Trial results investigating the effects of device-assisted practice of activities of daily living (ADL) on arm and hand recovery in individuals with moderate to severe Stroke were posted on ClinicalTrials.gov on 2026-04-14. The study enrolled 53 participants to evaluate intervention-induced changes in clinical outcomes.
Background
Stroke is a leading cause of long-term disability, with a significant number of survivors experiencing impaired functional use of their paretic upper extremity. Restoring arm and hand function is a critical goal in stroke rehabilitation, as it directly impacts a patient's independence and quality of life. Current rehabilitation approaches aim to improve motor recovery, and the investigation of device-assisted practice of ADLs represents an effort to enhance these outcomes. Such interventions could potentially benefit a large population of stroke survivors by improving motor recovery and functional independence.
Trial design
This completed trial enrolled 53 participants diagnosed with Stroke. The study investigated the effects of device-assisted practice of activities of daily living (ADL) on upper extremity motor recovery. The trial phase was not applicable or specified. Primary outcomes were not listed in the posted results. The study collected data from two intervention groups: "ReIn-hand and Robot" and "ReIn-Hand".
Key results
The trial measured several clinical outcomes related to arm and hand recovery. Key results include:
- Box and Blocks Test (BBT):
- "ReIn-hand and Robot" group: Mean of 5.7 blocks (Standard Deviation: 9.4).
- "ReIn-Hand" group: Mean of 8.8 blocks (Standard Deviation: 9.2).
- Upper Extremity Fugl-Meyer Assessment Score:
- "ReIn-hand and Robot" group: Mean of 23.0 points (Standard Deviation: 8.6).
- "ReIn-Hand" group: Mean of 24.3 points (Standard Deviation: 8.6).
- Chedoke McMaster Stroke Assessment (CMSA) Hand Subscale:
- "ReIn-hand and Robot" group: Mean of 3.4 points (Standard Deviation: 0.8).
- "ReIn-Hand" group: Mean of 3.4 points (Standard Deviation: 0.8).
- Action Research Arm Test (ARAT):
- "ReIn-hand and Robot" group: Mean of 13.8 points (Standard Deviation: 11.7).
- "ReIn-Hand" group: Mean of 17.6 points (Standard Deviation: 13.1).
- Kinaesthesia Subscale of Nottingham Sensory Assessment:
- "ReIn-hand and Robot" group: Mean of 8.42 points (Standard Deviation: 2.26).
- "ReIn-Hand" group: Mean of 9.72 points (Standard Deviation: 5.98).
- Cutaneous Sensory Touch Threshold Using Semmes-Weinstein Monofilaments:
- "ReIn-hand and Robot" group: Mean of 4.51 points (Standard Deviation: 1.32).
- "ReIn-Hand" group: Mean of 4.59 points (Standard Deviation: 1.32).
What this means
The posted results provide specific measurements for various clinical outcomes related to upper extremity function and sensation in stroke survivors undergoing device-assisted rehabilitation. For instance, the "ReIn-Hand" group showed a mean of 8.8 blocks on the Box and Blocks Test, compared to 5.7 blocks for the "ReIn-hand and Robot" group. Similarly, the Action Research Arm Test showed a mean of 17.6 points for the "ReIn-Hand" group versus 13.8 points for the "ReIn-hand and Robot" group. These observed outcomes offer insights into the effects of different device-assisted practice approaches on arm and hand recovery. However, without comparative statistical analyses, definitive conclusions regarding the superiority or equivalence of these interventions cannot be drawn from these raw figures alone.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study titled "Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke" were posted on 2026-04-14 on clinicaltrials.gov.
