSA. The Stroke and CPAP Outcome Study 3 (SCOUTS3) was designed to investigate methods for improving the use of CPAP therapy when initiated during intensive stroke rehabilitation.
Trial design
This completed study, identified as Phase NA, enrolled 36 participants. The trial focused on individuals with conditions including Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, and Motivation. The study's objective was to explore how to improve adherence to CPAP therapy among stroke survivors. The intervention involved an optimization arm aimed at enhancing CPAP use, rather than testing a specific drug or device.
Key results
The primary measurement reported for the SCOUTS3 Optimization Arm was CPAP Adherence:
- The mean nightly hours of CPAP use was 3.1, with a standard deviation of 2.6.
What this means
The results from the SCOUTS3 Optimization Arm provide specific data on CPAP adherence levels among stroke survivors receiving an intervention aimed at improving use. The reported mean of 3.1 nightly hours of CPAP use, with a standard deviation of 2.6, offers a quantitative measure of adherence achieved within this study's context. These findings contribute to understanding the practical challenges and outcomes associated with CPAP utilization in a stroke rehabilitation setting, highlighting the observed level of engagement with the therapy.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT06029959, titled "Stroke and CPAP Outcome Study 3", were posted on 2025-10-08 on clinicaltrials.gov.